999 resultados para Bodenstedt, Friedrich Martin von, 1819-1892.


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UANL

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El presente trabajo trata de dar cuenta de explicar el proceso por el cual la medicina anatomoclínica configurada en Francia durante el siglo XVIII llega y se consolida en Chile durante 1833 a 1843. Par el desarrollo de este objetivo el trabajo consta de dos partes principales. En la primera parte se hace un estudio a profundidad sobre la configuración de la medicina anatomoclínica en Francia durante la Revolución Francesa. Esto nos permite entender que la constitución de esta medicina se da de la mano con la construcción del Estado Nacional francés y, así mismo, que este proceso se caracteriza por un cambio en la mentalidad de lo que significa la enfermedad y la manera en la que el oficio médico es entendido. La segunda parte es un estudio sobre cómo esta medicina llega a Chile y se consolida durante un periodo político particular en el que a la vez se institucionaliza la educación médica, se constituye un Estado Nación Chileno y se evidencia un cambio de los fundamentos de la medicina.

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Simulations of ozone loss rates using a three-dimensional chemical transport model and a box model during recent Antarctic and Arctic winters are compared with experimental loss rates. The study focused on the Antarctic winter 2003, during which the first Antarctic Match campaign was organized, and on Arctic winters 1999/2000, 2002/2003. The maximum ozone loss rates retrieved by the Match technique for the winters and levels studied reached 6 ppbv/sunlit hour and both types of simulations could generally reproduce the observations at 2-sigma error bar level. In some cases, for example, for the Arctic winter 2002/2003 at 475 K level, an excellent agreement within 1-sigma standard deviation level was obtained. An overestimation was also found with the box model simulation at some isentropic levels for the Antarctic winter and the Arctic winter 1999/2000, indicating an overestimation of chlorine activation in the model. Loss rates in the Antarctic show signs of saturation in September, which have to be considered in the comparison. Sensitivity tests were performed with the box model in order to assess the impact of kinetic parameters of the ClO-Cl2O2 catalytic cycle and total bromine content on the ozone loss rate. These tests resulted in a maximum change in ozone loss rates of 1.2 ppbv/sunlit hour, generally in high solar zenith angle conditions. In some cases, a better agreement was achieved with fastest photolysis of Cl2O2 and additional source of total inorganic bromine but at the expense of overestimation of smaller ozone loss rates derived later in the winter.

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The international circulation and reception of the works of Friedrich Carl von Savigny (1779-1861) constitute one of the main features of the first globalization of legal thought. Reaching law professors and practitioners from Brazil to Japan, readings of Savigny’s books offer a promising perspective for understanding how legal cultures around the world coped with the challenges of modernity. By focusing empirically on the circulation of books and analytically on the adaptation of texts to local contexts, the approach forwarded here tries to capture the creative aspects of the diffusion of knowledge. For this purpose, it concentrates on Brazilian readers of Savigny in the 19th Century, especially on the celebrated lawyer Augusto Teixeira de Freitas (1816-1883). It argues that Savigny’s works provided a decisive argumentative framework for some of the main issues discussed in Brazilian jurisprudence of the time. Freitas’ work documents a productive reading of Savigny that shaped his views on both normative and methodological issues, from slavery to codification. By tracing Freitas’ selective appropriation of Savigny’s texts, the article concludes that he was able both to reproduce and to subvert Savigny’s conception of private law, whenever the local context and his personal convictions demanded him to.

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Deutsche Forschungsgemeinschaft [SFB 840]

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O artigo discute a origem e a evolução dos conceitos de equilíbrio e tempo que Hicks utilizou para interpretar a Teoria Geral de Keynes. O trabalho está organizado em duas partes. Na primeira, analisaram-se os trabalhos de Hayek. Examinaram-se sua concepção de equilíbrio intertemporal e projeto de desenvolver uma teoria dos ciclos. Por último, discutiram-se a implementação desse projeto e seus problemas. Na segunda parte, foi examinado como Hicks, ao refletir sobre os problemas da teoria de Hayek, desenvolveu seus próprios conceitos de equilíbrio e tempo.

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Specialized pediatric cancer centers (PCCs) are thought to be essential to obtain state-of-the-art care for children and adolescents. We determined the proportion of childhood cancer patients not treated in a PCC, and described their characteristics and place of treatment.

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Only few studies considered demographic and medical characteristics of pain patients with depressive symptoms.

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Patient's language, tradition, conventions, and customs may all determine integration into a society and are also part of the doctor-patient relationship that influences diagnostic and therapeutic outcome. Language barrier and sociocultural disparity of Eastern and Southern European patients may hamper recovery from pain and depression compared to Middle European patients in Switzerland.

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Phosphatidylethanol (PEth) is a direct ethanol metabolite, and has recently attracted attention as biomarker of ethanol intake. The aims of the current study are: (1) to characterize the normalization time of PEth in larger samples than previously conducted; (2) to elucidate potential gender differences; and (3) to report the correlation of PEth with other biomarkers and self-reported alcohol consumption. Fifty-seven alcohol-dependent patients (ICD 10 F 10.25; 9 females, 48 males) entering medical detoxification at three study sites were enrolled. The study sample was comprised of 48 males and 9 females, with mean age 43.5. Mean gamma glutamyl transpeptidase (GGT) was 209.61 U/l, average mean corpuscular volume (MCV) was 97.35 fl, mean carbohydrate deficient transferrin (%CDT) was 8.68, and mean total ethanol intake in the last 7 days was 1653 g. PEth was measured in heparinized whole blood with a high-pressure liquid chromatography method, while GGT, MCV and %CDT were measured using routine methods. PEth levels at day 1 of detoxification ranged between 0.63 and 26.95 micromol/l (6.22 mean, 4.70 median, SD 4.97). There were no false negatives at day 1. Sensitivities for the other biomarkers were 40.4% for MCV, 73.1% for GGT and 69.2% for %CDT, respectively. No gender differences were found for PEth levels at any time point. Our data suggest that PEth is (1) a suitable intermediate term marker of ethanol intake in both sexes; and (2) sensitivity is extraordinary high in alcohol dependent patients. The results add further evidence to the data that suggest that PEth has potential as a candidate for a sensitive and specific biomarker, which reflects longer-lasting intake of higher amounts of alcohol and seemingly has the above mentioned certain advantages over traditional biomarkers.

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Introduction: As a previous study revealed, arts speech therapy (AST) affects cardiorespiratory interaction [1]. The aim of the present study was to investigate whether AST also has effects on brain oxygenation and hemodynamics measured non-invasively using near-infrared spectroscopy (NIRS). Material and methods: NIRS measurements were performed on 17 subjects (8 men and 9 women, mean age: 35.6 ± 12.7 y) during AST. Each measurement lasted 35 min, comprising 8 min pre-baseline, 10 min recitation and 20 min post-baseline. For each subject, measurements were performed for three different AST recitation tasks (recitation of alliterative, hexameter and prose verse). Relative concentration changes of oxyhemoglobin (Δ[O2Hb]) and deoxyhemoglobin (Δ[HHb]) as well as the tissue oxygenation index (TOI) were measured using a Hamamatsu NIRO300 NIRS device and a sensor placed on the subjects forehead. Movement artifacts were removed using a novel method [2]. Statistical analysis (Wilcoxon test) was applied to the data to investigate (i) if the recitation causes changes in the median values and/or in the Mayer wave power spectral density (MW-PSD, range: 0.07–0.13 Hz) of Δ[O2Hb], Δ[HHb] or TOI, and (ii) if these changes vary between the 3 recitation forms. Results: For all three recitation styles a significant (p < 0.05) decrease in Δ[O2Hb] and TOI was found, indicating a decrease in blood flow. These decreases did not vary significantly between the three styles. MW-PSD increased significantly for Δ[O2Hb] when reciting the hexameter and prose verse, and for Δ[HHb] and TOI when reciting alliterations and hexameter, representing an increase in Mayer waves. The MW-PSD increase for Δ[O2Hb] was significantly larger for the hexameter verse compared to alliterative and prose verse Conclusion: The study showed that AST affects brain hemodynamics (oxygenation, blood flow and Mayer waves). Recitation caused a significant decrease in cerebral blood flow for all recitation styles as well as an increase in Mayer waves, particularly for the hexameter, which may indicate a sympathetic activation. References 1. D. Cysarz, D. von Bonin, H. Lackner, P. Heusser, M. Moser, H. Bettermann. Am J Physiol Heart Circ Physiol, 287 (2) (2004), pp. H579–H587 2. F. Scholkmann, S. Spichtig, T. Muehlemann, M. Wolf. Physiol Meas, 31 (5) (2010), pp. 649–662

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