301 resultados para Esteira rolante
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Pós-graduação em Medicina Veterinária - FCAV
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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The objective of this work is to perform a study applying the methodology of Reliability Centered Maintenance - MCC to a group of cranes belonging to Amsted -Maxion in Cruzeiro - SP. The work consists of a presentation of maintenance, the reasons why more and more people worry about maintenance, making a presentation on the types of maintenance, its peculiar characteristics and then do a study where you identified the functionality required by the equipment under study, identified failure modes and their probable causes, and then detail the effects and consequences of these failures. With that evaluate the criticality of these failures and identify the most significant consequences that affect safety, availability or cost of equipment operation and allow a selection of the most appropriate tasks for the identified failure modes. We will also present best crane equipment, its main components, verify that there was or not improvement in the machine after the application of MCC and make a current analysis of maintenance in Amsted -Maxion
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Este artículo tiene como objetivo presentar los supuestos básicos de la psicología histórico-cultural con el fin de aclarar sus contribuciones a la educación del campo. Esta teoría psicológica, cuya base filosófica es lo materialismo histórico-dialéctico, afirma el carácter social de la psique humana y la apropiación de signos como estera del desarrollo ilumina el papel indispensable de la educación escolar en la formación de los individuos. En este sentido, aborda los siguientes temas: historia y fundamentos filosóficos-metodológicos de la sicología histórico-cultural; diferenciación entre las propiedades psíquicas heredadas por la naturaleza (funciones síquicas básicas) y aquellas culturalmente formadas (funciones síquicas superiores); expresiones ontogenéticas de la producción y interiorización de la cultura; relaciones de intercondicionabilidad entre prácticas sociales y comportamientos complejos culturalmente formados. Como conclusión señala las alianzas entre la matriz psicológica resaltada y la pedagogía histórico-crítico, ya que para ambas teorías no son cualquiera modelo de educación escolar que apoyan la formación de las personas, sino más bien, una que les ofrece los contenidos culturales históricamente sistematizados y aprobados por la práctica social de todos los hombres.
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Pós-graduação em Fisiopatologia em Clínica Médica - FMB
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Pós-graduação em Estudos Literários - FCLAR
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Pós-graduação em Estudos Literários - FCLAR
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Dexamethasone (DEXA) is a synthetic glucocorticoid widely used in the handling of several drugs, for its proven benefits in fighting inflammation and allergies. Despite their benefits, their chronic use leads to several side effects that include changes in the body in the metabolism of carbohydrates, lipids and proteins. Moreover, being an anti-inflammatory, acts on the arachidonic acid pathway, reducing the expression of the enzyme cyclooxygenase (COX-2) and growth factor derived from the endothelium of blood vessels (VEGF) in various tissues. However, its effects on the myocardium are still uncertain. The physical training (PT), in turn, promotes effects contrary to those caused by chronic use of DEXA, however, little is known about the preventive effects of TF in the side effects of Dexa in the myocardium. Therefore, the aim of this study was to determine if the TF has the ability to prevent and/or mitigate the effects of Dexa in protein expression of COX-2 and VEGF in the myocardium. Forty animals were divided into 4 groups: sedentary control (SC), sedentary treated with Dexa (SD), trained control (TC) and Trained treated with Dexa (TD) and submitted to a protocol of physical training on the treadmill for 70 days (1 h/day-5 days per week, 60% of physical capacity) or kept sedentary. Over the past 10 days, rats were treated with Dexa (Decadron, 0.5 mg/kg per day, ip) or saline. During training the animals were weighed weekly and during treatment daily. At the end of treatment was made to measure fasting glucose levels of animals. The rats were killed with excess anesthesia and cardiac muscle was removed, weighed, homogenized, centrifuged and stored at -20° C for analysis of protein expression of VEGF and COX-2 by Western blotting technique. Treatment with dexamethasone caused a weight loss of 18% in sedentary animals and 13% in trained as well as elevated levels of fasting glucose in sedentary (88%). The TF was unable to mitigate the loss in...
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Muscle atrophy is always associated with Dexamethasone (Dexa) treatment, however the mechanisms are not completely understood. This study investigated the effects of Dexa on myostatin and p70S6K protein expression and if previous exercise training (T) can attenuate these effects. Eighty rats were distributed into 4 groups: sedentary control (SC), sedentary treated with Dexa (SD; 0,5 mg/kg per day, i.p., 10 days), trained control (TC) and trained treated with Dexa (TD) and underwent a training period where they were either submitted to a running protocol (60% of physical capacity, 5 days/week for 8 weeks) or kept sedentary. After T period, animals underwent Dexa treatment concomitant with training. Western Blot was performed to identify myostatin and p70S6k protein expression in the tibialis anterior (TA) and soleus (SOL) muscle. Ten days of Dexa treatment increased fasting glucose (SD=+62%), however previous T attenuated this increase (TD=+20%, p<0.05). Dexa determined significant decrease in body weight in TD (-22%) and SD (-25%), followed by TA weight reduction in SD (-23%) and TD (-20%). Previous training could not avoid these decreases. Myostatin protein expression was not altered by dexa treatment or training in TA muscle but in SOL muscle it was significantly modified after T, regardless of treatment (TC=+%23 and TD=+25) compared with their respective controls. The protein p70S6K was not modified neither by dexa nor training in any of the analyzed muscle or condition. The results of this study allowed us to conclude that previous training attenuates the hyperglycemia induced by Dexa, however it did not prevent the body or muscle weight reductions. Even in the presence of muscle atrophy, the expression of myostatin and p70S6K do not justify the mechanisms of muscle loss induced by Dexa, which suggests that other catabolic or anabolic proteins could be involved in the process of muscle atrophy after 10 days of treatment with Dexa