Exploring the binding mechanism of Guaijaverin to human serum albumin: Fluorescence spectroscopy and computational approach

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Emergence of the Pointer Basis through the Dynamics of Correlations

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Environmentally induced antinociception and hyperalgesia in rats and mice

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Contribution of the rostral ventromedial medulla to post-anxiety induced hyperalgesia

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Aves colecionadas na localidade de Fazenda Caiuá (Paraná, Brasil) por Adolph Hempel, com discussão sobre a sua localizaç ão exata

The region known as the pioneer north of Paraná State can be considered one of the most severely modified in southern Brazil, due to the colonization that started at the end of 19th century. In this little known region, seldom visited by traveler naturalists of the past, the collector Adolph Hempel obtained an important series of bird specimens that constitute, in many cases, the only - and last - information concerning the avifauna of this region. For several reasons, Fazenda Cayoá has been associated with the State of São Paulo, although it was an important center for coffee in the early 20th. century and is near the left bank of Rio Paranapanema, thus in the State of Paraná.

Evaluación de un programa de innovación y sistemas de producción en América Latina: estudio sobre la dinámica de redes

Incluye Bibliografía

Influence of upper-body exercise order on hormonal responses in trained men

The aim of this study was to examine acute hormonal responses after different sequences of an upper-body resistance-exercise session. Twenty men completed 2 sessions (3 sets; 70% 1-repetition maximum; 2 min passive rest between sets) of the same exercises in opposite sequences (larger to smaller vs. smaller to larger muscle-group exercises). Total testosterone (TT), free testosterone (FT), testosterone/cortisol (T/C) ratio, sex-hormone-binding globulin (SHBG), growth hormone (GH), and cortisol (C) concentrations were measured before and immediately after each sequence. The results indicate that the GH concentration increased after both sessions, but the increase was significantly greater (p < 0.05) after the sequence in which larger muscle-group exercises were performed prior to the smaller muscle-group exercises. No differences were observed between sessions for TT, FT, SHBG, C, or the T/C ratio at baseline or immediately after resistance exercise. These results indicate that performing larger muscle-group exercises first in an upper-body resistance-exercise session leads to a significantly greater GH response. This may have been due to the significantly greater exercise volume accomplished. In summary, the findings of this investigation support the common prescriptive recommendation to perform larger-muscle group exercises first during a resistance-exercise session.

Why entanglement of formation is not generally monogamous

Unlike correlation of classical systems, entanglement of quantum systems cannot be distributed at will: if one system A is maximally entangled with another system B, it cannot be entangled at all with a third system C. This concept, known as the monogamy of entanglement, is manifest when the entanglement of A with a pair BC can be divided as contributions of the entanglement between A and B and A and C, plus a term τABC involving genuine tripartite entanglement and so expected to be always positive. A very important measure in quantum information theory, the entanglement of formation (EOF), fails to satisfy this last requirement. Here we present the reasons for that and show a set of conditions that an arbitrary pure tripartite state must satisfy for the EOF to become a monogamous measure, i.e., for τABC≥0. The relation derived is connected to the discrepancy between quantum and classical correlations, τABC being negative whenever the quantum correlation prevails over the classical one. This result is employed to elucidate features of the distribution of entanglement during a dynamical evolution. It also helps to relate all monogamous instances of the EOF to the squashed sntanglement, an entanglement measure that is always monogamous. © 2013 American Physical Society.

Molecularly designed layer-by-layer (LbL) films to detect catechol using information visualization methods

The control of molecular architectures has been exploited in layer-by-layer (LbL) films deposited on Au interdigitated electrodes, thus forming an electronic tongue (e-tongue) system that reached an unprecedented high sensitivity (down to 10-12 M) in detecting catechol. Such high sensitivity was made possible upon using units containing the enzyme tyrosinase, which interacted specifically with catechol, and by processing impedance spectroscopy data with information visualization methods. These latter methods, including the parallel coordinates technique, were also useful for identifying the major contributors to the high distinguishing ability toward catechol. Among several film architectures tested, the most efficient had a tyrosinase layer deposited atop LbL films of alternating layers of dioctadecyldimethylammonium bromide (DODAB) and 1,2-dipalmitoyl-sn-3-glycero-fosfo-rac-(1-glycerol) (DPPG), viz., (DODAB/DPPG)5/DODAB/Tyr. The latter represents a more suitable medium for immobilizing tyrosinase when compared to conventional polyelectrolytes. Furthermore, the distinction was more effective at low frequencies where double-layer effects on the film/liquid sample dominate the electrical response. Because the optimization of film architectures based on information visualization is completely generic, the approach presented here may be extended to designing architectures for other types of applications in addition to sensing and biosensing. © 2013 American Chemical Society.

Influence of the concentration of polyols on the rheological and spectral characteristics of guar gum

Polyols are widely used as sugar substitutes and provide texture to foods. Guar gum has many applications in food industry such as increasing product viscosity and improving texture. Knowledge of rheological properties of gum/polyol systems is important to permit replacing sugar while maintaining product texture. In this work, rheological properties of 0.1, 0.5 and 1 g/100 g guar solutions containing 10 and 40 g/100 g of maltitol, sorbitol, or xylitol were studied. The behavior of these mixtures was evaluated by steady and oscillatory shear measurements, and after a freezing/thawing cycle. Apparent viscosity of guar solutions increased with addition of polyols and with the increase in their concentrations, except for 40 g/100 g sorbitol addition to 1 g/100 g guar gum, in which the apparent viscosity decreased. Addition of polyols also increased the dynamic moduli of the systems. In mixtures of guar with 40 g/100 g polyol, the phase angle (δ) was below unity, but was dependent on frequency, which is characteristic of concentrated solutions with a certain degree of structuring. FTIR spectroscopy was studied to provide information on possible interactions between guar gum and polyols. Analyses carried out after freezing/thawing showed no changes in the viscoelastic behavior of the solutions. © 2013 Elsevier Ltd.

Diagnóstico da cadeia produtiva de rochas ornamentais e de revestimento do Estado do Ceará: mineração, serrarias, marmorarias e desafios do setor

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

A gestão do conhecimento em pequenas e médias empresas: um estudo de caso

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Contratistas, cambios tecnológicos y organizacionales en el agro argentino

Hasta no hace muchos años, en Argentina, la tenencia de la tierra era casi una condición suficiente para la producción agrícola. En los últimos años, el crecimiento en las cantidades obtenidas de granos, se ha dado en el contexto de una nueva forma de organización, donde son muy importantes otros factores productivos (capital –maquinarias-, capacidad empresarial), nuevos insumos (semillas transgénicas, nuevos agroquímicos y fertilizantes) y donde la tecnología que ambos tienen incorporada se potencia en agentes que acumularon un importante stock de conocimiento tácito. Más que por quién usa la tierra, el eje pasa por cómo la misma se utiliza. Los cambios tecnológicos y organizacionales tienen mucho que ver en la expansión agrícola argentina de las últimas décadas. Relacionado con estos factores e insumos, se destacan nuevos y remozados actores que, en conjunto con los productores y los eslabonamientos con la industria y los servicios, conforman y trabajan en forma de red (Bisang y Kosacoff, 2006). Como aporte a la descripción de este fenómeno, el objetivo de este trabajo es estudiar uno de esos protagonistas: los prestadores de servicios o contratistas. Se plantea como hipótesis que los cambios tecnológicos evidenciados en el agro fueron, en parte, canalizados hacia los productores por un actor (contratistas) que, especializado en la tenencia de un factor productivo (maquinaria), conjuga capacidad empresarial y financiera, necesidad por aplicar los cambios tecnológicos junto con conocimiento tácito, mayor posibilidad de diversificar el riesgo agropecuario y estrechas relaciones con el resto de los actores (dueños de la tierra, Centro de Servicios, etc.). A lo largo del trabajo se resume la interacción histórica entre los contratistas y la agricultura como una forma de caracterizar a estos empresarios y resaltar los aspectos que han influido en su expansión, convirtiéndolos en una peculiaridad de la agricultura argentina. Este repaso ofrece claros indicios sobre la hipótesis planteada -luego confirmados con información estadística- que, además, permite medir el peso de estos actores en la economía y su evolución reciente.

Adubação foliar de sulfato de zinco na produtividade e teores foliares de zinco e fosforo de cafeeiros arábica

Aiming to evaluate the dose and application schedule of foliar Zn-sulfate spraying in growing and yield of Arabic coffee Mundo Novo, a field experiment was set up on Distroferric Red Latosol, at the Experimental Station of the EPAMIG in São Sebastião do Paraíso. The statistical design used was randomized blocks in s 4 x 2 factorial scheme with five replications and a 30-plant plot with six central valid or four applications per agricultural year. Phosphorus and zinc leaf levels were evaluated for eight years and the yields. It was possible to conclude that there is a positive response to the in the leaves. Four low concentrations sprayings promoted higher yields than two high concentrations. The highest yields were achieved with 10.8 and 12.6 kg ha-1 of ZnSO4 and 4 yearly applications, respectively. It is suggested as a critical range for the Zn leaves values between 10 and 28 mg kg-1 and for P/Zn ratio, between 100 and 150. ) was sprayed under 4 concentrations 0; 0.5; 1.0 and 1.5%, two applied on the leaves in terms of yield, and to Zn levels

O arranjo produtivo local dos construtores de barcos artesanais: fundamentos para o desenvolvimento endógeno do Baixo - Tocantins (PA)

Este trabalho é um estudo de caso do Arranjo Produtivo Local – APL da indústria da construção naval artesanal no município de Igarapé-Miri região do Baixo – Tocantins. Atividade esta formado por estaleiros gerenciados por mestres trabalhadores detentores de um acervo intelectual tácito, passado de geração em geração. Objetiva investigar o potencial do APL da construção naval artesanal como fundamento do desenvolvimento endógeno na região. Deste modo, se analisou suas principais características, estrutura de produção, custo, ocupação, mercado e emprego nas pequenas empresas do APL da indústria naval bem como a dinâmica e a potencialidade do setor, os seus principais problemas e os entraves ao seu desenvolvimento. Dessa forma, a pesquisa constatou a crescente produção por tonelagem da indústria naval e os atores econômicos, políticos e sociais que dela tem se beneficiado. A pesquisa adotou o padrão metodológico das experiências de estudos de sistema de aprendizagem e inovações buscando entender sistemas e arranjos produtivos locais fundamentado na visão evolucionista sobre inovação e mudança tecnológica.