885 resultados para ISO 14067


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Tese de mestrado integrado em Engenharia da Energia e do Ambiente, apresentada à Universidade de Lisboa, através da Faculdade de Ciências, 2016

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The study of the Neogene (Miocene to Holocene) stratigraphic record on the glaciated Atlantic margin of NW Europe has, to date, largely been undertaken on an ad-hoc basis. Whereas a systematic approach to understanding the stratigraphic development of Palaeogene and older strata has been undertaken in areas such as the North Sea, West of Shetland and Norway, the problem of establishing a Neogene framework has been only partly addressed by academia and the oil industry. In most cases where a Neogene stratigraphy has been constructed, this has been largely in response to problem solving and risk assessment in a restricted area. Nevertheless, in the past few years it has become increasingly apparent that there is a common history in the Neogene development of the passive Atlantic margin of NW Europe, between mid-Norway and SW Ireland. The inspection and interpretation of an extensive geophysical and geological database has identified several regionally significant and correlatable unconformities along this continental margin. Thus, a regional approach to the stratigraphical development of the Neogene succession on the glaciated European Atlantic margin is undertaken in this volume.

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Includes bibliographical references.

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Thesis (doctoral)--Universität Basel, 1900.

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Thesis (doctoral)--Universitat Leipzig.

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The basis for the neuroprotectant effect of D-mannitol in reducing the sensory neurological disturbances seen in ciguatera poisoning, is unclear. Pacific ciguatoxin-1 (P-CTX-1), at a concentration 10 nM, caused a statistically significant swelling of rat sensory dorsal root ganglia (DRG) neurons that was reversed by hyperosmolar 50 MM D-mannitol. However, using electron paramagnetic resonance (EPR) spectroscopy, it was found that P-CTX-1 failed to generate hydroxyl free radicals at concentrations of toxin that caused profound effects on neuronal excitability. Whole-cell patch-clamp recordings from DRG neurons revealed that both hyper- and iso-osmolar 50 MM D-mannitol prevented the membrane depolarisation and repetitive firing of action potentials induced by P-CTX-1. In addition, both hyper- and iso-osmolar 50 MM D-mannitol prevented the hyperpolarising shift in steady-state inactivation and the rise in leakage current through tetrodotoxin (TTX)-sensitive Na-v channels, as well as the increased rate of recovery from inactivation of TTX-resistant Nav channels induced by P-CTX-1. D-Mannitol also reduced, but did not prevent, the inhibition of peak TTX-sensitive and TTX-resistant I-Na amplitude by P-CTX-1. Additional experiments using hyper- and isoosmolar D-sorbitol, hyperosmolar sucrose and the free radical scavenging agents Trolox (R) and L-ascorbic acid showed that these agents, unlike D-mannitol, failed to prevent the effects of P-CTX-1 on spike electrogenesis and Na-v channel gating. These selective actions of D-mannitol indicate that it does not act purely as an osmotic agent to reduce swelling of nerves, but involves a more complex action dependent on the Nav channel subtype, possibly to alter or reduce toxin association. (c) 2005 Elsevier Ltd. All rights reserved.

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The IRDS standard is an international standard produced by the International Organisation for Standardisation (ISO). In this work the process for producing standards in formal standards organisations, for example the ISO, and in more informal bodies, for example the Object Management Group (OMG), is examined. This thesis examines previous models and classifications of standards. The previous models and classifications are then combined to produce a new classification. The IRDS standard is then placed in a class in the new model as a reference anticipatory standard. Anticipatory standards are standards which are developed ahead of the technology in order to attempt to guide the market. The diffusion of the IRDS is traced over a period of eleven years. The economic conditions which affect the diffusion of standards are examined, particularly the economic conditions which prevail in compatibility markets such as the IT and ICT markets. Additionally the consequences of the introduction of gateway or converter devices into a market where a standard has not yet been established is examined. The IRDS standard did not have an installed base and this hindered its diffusion. The thesis concludes that the IRDS standard was overtaken by new developments such as object oriented technologies and middleware. This was partly because of the slow development process of developing standards in traditional organisations which operate on a consensus basis and partly because the IRDS standard did not have an installed base. Also the rise and proliferation of middleware products resulted in exchange mechanisms becoming dominant rather than repository solutions. The research method used in this work is a longitudinal study of the development and diffusion of the ISO/EEC IRDS standard. The research is regarded as a single case study and follows the interpretative epistemological point of view.

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This research aimed to identify any common factors that have enabled and/or motivated SMEs to successfully implement ISO 14001 whilst the majority have not. It also identified what challenges and barriers SMEs face in doing so and how some have overcome these. The existing literature suggests that the majority of SMEs perceive their environmental impacts to be proportional to their size; have a poor understanding of environmental issues; have a poor awareness of environmental regulations; do that have the necessary expertise or leadership to address environmental issues and that SMEs with an environmental management system such as ISO 14001 are very much the minority. The main factors that influenced whether an SME had implemented ISO 14001 were: competitive advantage, regulatory compliance, supply chain pressures, leadership, expertise, resources and external support. This research used qualitative analysis of interviews with managers and directors from 8 SMEs with ISO 14001 and 4 without. All of the SMEs were based in the West Midlands or Staffordshire. Interviews were also conducted with 3 organisations offering support to businesses on environmental issues and with 1 large business who was engaging their suppliers (which included SMEs within this sample) on environmental issues. The research found that there were four main factors that enabled or motivated the SMEs to implement ISO 14001, these were: leadership, supply chain pressures, external support and SMEs' history and experience of accredited management systems. The main challenges that these business had to overcome and that prevented the other SMEs from achieving ISO 14001 were: achieving regulatory compliance, perceived financial cost, lack of perceived competitive advantage, access to relevant and affordable support and for those SMEs without ISO 14001 there was very little perceived external pressure or need for them to do so.

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2002 Mathematics Subject Classification: 62P30, 62P10.

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The present dissertation aims to analyze the evaluation process of environmental performance inside an organization from the building construction section of civil construction based on the NBR ISO 14031 guidelines, which provide orientation regarding the implementation of this project towards the internal organizational management. The theoretical research has addressed concepts and historical development of environmental management inside organizations, from the emergence of the first models to the strengthening of environmental management through the standardization of the Environmental Management System caused by the publication of ISO 14001. It has also addressed the evaluation of environmental performance, the NBR ISO 14031 (concepts, types of indicators of evaluation of environmental performance, the elaboration process of such indicators, as well as its use and evaluation by the high administration). The research has an applied character, with exploratory and descriptive goals, and a qualitative approach based on case study. The data collection will be made through questionnaires, interviews, and documental analysis. Through the present research project, one expects to learn the elements taken into consideration by the organization for the elaboration and selection of indicators; to identify which interested parties contribute in the aforementioned process; to discover which sources are taken into consideration by the organization while establishing its environmental performance goals; to learn how the different kinds of environmental indicators are handled by organizations on daily basis, considering the existence of interferences on the decision making process, whether or not the interested parties are integrated, and if there is an periodical evaluation of environmental performance and how it is handled. One also expects to identify the opportunities for improvement regarding the organization that is object of study.

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O efeito conjugado das imposições da grande distribuição e dos consumidores cada vez mais exigentes levou os intervenientes do sector alimentar a considerarem a certificação dos seus produtos e/ou sistemas de produção por referenciais específicos. Todas as organizações que intervêm na cadeia alimentar têm a responsabilidade de colocar no mercado produtos alimentares cujas condições de higiene e segurança estejam devidamente garantidas. O trabalho desenvolvido no presente Projecto consistiu na preparação da implementação da norma NP EN ISSO 22000:2005 na empresa Cores Doces, Lda, dedicada ao comércio de doçaria. Tendo já o sistema HACCP implementado, a certificação através da norma de gestão da segurança alimentar NP EN ISSO 22000:2005 era um objetivo estratégico da administração da empresa uma vez que é este o referencial de segurança alimentar que melhor se adapta à realidade e objetivos da empresa e seus parceiros. O plano de trabalhos teve como objetivo fazer a transição entro o sistema HACCP (hazard Analysis and Critical Control Points) já implementado e certificado, para a implementação e certificação segundo os requisitos da norma NP EN ISSO 22000:2005. Para o efeito foram numa primeira fase identificadas as principais diferenças entre os dois sistemas de gestão da segurança alimentar. Esta análise permitiu diagnosticar as alterações processuais a implantar e os documentos a elaborar para a constituição da estrutura documental do sistema segundo a ISO 22000:2005. As principais alterações efetuadas foram a nível do Planeamento e Realização de Produtos Seguros, nomeadamente a análise de risco. Numa segunda fase foram apresentadas as alterações na empresa perante a transição para a ISSO onde se deu destaque aos aspetos relacionados com a responsabilidade da gestão, a compatibilização com os outros sistemas de gestão que possam ser criados na empresa (qualidade, ambiente, segurança e saúde); onde se fez igualmente a correspondência entre o Codex e a ISSO com destaque para o capítulo 7 na Norma ( Planeamento e Realização de Produtos Seguros), explorando os restantes capítulos que permitem introduzir na organização um ciclo de PDCA (Planear, Realizar, Avaliar e Corrigir). Finalmente foi elaborado um auxiliar de transição do sistema HACCP para a ISSO 22000 que possa servir de ferramenta para outras organizações.

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A qualidade está na base do sucesso no mundo empresarial, sendo um fator de competitividade e de diferenciação entre organizações. No contexto das Instituições Particulares de Solidariedade Social, a aposta na qualidade é também uma realidade. No entanto, estas instituições enfrentam diversas dificuldades no processo de implementação do sistema de gestão da qualidade (SGQ) ISO 9001. De entre estas, destaca-se o difícil acesso à metodologia, crenças impostas, culturas resistentes à mudança, desconhecimentos e receios, que resultam em custos avultados para as organizações, dado o recurso frequente a empresas de consultoria. Como tal, o presente trabalho de investigação pretende salientar as principais dificuldades no processo de implementação da norma ISO9001:2008 em IPSS e dar o seu contributo para a clarificação da polémica que envolve a certificação desta norma, mediante a criação de um kit, com todas as ferramentas necessárias à implementação da norma. Por conseguinte, e para dar resposta ao objetivo proposto, procedeu-se numa primeira instância à realização de inquéritos a 29 organizações certificadas pelas normas ISO 9001:2008 e/ou EQUASS (European Quality in Social Services), de forma a apreender as principais dificuldades no processo de implementação da norma nas várias IPSS. Esta análise permitiu concluir que, os principais fatores que dificultaram a implementação do sistema de gestão da qualidade, segundo a norma ISO 9001:2008, são essencialmente a falta de tempo e/ou disponibilidade, assim como a dificuldade de interpretação da norma. Como tal, as organizações necessitam de ferramentas de auxílio que as apoiem e esclareçam no processo de implementação do sistema da qualidade. Neste sentido, elaborou-se o kit de implementação “Qualifica”. Este é constituído por um manual e um CD interativo com documentos, formações e ferramentas para a implementação do sistema, cujo objetivo é esclarecer, encaminhar, orientar e simplificar todo o processo de implementação da norma e utilizando uma linguagem simples e acessível. Para finalizar, a viabilidade do KIT “Qualifica” foi devidamente validada através da sua aplicação numa IPSS não certificada. Após a revisão do sistema implementado na IPSS em estudo, conclui-se que o KIT "Qualifica" ofereceu todas as bases e todos os recursos necessários para o bom entendimento, encaminhamento e implementação da norma, provando a sua potencialidade como ferramenta auxiliar fundamental que qualquer organização poderá no futuro utilizar.