949 resultados para HADES – Hades Active Delay Evaluation System


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Artigo relativo a comunicação oral apresentada na 7.ª Conferência Luso-Brasileira de Acesso Aberto que decorreu de 2 a 4 de novembro em Viseu.

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La machine à vecteurs de support à une classe est un algorithme non-supervisé qui est capable d’apprendre une fonction de décision à partir de données d’une seule classe pour la détection d’anomalie. Avec les données d’entraînement d’une seule classe, elle peut identifier si une nouvelle donnée est similaire à l’ensemble d’entraînement. Dans ce mémoire, nous nous intéressons à la reconnaissance de forme de dynamique de frappe par la machine à vecteurs de support à une classe, pour l’authentification d’étudiants dans un système d’évaluation sommative à distance à l’Université Laval. Comme chaque étudiant à l’Université Laval possède un identifiant court, unique qu’il utilise pour tout accès sécurisé aux ressources informatiques, nous avons choisi cette chaîne de caractères comme support à la saisie de dynamique de frappe d’utilisateur pour construire notre propre base de données. Après avoir entraîné un modèle pour chaque étudiant avec ses données de dynamique de frappe, on veut pouvoir l’identifier et éventuellement détecter des imposteurs. Trois méthodes pour la classification ont été testées et discutées. Ainsi, nous avons pu constater les faiblesses de chaque méthode dans ce système. L’évaluation des taux de reconnaissance a permis de mettre en évidence leur dépendance au nombre de signatures ainsi qu’au nombre de caractères utilisés pour construire les signatures. Enfin, nous avons montré qu’il existe des corrélations entre le taux de reconnaissance et la dispersion dans les distributions des caractéristiques des signatures de dynamique de frappe.

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En este número de reflexiones pedagógicas presentamos el modelo que se ha diseñado para implementar la evaluación por colegas pares en la Universidad del Rosario. Explicamos los principios que lo guían y las etapas y procedimientos para realizar esta evaluación; además, exponemos algunos aprendizajes que ha dejado su implementación en dos facultades en los últimos años, y presentamos algunos retos y desarrollos que enfrenta el modelo a futuro.

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O sucesso de uma gestão baseada na estratégia reside, no aproveitamento racional e eficiente dos seus recursos humanos, financeiros e organizacionais, bem como na sua capacidade para concretizar objectivos e alcançar resultados. Esta dissertação foi elaborada baseando-se no pressuposto que, a selecção e a aplicação de um Instrumento de Apoio à Gestão em unidades privadas de fisioterapia (UPF’s) permitirão induzir níveis acrescidos de melhoria do desempenho individual e/ou organizacional. Constituiu objectivo geral da mesma contribuir para a sensibilização e a difusão alargada das ferramentas de apoio à gestão que, aplicadas naquelas unidades, poderiam induzir níveis acrescidos de melhoria do desempenho. Definiram-se ainda três objectivos específicos consubstanciando preocupações relacionadas com a reprodução do conhecimento especializado em gestão, com a sua aplicação específica no terreno e com a subjacente criação de valor individual e organizacional. A metodologia utilizada foi a abordagem de Estudo de Caso, inspirada na técnica focus-group, aplicada a três UPF’s, e os resultados obtidos através das análises efectuadas permitiram identificar a ausência da aplicação de instrumentos de apoio à gestão e de avaliação de desempenho, bem como níveis elevados de desempenho, satisfação e autonomia nos profissionais de fisioterapia, constituindo estes a base para justificar a necessidade urgente da elaboração de um plano de implementação de um sistema de avaliação de desempenho nas unidades estudadas. /ABSTRACT: The success of a management based on strategy relies in the rational and efficient use of its human, financial and organizational resources, as well as its ability to achieve objectives and results. This thesis was developed, based on the assumption that the selection and application of a management support instrument in private physiotherapy units would induce higher levels of individual performance and / or organization. It was general objective the contribution to the sensibilization and diffusion of tools to support management, which applied in those units, could induce higher levels of performance. There were defined three specific objectives which concerned whereabouts with the reproduction of specialized knowledge in management, with its specified applicability in the work field and with the underneath creation of individual and organizational value. The applied methodology was a case study, inspired by the focus-group technique applied in three private physiotherapy units, and the results obtained through the analysis allowed the identification of lack of use of any support management tools and performance evaluation, as well as high standard levels of performance, satisfaction and professional autonomy in physical therapists, being this the base for justifying the urgent need for developing an implementation plan of a performance evaluation system applied to these units.

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The objective of this study was to evaluate the effectiveness of a therapeutic sealant to arrest non-cavitated proximal carious lesion progression. The study population comprised 44 adolescents who had bitewing radiographs taken for caries diagnosis. Non-cavitated lesions extending up to half of dentin thickness were included in the sample. In the experimental group (n = 33), the proximal caries-lesion surfaces were sealed with an adhesive (OptiBond Solo, Kerr) after tooth separation. The control group (n = 11) received no treatment, except for oral hygiene instructions including use of dental floss. Follow-up radiographs were taken after one year and were analyzed in comparison with baseline radiographs. In a blind study setting, visual readings were performed by two examiners, blinded to whether the examined radiograph was baseline or follow-up, and whether it concerned a test or control lesion. The efficacy of sealing treatment was evaluated by the McNemar test (0.05). About 22% of the sealed lesions showed reduction, 61% showed no change and 16% showed progression. For the control lesions, the corresponding values were 27%, 36% and 36% respectively. The number of lesions that showed reduction and no changes were merged and therefore 83.3% of the sealed lesions and 63.6% of the control lesions were considered clinically successful. No statistical significance was detected (p > 0.05). In the course of 1 year, sealing proximal caries lesions was not shown to be superior to lesion monitoring.

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In the last decade, both scientific community and automotive industry enabled communications among vehicles in different kinds of scenarios proposing different vehicular architectures. Vehicular delay-tolerant networks (VDTNs) were proposed as a solution to overcome some of the issues found in other vehicular architectures, namely, in dispersed regions and emergency scenarios. Most of these issues arise from the unique characteristics of vehicular networks. Contrary to delay-tolerant networks (DTNs), VDTNs place the bundle layer under the network layer in order to simplify the layered architecture and enable communications in sparse regions characterized by long propagation delays, high error rates, and short contact durations. However, such characteristics turn contacts very important in order to exchange as much information as possible between nodes at every contact opportunity. One way to accomplish this goal is to enforce cooperation between network nodes. To promote cooperation among nodes, it is important that nodes share their own resources to deliver messages from others. This can be a very difficult task, if selfish nodes affect the performance of cooperative nodes. This paper studies the performance of a cooperative reputation system that detects, identify, and avoid communications with selfish nodes. Two scenarios were considered across all the experiments enforcing three different routing protocols (First Contact, Spray and Wait, and GeoSpray). For both scenarios, it was shown that reputation mechanisms that punish aggressively selfish nodes contribute to increase the overall network performance.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Considering that antioxidant flavonols have been reported to be beneficial to human health, but that their low water solubility and bioavailability limit their administration through systemic route, the development of suitable flavonol-carriers is of great importance for clinical therapeutics. The aim of this study was to prepare liposomes containing flavonols or not and evaluate their antioxidant activity. Vesicles were obtained by ethanol injection method and characterized in terms of entrapment efficiency, size and zeta potential. Inhibitory activity of liposomal flavonols on reactive oxygen species generation was assessed in vitro using luminol--H(2)O(2)--horseradish peroxidase technique. Antioxidant activity of liposomal flavonols is dependent on concentration and chemical structure of active compound. Quercetin and myricetin are the most active flavonols (IC(50) == 0.6--0.9 mu A mu mol/L), followed by kaempferol (IC(50) == 3.0--4.5 mu A mu mol/L) and galangin (IC(50) == 4.0--7.0 mu A mu mol/L). Our results suggest that antioxidant-loaded liposomes may be promising tools for therapy of diseases where oxidative stress is involved.

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Phenolic acids are aromatic secondary plant metabolites, widely spread throughout the plant kingdom. Due to their biological and pharmacological properties, they have been playing an important role in phytotherapy and consequently techniques for their separation and purification are in need. This thesis aims at exploring new sustainable separation processes based on ionic liquids (ILs) in the extraction of biologically active phenolic acids. For that purpose, three phenolic acids with similar chemical structures were selected: cinnamic acid, p-coumaric acid and caffeic acid. In the last years, it has been shown that ionic liquids-based aqueous biphasic systems (ABSs) are valid alternatives for the extraction, recovery and purification of biomolecules when compared to conventional ABS or extractions carried out with organic solvents. In particular, cholinium-based ILs represent a clear step towards a greener chemistry, while providing means for the implementation of efficient techniques for the separation and purification of biomolecules. In this work, ABSs were implemented using cholinium carboxylate ILs using either high charge density inorganic salt (K3PO4) or polyethylene glycol (PEG) to promote the phase separation of aqueous solutions containing three different phenolic acids. These systems allow for the evaluation of effect of chemical structure of the anion on the extraction efficiency. Only one imidazolium-based IL was used in order to establish the effect of the cation chemical structure. The selective extraction of one single acid was also researched. Overall, it was observed that phenolic acids display very complex behaviours in aqueous solutions, from dimerization to polymerization and also hetero-association are quite frequent phenomena, depending on the pH conditions. These phenomena greatly hinder the correct quantification of these acids in solution.

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Different compounds have been reported as biomarkers of a smoking habit, but, to date, there is no appropriate biomarker for tobacco-related exposure because the proposed chemicals seem to be nonspecific or they are only appropriate for short-term exposure. Moreover, conventional sampling methodologies require an invasive method because blood or urine samples are required. The use of a microtrap system coupled to gas chromatographymass spectrometry analysis has been found to be very effective for the noninvasive analysis of volatile organic compounds in breath samples. The levels of benzene, 2,5-dimethylfuran, toluene, o-xylene, and m- p-xylene have been analyzed in breath samples obtained from 204 volunteers (100 smokers, 104 nonsmokers; 147 females, 57 males; ages 16 to 53 years). 2,5-Dimethylfuran was always below the limit of detection (0.005 ppbv) in the nonsmoker population and always detected in smokers independently of the smoking habits. Benzene was only an effective biomarker for medium and heavy smokers, and its level was affected by smoking habits. Regarding the levels of xylenes and toluene, they were only different in heavy smokers and after short-term exposure. The results obtained suggest that 2,5-dimethylfuran is a specific breath biomarker of smoking status independently of the smoking habits (e.g., short- and long-term exposure, light and heavy consumption), and so this compound might be useful as a biomarker of smoking exposure

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Different compounds have been reported as biomarkers of a smoking habit, but, to date, there is no appropriate biomarker for tobacco-related exposure because the proposed chemicals seem to be nonspecific or they are only appropriate for short-term exposure. Moreover, conventional sampling methodologies require an invasive method because blood or urine samples are required. The use of a microtrap system coupled to gas chromatographymass spectrometry analysis has been found to be very effective for the noninvasive analysis of volatile organic compounds in breath samples. The levels of benzene, 2,5-dimethylfuran, toluene, o-xylene, and m- p-xylene have been analyzed in breath samples obtained from 204 volunteers (100 smokers, 104 nonsmokers; 147 females, 57 males; ages 16 to 53 years). 2,5-Dimethylfuran was always below the limit of detection (0.005 ppbv) in the nonsmoker population and always detected in smokers independently of the smoking habits. Benzene was only an effective biomarker for medium and heavy smokers, and its level was affected by smoking habits. Regarding the levels of xylenes and toluene, they were only different in heavy smokers and after short-term exposure. The results obtained suggest that 2,5-dimethylfuran is a specific breath biomarker of smoking status independently of the smoking habits (e.g., short- and long-term exposure, light and heavy consumption), and so this compound might be useful as a biomarker of smoking exposure

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The thesis entitled An Evaluation of Primary Health Care System in Kerala. The present study is intended to examine the working of primary health care system and its impact on the health status of people. The hypothesis tested in the thesis includes, a. The changes in the health profile require reallocation of resources of primary health care system, b. Rate of utilization depends on the quality of services provided by primary health centers, and c. There is a significant decline in the operational efficiency of the primary health care system. The major elements of primary health care stated in the report of AlmaAta International Conference on Primary Health Care (WHO, 1994)” is studied on the basis of the classification of the elements in to three: Preventive, Promotive, and Curative measures. Preventive measures include Maternal and Child Health Care including family Planning. Provision of water and sanitation is reviewed under promotive measures. Curative measures are studied using the disease profile of the study area. Collection of primary data was done through a sample survey, using pre-tested interview schedule of households of the study area. Multi stage random sampling design was used for selecting the sample. The design of the present study is both descriptive and analytical in nature. As far as the analytical tools are concerned, growth index, percentages, ratios, rates, time series analysis, analysis of variance, chi square test, Z test were used for analyzing the data. Present study revealed that no one in these areas was covered under any type of health insurance. Conclusion states that considering the present changes in the health profile, traditional pattern of resource allocation should be altered to meet the urgent health care needs of the people. Preventive and promotive measures like health education for giving awareness among people to change health habits, diet pattern, life style etc. are to be developed. Proper diagnosis and treatment of the disease at the beginning of the stage itself may help to cure majority of disease. For that, Public health policy must ensure the primary health care as enunciated at Alma- Ata international Conference. At the same time Public health is not to be treated as the sole responsibility of the government. Active community participation is an essential means to attain the goals.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)