Limitaciones y fortalezas de la integración latinoamericana. Una visión desde las iniciativas del arco del pacífico latinoamericano y el acuerdo del pacífico. Periodo: 2007 - 2011

En la actualidad el Pacífico es visto como un espacio de oportunidades para aprovechar, bien sea de manera individual o a través de la creación de iniciativas comunes que conduzcan a mayores acercamientos a esta región. Si se apela a las iniciativas, es preciso estudiar el Acuerdo del Pacífico – AP, un espacio conformado por México, Colombia, Perú y Chile, que se plantea como principal objetivo el acercamiento a la región de Asia – Pacífico. Así, el presente documento intenta hacer un aporte a la disciplina de las Relaciones Internacionales por medio de un análisis de estas dos iniciativas, haciendo énfasis sobre el Acuerdo del Pacífico, también llamado Alianza del Pacífico, espacio que en la actualidad se perfila como uno de los de mayor dinamismo y relevancia en Latinoamérica.

Carpeta didáctica de educación afectivo sexual : educación secundaria 12-18. I.

Esta carpeta didáctica de educación secundaria contiene el siguiente material: 1. Guía didáctica del profesorado. 2. Cuadernos de experiencias ejemplificadoras. 3. Unidades didácticas: a) Somos seres sexuados. b) Desarrollo sexual. c) Fecundación, embarazo y parto. d) Anticoncepción y aborto. e) E.T.S. y SIDA. Con estos materiales se pretende contribuir a la educación integral de los alumnos y alumnas y a la construcción de una sociedad más saludable, desde una visión de la sexualidad como fuente de comunicación, afectividad y placer, y desde una concepción constructiva y participativa de los procesos de enseñanza y de aprendizaje.

Carpeta didáctica de educación afectivo sexual : educación secundaria 12-18. II.

Esta segunda carpeta didáctica de educación secundaria contiene el siguiente material: 1. Unidades didácticas: a) Relaciones interpersonales. b) Orientación del deseo. c) Respuesta sexual humanay disfunciones sexuales. d) Comercialización y violencia sexual. e) El sexismo en la sociedad actual. f) Ocio y tiempo libre. 2. Cada unidad didáctica contiene: a) Fichas de trabajo del alumnado. b) Documentos del profesorado. c) Contenidos básicos. d) Novela.

LARGE-SCALE DISTRIBUTION OF ARRIVAL DIRECTIONS OF COSMIC RAYS DETECTED ABOVE 10(18) eV AT THE PIERRE AUGER OBSERVATORY

A thorough search for large-scale anisotropies in the distribution of arrival directions of cosmic rays detected above 10(18) eV at the Pierre Auger Observatory is presented. This search is performed as a function of both declination and right ascension in several energy ranges above 10(18) eV, and reported in terms of dipolar and quadrupolar coefficients. Within the systematic uncertainties, no significant deviation from isotropy is revealed. Assuming that any cosmic-ray anisotropy is dominated by dipole and quadrupole moments in this energy range, upper limits on their amplitudes are derived. These upper limits allow us to test the origin of cosmic rays above 10(18) eV from stationary Galactic sources densely distributed in the Galactic disk and predominantly emitting light particles in all directions.

Constraints on the origin of cosmics rays above '10 POT. 18' eV from large-scale anisotropy searches in data of the Pierre Auger observatory

A thorough search for large-scale anisotropies in the distribution of arrival directions of cosmic rays detected above '10 POT. 18' eV at the Pierre Auger Observatory is reported. For the first time, these large-scale anisotropy searches are performed as a function of both the right ascension and the declination and expressed in terms of dipole and quadrupole moments.Within the systematic uncertainties, no significant deviation from isotropy is revealed. Upper limits on dipole and quadrupole amplitudes are derived under the hypothesis that any cosmic ray anisotropy is dominated by such moments in this energy range. These upper limits provide constraints on the production of cosmic rays above '10 POT. 18' eV, since they allow us to challenge an origin from stationary galactic sources densely distributed in the galactic disk and emitting predominantly light particles in all directions.

Changes in bone mineral density over 18 months following kidney transplantation: the respective roles of prednisone and parathyroid hormone

Prednisone is a major factor of bone loss after kidney transplantation. The role of hyperparathyroidism and immunosuppressors is less clear.

Comparative effects of Teriparatide and Risedronate in glucocorticoid‐induced osteoporosis in men: 18‐month results of the EuroGIOPs trial

Data on treatment of glucocorticoid-induced osteoporosis (GIO) in men are scarce. We performed a randomized, open-label trial in men who have taken glucocorticoids (GC) for ≥3 months, and had an areal bone mineral density (aBMD) T-score ≤ –1.5 standard deviations. Subjects received 20 μg/d teriparatide (n = 45) or 35 mg/week risedronate (n = 47) for 18 months. Primary objective was to compare lumbar spine (L1–L3) BMD measured by quantitative computed tomography (QCT). Secondary outcomes included BMD and microstructure measured by high-resolution QCT (HRQCT) at the 12th thoracic vertebra, biomechanical effects for axial compression, anterior bending, and axial torsion evaluated by finite element (FE) analysis from HRQCT data, aBMD by dual X-ray absorptiometry, biochemical markers, and safety. Computed tomography scans were performed at 0, 6, and 18 months. A mixed model repeated measures analysis was performed to compare changes from baseline between groups. Mean age was 56.3 years. Median GC dose and duration were 8.8 mg/d and 6.4 years, respectively; 39.1% of subjects had a prevalent fracture, and 32.6% received prior bisphosphonate treatment. At 18 months, trabecular BMD had significantly increased for both treatments, with significantly greater increases with teriparatide (16.3% versus 3.8%; p = 0.004). HRQCT trabecular and cortical variables significantly increased for both treatments with significantly larger improvements for teriparatide for integral and trabecular BMD and bone surface to volume ratio (BS/BV) as a microstructural measure. Vertebral strength increases at 18 months were significant in both groups (teriparatide: 26.0% to 34.0%; risedronate: 4.2% to 6.7%), with significantly higher increases in the teriparatide group for all loading modes (0.005 < p < 0.015). Adverse events were similar between groups. None of the patients on teriparatide but five (10.6%) on risedronate developed new clinical fractures (p = 0.056). In conclusion, in this 18-month trial in men with GIO, teriparatide showed larger improvements in spinal BMD, microstructure, and FE-derived strength than risedronate.