School of Nursing Class of 1975

Top Row: Kris Aasvved, Phyllis Askew, Stephanie Babboni, Carolyn Backus, Carol Bockeloo, Veronica Banks, Patte Barland, Sally Barling, Rowena Beebe, Ginger Behr, Bobbi Bergmooser, Clary Bestor, Terry A. Bilinski, Debbie Blauer, Kathleen Bly, Lois K. Boer, Aurelia boyer, Polly Bradley, Sue Brenkert, Sherry Brezina

Row 2: Andrea Brown, Phyllis Buchholz, Michele Bujak, Barbara Burcham, Carol Burg, Mary Ann Campbell, Nancy Cartwright, Sally Chin, Kathleen Christmas, Barbara Clark, Marlene Clarkson, Alma Cole, Judy Coltson, Donna Craig, Janet L. Davies, Catherine Davidson, Sandra Detrisac, Toni Doherty, Kathleen Dumas, Deretha Eddings

Row 3: Marcia Ferrand, Karen Finger, Carol Fischer, Susan Fischer, Suzanne M. Fleszar, Barbara Fritz, Lola Garland, Susan Goldstein, Pam Goltz, Diane Gorman, Debby Goudreau, Diane Greenfield, Debbie Gross, Joan Hamman, Cheryl Hauch, Michelle Hays, Betty Henderson, Christena Henson, Constance Hill, Linda Hill

Row 4: Pamela Hill, Marilyn Holland, Patricia Horvath, Lois Huissen, Nance J. Huston, Phyllis Isackson, Angela Janik, Kim Johnson, Marjorie Kelsey, Wanda Kent, Eugenie Kimura, Lesley Kinnard, Kathleen Klute, Peggy Koskela, Linda Ksiazkiewicaz, Barbara Lang, Karen C. Carson, Kathryn Linder, Kathleen Lipinski, Janie Locke

Row 5: Nancy Luth, Denise Lyons, Susan Malkewitz, Diane Mannino, Nancy Marsh, Denise M. McCann, Carol McVannel, Vicky Melancon, Darlene Mikolajczak, Jane Monroe, Pam Morris, Cari Mulholland, Sandra Muller, Jacqueline Murphy, Terri Murtland, Colleen Nash, Debbie Nichols, Nancy Nowacek, Denise D. O'Brien, Sue Olejniczak

Row 6: Susan Panozzo, Marty Parmelee, Nancy Parr, Alexandra Paul, Pam Pennington, Patricia Phelps, Helen Piggush, Jan Pinkham, Molly Power, Janet Primeau, Ilona Proskie, Gretel Quitmeyer, Vicki Jo Ray, Josephine Reed, Ruth Riley, Norine Rowe, Beata Rudnik, Pat Rutowski, Linda Sanders, Patricia Saran

Row 7: Judy Sayles, Janis Schlicker, Janice Schmidt, Janiece Selecky, Deborah Silverman, Susan K. Smith, Theresa Sobanski, Marcia Sosnowski, Joyce Stein, Cathie Stepien, Pam Stoeffler, Sharon Swann, Susan Truchan, Susan Turke, Susan Valentine, Delores Vander Wal, Mary Jane VanLoon, Pamela A. Van Riper, Jeanne M. Wade, Karen Warner

Row 8: Deborah White, Rebecca E. Wildgen, Karen Williams, Sharon Williams, Debra Wilson, KEn Wilson, Nancy Wiltz, Maribeth Wooldridge, Martha Zawacki, JoAnn Zlotnick

Row 9: Julie Sochalski, Norma Shumaker, Kristin Brawner, Susan Archambault, Lauralee Hess, Rita M. Gibes, Barbara Terrien, Laurie Cushman, Mary Markey

Strange histories, of kings, princes, dukes, earles, lords, ladies, knights and gentlemen ...

Later published with title: The royal garland of delight.

The trail of the goldseekers : a record of travel in prose and verse /

Mode of access: Internet.

The North American Midwest, a regional geography.

Mode of access: Internet.

The eagle's heart.

Mode of access: Internet.

The Rose of Dutcher's Coolly /

Mode of access: Internet.

Serologic response to human papillomavirus 16 among Australian women with high-grade cervical intraepithelial neoplasia

This study evaluated the detection of human papillomavirus (HPV) 16 antibody in HPV 16-associated cervical intraepithelial neoplasia (CIN) in Australian women. Seroreactivity to HPV 16 L1 virus-like particles was assessed in patients with CIN 2 (n = 169) and CIN 3 (n = 229) lesions previously tested for the presence of HPV DNA. Seropositivity was significantly commoner in women with HPV 16 DNA-positive lesions (98/184) than in women with no HPV DNA in the lesion (15/47) or with HPV of types other than 16 in the lesion (43/167) (P = 0.0004). In addition, seropositivity was observed in 33% (55/169) of women with CIN 2 and 46% (106/229) of women with CIN 3, in keeping with the lower fraction of CIN 2 (57/169) than CIN 3 (127/229) biopsies positive for HPV 16 DNA. HPV 16 seropositivity is most common in women with HPV 16-associated CIN, but many patients with HPV-associated CIN 3 are seronegative, and HPV 16 seropositivity is common in women with CIN associated with other HPV types. Overall, HPV 16 serology is a poor predictor of presence of HPV 16-associated CIN 3 in patient population studied.

The effects of sway velocity on the triceps surae H-reflex during quiet standing

We have previously observed a change in the magnitude of the soleus (SOL) and medial gastrocnemius (MG) H-reflexes during different sway positions of quiet standing. The purpose of the present study was to extend the earlier finding by examining whether the SOL and MG H-reflexes are additionally influenced by the velocity of sway, i.e., whether the body is swaying in either the forward or backward direction. Five healthy subjects participated in the study. The mean position of the centre of pressure (COP) in the antero-posterior direction was determined while the subject stood quietly on a force plate for 60 s. In contrast to the earlier study, where the H-reflex was tested at the outermost positions of sway (±6 mm from the baseline mean), the current study elicited a SOL and MG H-reflex as the COP passed through the mean position of sway. This resulted in two sway conditions, where the position of the COP was the same but the sway velocity was different (10 mm s-1 forward and 10 mm s-1 backward). During the forward as compared to the backward velocity condition, there was a 20% and 25% increase in the amplitude of the H-reflex for the SOL and MG muscles, respectively, while the size of their respective background activities were the same. SOL and MG M-waves, as well as the level of background activity from the antagonist (tibialis anterior), were not different between the two sway conditions and thus cannot account for the observed changes to the amplitude of the H-reflexes. It can be concluded from these results that the direction (velocity) of sway has the ability to influence the size of the SOL and MG H-reflexes. The facilitation of the SOL and MG H-reflexes observed while swaying forward may be due to a reduction in presynaptic inhibition or an improvement in Ia synaptic efficacy brought about by changes in muscle length.

Non-peptidic antagonists of the CGRP receptor, BIBN4096BS and MK-0974, interact with the calcitonin receptor-like receptor via methionine-42 and RAMP1 via tryptophan-74

The receptor for calcitonin gene-related peptide (CGRP) has been the target for the development of novel small molecule antagonists for the treatment of migraine. Two such antagonists, BIBN4096BS and MK-0974, have shown great promise in clinical trials and hence a deeper understanding of the mechanism of their interaction with the receptor is now required. The structure of the CGRP receptor is unusual since it is comprised of a hetero-oligomeric complex between the calcitonin receptor-like receptor (CRL) and an accessory protein (RAMP1). Both the CLR and RAMP1 components have extracellular domains which interact with each other and together form part of the peptide-binding site. It seems likely that the antagonist binding site will also be located on the extracellular domains and indeed Trp-74 of RAMP1 has been shown to form part of the binding site for BIBN4096BS. However, despite a chimeric study demonstrating the role of the N-terminal domain of CLR in antagonist binding, no specific residues have been identified. Here we carry out a mutagenic screen of the extreme N-terminal domain of CLR (residues 23-63) and identify a mutant, Met-42-Ala, which displays 48-fold lower affinity for BIBN4096BS and almost 900-fold lower affinity for MK-0974. In addition, we confirm that the Trp-74-Lys mutation at human RAMP1 reduces BIBN4096BS affinity by over 300-fold and show for the first time a similar effect for MK-0974 affinity. The data suggest that the non-peptide antagonists occupy a binding site close to the interface of the N-terminal domains of CLR and RAMP1.

Efficacy, safety, and immunogenicity of the human papillomavirus 16/18 AS04-adjuvanted vaccine in women older than 25 years : 7-year follow-up of the phase 3, double-blind, randomised controlled VIVIANE study

Acknowledgments The VIVIANE study was funded and coordinated by GlaxoSmithKline Biologicals SA, which also covered all costs associated with development and publication of this report. We thank all study participants and their families. We gratefully acknowledge the work of the central and local study coordinators, and staff members of the sites who participated in this study. Writing support services were provided by Mary Greenacre (An Sgriobhadair, Isle of Barra, UK), on behalf of GSK Vaccines; editing and publication coordination services were provided by Jérôme Leemans (Keyrus Biopharma, Lasne, Belgium), Stéphanie Delval (XPE Pharma and Science, Wavre, Belgium), and Matthieu Depuydt (Business Decision Life Sciences, Brussels, Belgium), on behalf of GSK Vaccines

Italy in the Baroque: selected readings

Selected Italian texts written between 1583 and 1704 translated into English by Brendan Dooley.

Reciprocidades y gubernamentalidad tras la inserción del dispositivo religioso en cárceles de mediana y máxima seguridad de la provincia de Santa Fe (Argentina)

En el presente trabajo indagaremos sobre la reconfiguración de las dinámicas institucionales en dos cárceles de la provincia de Santa Fe, Argentina, tras la inserción del dispositivo religiosoevangélico- pentecostal. Los casos serán las penitenciarías n° 3 —mediana seguridad— y n° 11 — máxima seguridad—, y nos interrogaremos sobre las relaciones de reciprocidad que el dispositivo religioso configura en el encierro, en cómo dichas relaciones definen nuevas estrategias de gobierno por parte del servicio penitenciario y de qué manera se rediseñan las relaciones de poder en el dispositivo carcelario. Abordaje comparativo que responde a la hipótesis de que el dispositivo religioso-evangélicopentecostal construye matrices comunes de ordenamiento social, funcionamiento y reciprocidades en el encierro pero, al mismo tiempo, consolida su funcionamiento a raíz de una identificación precisa de las necesidades y oportunidades de los sujetos según atraviesen situaciones de ingreso o egreso carcelario.