Improving Transition Outcomes: Resource Mapping Workshop: Interview Tips

Interview tips developed by Lois Smidt with Beyond Welfare in Ames, Iowa and shared at the Improving Transition Outcomes Resource Mapping Workshops

Improving Transition Outcomes: Resource Mapping Workshop: What is Resource Mapping?

Information shared at the Improving Transition Outcomes Resource Mapping Workshops

Improving Transition Outcomes: MyTransitionIowa.org Resource Mapping Product

Information about Improving Transition Outcomes statewide resource mapping product.

Improving Transition Outcomes: Youth Leadership Forum Alumni Survey

Results from a survey conducted in cooperation with Iowa's Youth Leadership Forum.

Improving Transition Outcomes: Community Demonstration Prototypes

Information on the Council Bluffs Youth Connections, Henry County Transition Partners, and CASE (Career And Self Awareness) community demonstration prototypes.

Improving Transition Outcomes: Introducing the Prototype Replication Templates

Brief overview of the three community demonstration prototypes established under Improving Transition Outcomes and an introduction to the Replication Templates developed to assist community teams.

Improving Transition Outcomes: Prototype First Year Highlights

Highlights from the community demonstration prototypes first year.

Improving Transition Outcomes: Prototype Work Plan Template

Work Plan template developed for the Improving Transition Outcomes community demonstration prototypes.

Improving Transition Outcomes: Capacity Building Forum: Dissemination of Promising Transition Practices

Information on the Promising Transition Practices shared at the September 28, 2007 Capacity Building Forum sponsored by Improving Transition Outcomes with Iowa Vocational Rehabilitation Services.

Improving Transition Outcomes: Sustainability Business Plan Template #1

Business Plan template developed for use by the Improving Transition Outcomes community demonstration prototypes in preparing for sustainability without grant funding.

Improving Transition Outcomes: Sustainability Business Plan Template #2

Business Plan template developed for use by the Improving Transition Outcomes community demonstration prototypes in preparing for sustainability without grant funding.

Improving Transition Outcomes: Sustainability Business Plan Template #3

Business Plan template developed for use by the Improving Transition Outcomes community demonstration prototypes in preparing for sustainability without grant funding.

Improving Transition Outcomes: State Transition Plan: Iowa's Youth Development Strategic Plan 2007-2010 developed by the Iowa Collaboration for Youth Development team

Iowa's youth development plan for fulfilling Iowa's Promise.

Improving Transition Outcomes: Henry County Transition Partners: Directory Part 1

Part 1 of 3 for Henry County's Transition Partners Resource Directory specific to youth with disabilities transitioning from high school to employment, post-secondary education, or adult services.

Improving the sensitivity of the sequence profile method.

The sequence profile method (Gribskov M, McLachlan AD, Eisenberg D, 1987, Proc Natl Acad Sci USA 84:4355-4358) is a powerful tool to detect distant relationships between amino acid sequences. A profile is a table of position-specific scores and gap penalties, providing a generalized description of a protein motif, which can be used for sequence alignments and database searches instead of an individual sequence. A sequence profile is derived from a multiple sequence alignment. We have found 2 ways to improve the sensitivity of sequence profiles: (1) Sequence weights: Usage of individual weights for each sequence avoids bias toward closely related sequences. These weights are automatically assigned based on the distance of the sequences using a published procedure (Sibbald PR, Argos P, 1990, J Mol Biol 216:813-818). (2) Amino acid substitution table: In addition to the alignment, the construction of a profile also needs an amino acid substitution table. We have found that in some cases a new table, the BLOSUM45 table (Henikoff S, Henikoff JG, 1992, Proc Natl Acad Sci USA 89:10915-10919), is more sensitive than the original Dayhoff table or the modified Dayhoff table used in the current implementation. Profiles derived by the improved method are more sensitive and selective in a number of cases where previous methods have failed to completely separate true members from false positives.