Number of prior episodes and the presence of depressive symptoms are associated with longer length of stay for patients with acute manic episodes

Background: Few studies have analyzed predictors of length of stay (LOS) in patients admitted due to acute bipolar manic episodes. The purpose of the present study was to estimate LOS and to determine the potential sociodemographic and clinical risk factors associated with a longer hospitalization. Such information could be useful to identify those patients at high risk for long LOS and to allocate them to special treatments, with the aim of optimizing their hospital management. Methods: This was a cross-sectional study recruiting adult patients with a diagnosis of bipolar disorder (Diagnostic and Statistical Manual of Mental Disorders, 4th edition, text revision (DSM-IV-TR) criteria) who had been hospitalized due to an acute manic episode with a Young Mania Rating Scale total score greater than 20. Bivariate correlational and multiple linear regression analyses were performed to identify independent predictors of LOS. Results: A total of 235 patients from 44 centers were included in the study. The only factors that were significantly associated to LOS in the regression model were the number of previous episodes and the Montgomery-Åsberg Depression Rating Scale (MADRS) total score at admission (P < 0.05). Conclusions: Patients with a high number of previous episodes and those with depressive symptoms during mania are more likely to stay longer in hospital. Patients with severe depressive symptoms may have a more severe or treatment-resistant course of the acute bipolar manic episode.

Emerging trends and experiences in Asia-Pacific aquaculture: 2003

This document provides an overview of topical issues in Asian aquaculture for 2003, including a review of its status, progress in research and development, major issues and experiences, together with suggestions on actions for addressing opportunities and constraints. The document has been prepared by NACA and FAO to facilitate discussions at the 15th NACA Governing Council meeting, hosted by the Government of Sri Lanka on 21st-25th April 2004. The final version will be widely circulated as the editors hope it will prove a useful document for all involved in aquaculture, and related fishery development in the Asia-Pacific region. Pending feedback on this 2003 document, further reviews may be considered by NACA and FAO as a way of bringing together regularly in one publication relevant and key issues facing development of aquaculture in the Asia-Pacific region. (PDF contains 153 pages)

Emerging Practice in a Digital Age: A guide to technology-enhanced institutional innovation

Since the launch of the JISC guide Innovative Practice with e-Learning (JISC, 2005), so much has changed. At that time, early adopters were exploring the potential of mobile and wireless learning. Since then, the increased availability of public and institutional wireless networks, the emergence of new and more powerful technologies and an increase in personal ownership of these technologies are changing the way we connect, communicate and collaborate. Emerging Practice in a Digital Age, one of a series of Effective Practice guides, draws on recent JISC reports and case studies and looks at how colleges and universities are continuing to embrace innovation and respond to changes in economic, social and technological circumstances in a fastchanging world.

Emerging technologies for reef fisheries research and management [held during the 56th annual Gulf and Caribbean Fisheries Institute meeting in Tortola, British Virgin Islands, November 2003]

This publication of the NOAA Professional Paper NMFS Series is the product of a special symposium on “Emerging Technologies for Reef Fisheries Research and Management” held during the 56th annual Gulf and Caribbean Fisheries Institute meeting in Tortola, British Virgin Islands, November 2003. The purpose of this collection is to highlight the diversity of questions and issues in reef fisheries management that are benefiting from applications of technology. Topics cover a wide variety of questions and issues from the study of individual behavior, distribution and abundance of groups and populations, and associations between habitats and fish and shellfish species.(PDF files contains 124 pages.)

USP1 deubiquitinase: cellular functions, regulatory mechanisms and emerging potential as target in cancer therapy

12 p.

Emerging technologies for reef fisheries research and management

This publication of the NOAA Professional Paper NMFS Series is the product of a special symposium on “Emerging Technologies for Reef Fisheries Research and Management” held during the 56th annual Gulf and Caribbean Fisheries Institute meeting in Tortola, British Virgin Islands, November 2003. The purpose of this collection is to highlight the diversity of questions and issues in reef fisheries management that are benefiting from applications of technology. Topics cover a wide variety of questions and issues from the study of individual behavior, distribution and abundance of groups and populations, and associations between habitats and fish and shellfish species.

O bifrontismo do feminino em A Demanda do Santo Graal: Redescobrindo o substrato céltico das personagens femininas na busca do Santo Cálix

A figura da mulher ocupa significativo papel nas novelas de cavalaria do Ciclo Bretão. Emergindo como um elemento que traz liga às narrativas do lendário artúrico, constitui-se adjuvante essencial e multifacetada na construção dos episódios, numa interação constante com o masculino representado, principalmente, pelos cavaleiros. O Medievo traz à tona uma imagem matizada do feminino: a mulher socialmente vista sob clivagens diversas é refletida na literatura de cavalaria, conforme se pode verificar em A Demanda do Santo Graal. A presença feminina é importantíssima na narrativa, sobretudo na sua tensa relação com a cavalaria, agora ligada ao elemento religioso - monastizada, celibatária e ascética. O objetivo precípuo de nossos estudos é investigar de que maneira a fôrma sociocultural medieva, na qual foi moldada A Demanda do Santo Graal, se relaciona com seu substrato: as narrativas provindas da cosmovisão inerente ao imaginário céltico. Desta feita, nosso viés analítico verticaliza-se no elemento feminino presente na obra. Mais especificamente, toma-se por escopo a imagem de personagens que refletem a ideologia clerical moralístico-didatizante do século XIII, mas, sobretudo, resgata-se a imagem de personagens imbuídas de singular dualidade; ambigüidade esta que é marca não só do medievo paradoxal concernente ao feminino, mas também de personas literárias concebidas entre dois mundos, dois pólos ideológicos distintos. Em outros termos, fala-se de personagens que são seres ficcionais bifrontes: personagens localizadas entre as herdades e as identidades. Foram tomados como corpora de pesquisa os episódios em que estas damas polidimensionais aparecem e se tornam adjuvantes na ação literária, seja para cooperar, confundir ou prejudicar os cavaleiros que empreendem a sagrada, inefável e venturosa busca do Santo Cálix que dará fim às aventuras do Reino de Logres

Emerging patterns of species richness, diversity, population density, and distribution in the skates (Rajidae) of Alaska

Six years of bottom-trawl survey data, including over 6000 trawls covering over 200 km2 of bottom area throughout Alaska’s subarctic marine waters, were analyzed for patterns in species richness, diversity, density, and distribution of skates. The Bering Sea continental shelf and slope, Aleutian Islands, and Gulf of Alaska regions were stratified by geographic subregion and depth. Species richness and relative density of skates increased with depth to the shelf break in all regions. The Bering Sea shelf was dominated by the Alaska skate (Bathyraja parmifera), but species richness and diversity were low. On the Bering Sea slope, richness and diversity were higher in the shallow stratum, and relative density appeared higher in subregions dominated by canyons. In the Aleutian Islands and Gulf of Alaska, species richness and relative density were generally highest in the deepest depth strata. The data and distribution maps presented here are based on species-level data collected throughout the marine waters of Alaska, and this article represents the most comprehensive summary of the skate fauna of the region published to date.

Cellular and molecular responses of zebrafish to legacy and emerging pollutants: the specific cases of PAHs and metal oxide nanoparticles

270 p.