Desarrollo de aplicación para dispositivo móvil : GESMED

Desarrollo de aplicación para dispositivo móvil en plataforma Android de gestión básica de servicios médicos.

Sistema de controlo e reservas de salas da Universidade do Mindelo

Este trabalho tem como objetivo apresentar um projeto para o desenvolvimento de um sistema de informação web, visando automatizar o processo de controlo de reservas de salas da Universidade do Mindelo. O acesso ao sistema será feito através do site da Universidade onde os utilizadores poderão cadastrar, controlar, reservar e consultar o uso das salas da Universidade. Além disso, através do uso de padrões de projetos e de conceitos da engenharia e arquitetura de software, este trabalho tem por objetivo a construção do sistema através da tecnologia PHP – Personal Home Page e Javascript. As tecnologias utilizadas para o desenvolvimento do sistema são gratuitas, tais como, servidor web Apache, base de dados MySQL, Microsoft Office Visio, DBDesigner, Toad for MySQL, sendo portáveis para qualquer sistema operativo, como: Linux, Windows, entre outros.

ProyGes : soporte de gestión de proyectos

La aplicación tiene como objetivo llegar a la comunidad de alumnos, los cuales no pueden tener reuniones presenciales debido a su situación geográfica. La aplicación dispone de un conjunto de herramientas para poder centralizar toda la información que los usuarios vayan generando durante el desarrollo de los proyectos. Ha de ser una herramienta para facilitar la organización y la administración de los recursos de los usuarios de la plataforma. El proyecto que se presenta es una aplicación web, desarrollada en lenguajes PHP, SQL, HTML, JavaScript, CSS, Ajax, en un servidor Apache y base de datos MySQL.

Creació de cartelleria via web

Projecte d'aplicació real de generació i impressió de cartelleria. Encara que el seu disseny s'ha fet de la manera més general possible, la finalitat d'aquest és que sigui funcional.

Twenty-eight days and long term survival after severe sepsis and septic shock in adults

Résumé : Nous avons effectué une étude de cohorte examinant la survie de tous les patients qui ont présenté une sepsis sévère ou un choc septique aux soins intensifs de médecine et de chirurgie du CIIUV durant une période de 3 ans. Introduction: La sepsis sévère et le choc septique constituent la deuxième cause de mortalité dans les unités de soins intensifs non coronaires. La survie à long terme est mal connue. Nous avons comparé la survie à 28 jours de notre collectif avec les données de la littérature, examiné la survie à long terme des patients ayant survécus plus de 28 jours et identifié des paramètres prédictifs de la survie. Matériel et méthode : Nous avons classifié les patients ayant présenté un épisode septique rétrospectivement en sepsis sévère ou choc septique selon les critères de Bone (1). Les données cliniques et paracliniques ont été relevées au moment de l'épisode. Des courbes de survie uni- et multivariées ont été établies à 28 jours et à long terme chez ceux qui ont survécus plus de 28 jours, d'après les données de questionnaires envoyés aux médecins traitants. Résultats : Durant Ìa période de l'étude, 339 patients ont présenté un choc septique (169) ou une sepsis sévère (170). La mortalité à 28 jours a été de 33% (choc septique: 55%, sepsis sévère: 11.2%, p<10"5). Les données significativement associées à la mortalité à 28 jours dans l'analyse de régression multivariée selon Cox ont été le type d'épisode septique (choc septique vs. sepsis sévère, p=0.001), le «Acute Physiology Score» du score APACHE II (p=0.02) et le nombre de dysfonctions d'organes (plus de trois dysfunctions, p=0.04). 227 patients ont survécu plus de 28 jours et des données de suivi ont été obtenues chez 225. Le suivi moyen après 28 jours a été de 25.1 mois (5700 mois-patients). La mortalité globale de ces patients, extrapolée des courbes de Kaplan-Meyer, a été de l'ordre de 7% à 1 an et de 15% à 2 ans. Les données significativement associées à leur survie à long terme ont été les "chronic health points" du score APACHE II (p=0.02), l'âge (p=0.05) et le fait d'avoir subi une opération chirurgicale avant l'épisode septique (p=0.02). Conclusion : La mortalité à 28 jours de notre cohorte de patients s'est révélée comparable aux chiffres publiés. La survie à long terme des patients ayant survécu plus de 28 jours a été satisfaisante. Elle s'est révélée indépendante de la sévérité de l'épisode septique, mais dépendait plutôt des conditions de santé sous-jacentes.

Sistemas de Informação WEB para gestão de stock

Este projecto consiste no desenvolvimento de um Sistema de Informação Web para Gestão de Stock e que funciona também em um ambiente sem internet. O mesmo faz a entrada de stock, venda, devolução de clientes, lança os produtos deteriorados, no fim de cada dia faz o fecho de caixa, resumo de vendas, resumo das entradas de stock, resumo dos produtos deteriorados, resumo de fecho de caixa, inventário, registo de funcionário, registo de fornecedor, registo de artigo, backup periodicamente e disponibilizando ao gerente informações rápidas sobre seu stock e estatísticas de vendas. Com o sistema em funcionamento pretende-se garantir transações rápidas e eficientes entre funcionários, clientes e o gerente. È muito importante dizer que o sistema tem um funcionamento muito simples e foi implementado a pensar nas micro e pequenas empresas, visto que é um sector que se encontra em pleno desenvolvimento em Cabo Verde e que nos dias de hoje é obrigatório ter um software de gestão para que o Ministério das Finanças possa ter maior controlo sobre os resultados das empresas. Para o desenvolvimento do sistema (Simple Gest), utilizei um servidor web (Apache), servidor de base de dados (MySQL), interpretadores para linguagem de script PHP fornecidos através da ferramenta XAMPP (servidor independente de plataforma), a linguagem de programação PHP para fazer a conecção entre o sistema e a base de dados, HTML para criar e apresentar as páginas na web, CSS para dar estilo as páginas através de um browser e UML para a modelação dos dados. Na análise do sistema foram identificados os requisitos funcionais e os requisitos não funcionais, foram desenvolvidos os casos de usos necessários, os diagramas de casos de uso, diagramas de sequência e o modelo entidade-relacionamento para demonstrar o fluxo de dados.

Brain Tissue Hypoxia is a Strong Predictor of Outcome after Severe Traumatic Brain Injury Independent from Elevated Intracranial Pressure

Introduction: Low brain tissue oxygen pressure (PbtO2) is associated with worse outcome in patients with severe traumatic brain injury (TBI). However, it is unclear whether brain tissue hypoxia is merely a marker of injury severity or a predictor of prognosis, independent from intracranial pressure (ICP) and injury severity. Hypothesis: We hypothesized that brain tissue hypoxia was an independent predictor of outcome in patients wih severe TBI, irrespective of elevated ICP and of the severity of cerebral and systemic injury. Methods: This observational study was conducted at the Neurological ICU, Hospital of the University of Pennsylvania, an academic level I trauma center. Patients admitted with severe TBI who had PbtO2 and ICP monitoring were included in the study. PbtO2, ICP, mean arterial pressure (MAP) and cerebral perfusion pressure (CPP = MAP-ICP) were monitored continuously and recorded prospectively every 30 min. Using linear interpolation, duration and cumulative dose (area under the curve, AUC) of brain tissue hypoxia (PbtO2 < 15 mm Hg), elevated ICP >20 mm Hg and low CPP <60 mm Hg were calculated, and the association with outcome at hospital discharge, dichotomized as good (Glasgow Outcome Score [GOS] 4-5) vs. poor (GOS 1-3), was analyzed. Results: A total of 103 consecutive patients, monitored for an average of 5 days, was studied. Brain tissue hypoxia was observed in 66 (64%) patients despite ICP was < 20 mm Hg and CPP > 60 mm Hg (72 +/- 39% and 49 +/- 41% of brain hypoxic time, respectively). Compared with patients with good outcome, those with poor outcome had a longer duration of brain hypoxia (1.7 +/- 3.7 vs. 8.3 +/- 15.9 hrs, P<0.01), as well as a longer duration (11.5 +/- 16.5 vs. 21.6 +/- 29.6 hrs, P=0.03) and a greater cumulative dose (56 +/- 93 vs. 143 +/- 218 mm Hg*hrs, P<0.01) of elevated ICP. By multivariable logistic regression, admission Glasgow Coma Scale (OR, 0.83, 95% CI: 0.70-0.99, P=0.04), Marshall CT score (OR 2.42, 95% CI: 1.42-4.11, P<0.01), APACHE II (OR 1.20, 95% CI: 1.03-1.43, P=0.03), and the duration of brain tissue hypoxia (OR 1.13; 95% CI: 1.01-1.27; P=0.04) were all significantly associated with poor outcome. No independent association was found between the AUC for elevated ICP and outcome (OR 1.01, 95% CI 0.97-1.02, P=0.11) in our prospective cohort. Conclusions: In patients with severe TBI, brain tissue hypoxia is frequent, despite normal ICP and CPP, and is associated with poor outcome, independent of intracranial hypertension and the severity of cerebral and systemic injury. Our findings indicate that PbtO2 is a strong physiologic prognostic marker after TBI. Further study is warranted to examine whether PbtO2-directed therapy improves outcome in severely head-injured patients .

Anemia and brain oxygen after severe traumatic brain injury.

PURPOSE: To investigate the relationship between hemoglobin (Hgb) and brain tissue oxygen tension (PbtO(2)) after severe traumatic brain injury (TBI) and to examine its impact on outcome. METHODS: This was a retrospective analysis of a prospective cohort of severe TBI patients whose PbtO(2) was monitored. The relationship between Hgb-categorized into four quartiles (≤9; 9-10; 10.1-11; >11 g/dl)-and PbtO(2) was analyzed using mixed-effects models. Anemia with compromised PbtO(2) was defined as episodes of Hgb ≤ 9 g/dl with simultaneous PbtO(2) < 20 mmHg. Outcome was assessed at 30 days using the Glasgow outcome score (GOS), dichotomized as favorable (GOS 4-5) vs. unfavorable (GOS 1-3). RESULTS: We analyzed 474 simultaneous Hgb and PbtO(2) samples from 80 patients (mean age 44 ± 20 years, median GCS 4 (3-7)). Using Hgb > 11 g/dl as the reference level, and controlling for important physiologic covariates (CPP, PaO(2), PaCO(2)), Hgb ≤ 9 g/dl was the only Hgb level that was associated with lower PbtO(2) (coefficient -6.53 (95 % CI -9.13; -3.94), p < 0.001). Anemia with simultaneous PbtO(2) < 20 mmHg, but not anemia alone, increased the risk of unfavorable outcome (odds ratio 6.24 (95 % CI 1.61; 24.22), p = 0.008), controlling for age, GCS, Marshall CT grade, and APACHE II score. CONCLUSIONS: In this cohort of severe TBI patients whose PbtO(2) was monitored, a Hgb level no greater than 9 g/dl was associated with compromised PbtO(2). Anemia with simultaneous compromised PbtO(2), but not anemia alone, was a risk factor for unfavorable outcome, irrespective of injury severity.

Brachiaria species affecting soil nitrification

Nitrification can lead to substantial losses of the applied N through nitrate leaching and N2O emission. The regulation of nitrification may be a strategy to improve fertilizer N recovery and increase its agronomic efficiency. The objective of this study was to evaluate the inhibiting capacity of nitrification in soil by Brachiaria species. The greenhouse experiment was conducted using pots with 10 dm³ of a Red Latosol sample. The treatments consisted of the cultivation of three forage species (Brachiaria brizantha, B. ruziziensis and B. decumbens) and four n rates (0, 100, 200, and 300 mg/pot), and the control (without plants). In the absence of the forage plants, all N fertilization levels raised the N-NO3- soil levels, as a result of nitrification. The mineralization of organic matter supplied much of the N requirement of the forage plants and nitrification was influenced in the rhizosphere of B. brizantha; however, this effect was not high enough to alter the N-NH4+ level in the total soil volume of the pot.

Produtividade e qualidade dos grãos de feijão em função da aplicação de nitrogênio em cobertura e via foliar

A adequada disponibilidade de N durante do ciclo do feijoeiro é fundamental para garantir elevada produtividade e qualidade dos grãos produzidos. Esse nutriente pode ser absorvido pelas raízes e folhas da planta. Contudo, ainda existem dúvidas sobre a eficiência da aplicação via foliar de N no feijoeiro e sobre a influência dessa prática na qualidade dos grãos. Objetivou-se neste trabalho avaliar o efeito da adubação nitrogenada em cobertura e via foliar sobre a produtividade e qualidade dos grãos da cultura do feijão. O experimento foi conduzido durante a safra "da seca", em um Latossolo Vermelho distroférrico, no município de Botucatu-SP. O delineamento experimental utilizado foi o de blocos ao acaso com quatro repetições, num esquema fatorial 3 x 4, constituído por três doses de N (0, 45 e 90 kg ha-1) em cobertura e quatro épocas de aplicação de N via foliar (1 - sem aplicação de N via foliar, 2 - pulverização estádio R5 (pré-floração), 3 - pulverização no estádio R7 (início da formação das vagens) e 4 - pulverizações nos estádios R5 e R7). Em cada aplicação de N via foliar foram utilizados 200 L ha-1 de uma solução com 10 % de ureia. Quando foi realizada a adubação nitrogenada de cobertura, a aplicação de N via foliar, independentemente da época, não alterou os componentes da produção, a produtividade e a qualidade dos grãos do feijoeiro. Na ausência da adubação nitrogenada de cobertura, a aplicação de N via foliar na fase reprodutiva aumentou a massa e o tamanho dos grãos, a produtividade de grãos e o teor de proteínas nos grãos do feijoeiro. A aplicação de N via foliar no estádio R5 foi mais eficiente em aumentar a produtividade de grãos do feijoeiro que a aplicação em R7.

Effect of fertilization at sowing on nutrition and yield of crambe in second season

The interest in crambe (Crambe abyssinica ) cultivation in Brazil is on the rise, whereas information on the nutrient requirements for this crop is scarce. The objective of this work was to evaluate the effect of nitrogen-phosphorus-potassium (N-P2O5-K2O formula 8:28:16) fertilization (0, 150, and 300 kg ha-1) on crambe shoot biomass production, grain and oil yields, and nutrient extraction and exportation in the second growing season after soybean. The experiment with a Haplorthox (Dystroferric Red Latosol) was carried out for two years in Botucatu, São Paulo State, Brazil. A randomized complete block design with eight replications was used. Fertilization with NPK at sowing increased the shoot biomass production, grain yield, grain oil content, as well as nutrient extraction and exportation at harvest. In the fertilized treatments, the average amounts of nutrients extracted per hectare were 91 kg K, 71 kg N, 52 kg Ca, 9.4 kg P, 9.4 kg Mg, 7.9 kg S, 2,348 g Fe, 289 g Zn, 135 g Mn, and 18.2 g Cu; while the average values of nutrient exportation per hectare were 54 kg N, 20 kg K, 12.3 kg Ca, 10 kg P, 6.6 kg S, 3.2 kg Mg, 365 g Zn, 60 g Fe, 50 g Mn, and 7.3 g Cu, with NPK fertilizer application.

Panobacumab adjunctive immuno-therapy for Pseudomonas aeruginosa hospital-acquired pneumonia versus a cohort group

Objectives: To assess the efficacy of Panobacumab, a fully human IgM monoclonal antibody against P. aeruginosa serotype O11, by comparing a phase IIa trial with a standard care cohort trial both in hospital acquired pneumonia (HAP) caused by P. aeruginosa O11. Methods: Demographics, outcome and survival of HAP including Ventilator Associated Pneumonia (VAP) in patients either treated with standard antimicrobial therapy in a retrospective cohort trial (CT) or with adjunctive Panobacumab therapy during an open phase IIa trial were compared. Both trials applied the same inclusion exclusion criteria and the same trial period of 30 days. Results: 17 patients with VAP/HAP (14 / 3) caused by P. aeruginosa O11 were enrolled in a phase IIa trial (ITT population) and treated with Panobacumab, 13 of them received the full treatment course of 3 infusions (PP population, 12 VAP, 1 HAP) and 4 patients received only one infusion. In the cohort trial 14 patients (VAP/HAP: 12 / 2) treated with standard antibiotic therapy were included. The mean age and weight were 65.8 y (years) (SD 17.2) and 78.0 kg (SD 22.1) in the PP, 67.8 y (SD 15.4) and 77.1 kg (SD 20.2) in the ITT population and 51.8 y (SD 22.3) and 67.1 kg (SD 13.0) in the CT. At the time of suspicion of pneumonia a mean APACHE II and CPIS of 19.4 (13 - 33) and 8.7 (7 - 11) in the PP, 18.9 (13-33) and 8.5 (7 -11) in the ITT and 14.5 (2 - 24) and 7.5 (3 -12) in the CT population were observed. Tracheostomy was present in 53.8% and 52.9% in the PP and ITT populations and 38.4% in the CT. The pneumonia was polymicrobial in 69.2%, 70.6% and 85.7% in the PP, ITT and CT respectively. Stay at ICU and hospital before diagnosis of pneumonia were similar in the 3 groups. All 13 patients that received 3 doses of Panobacumab achieved resolution of pneumonia with only two relapsing during the study. Hence 85% achieved resolution and 15% recurrence at day 30. In the ITT group 64.7% of the pneumonia resolved 11.8% recurred and 23.5% continued while in the CT 57% resolved, 7% recurred and 34% continued. Resolution of pneumonia occurred markedly earlier in the Panobacumab trial (8.9 days, SD: 3.3) than in the cohort trial (15.3 days, SD: 9.5). The expected mortality derived from APACHE II score was 31% and 32% in the PP and ITT population and 22% in the cohort group. All patients who received 3 doses of Panobacumab survived, 18% died in the ITT group while in the CT 21% mortality matched the predicted mortality. Conclusions: Treatment of VAP/HAP caused by P. aeruginosa O11 with 3 doses of Panobacumab resulted in 100% survival, with highest pneumonia resolution (85%), and in a shorter time when compared with patients under standard therapy. The results indicate that Panobacumab may be effective in such life-threatening indication and warrants larger controlled trials.

Extração e exportação de nutrientes pelo feijoeiro adubado com nitrogênio, em diferentes tempos de implantação do sistema plantio direto

O cultivo do feijoeiro em sistema plantio direto (SPD) tem aumentado de forma marcante no país. Neste contexto, para adubações mais racionais, é fundamental conhecer as exigências nutricionais da cultura quando cultivada em SPD recém-implantado ou consolidado, já que o tempo de implantação do sistema pode alterar a disponibilidade de nutrientes e a resposta das culturas à adubação nitrogenada. Objetivou-se avaliar a extração e exportação de nutrientes pelo feijoeiro em razão da adubação nitrogenada, em solo sob SPD recém-implantado ou consolidado. O experimento foi conduzido por dois anos agrícolas, em um Nitossolo Vermelho distrófico, no município de Botucatu, SP. O delineamento experimental foi em blocos ao acaso, em esquema de parcelas subdivididas, com quatro repetições. As parcelas foram formadas por áreas sob SPD com diferentes tempos de adoção, e as subparcelas constituídas por quatro formas de aplicação do nitrogênio (N) na cultura do feijão (T0: controle, sem aplicação de N; T1: 60 kg ha-1 na pré-semeadura; T2: 60 kg ha-1 aplicado em cobertura no estádio V4; e T3: 60 kg ha-1 na pré-semeadura + 60 kg ha-1 em cobertura). Foram avaliados: matéria seca da parte aérea, concentração e acúmulo de nutrientes na parte aérea, produtividade de grãos e concentrações e exportação de nutrientes nos grãos. O tempo que a área permaneceu sob SPD não influenciou a produtividade, a nutrição e nem mesmo a resposta da cultura do feijão à adubação nitrogenada. A aplicação de N, especialmente em pré-semeadura, proporcionou maiores acúmulos de matéria seca e nutrientes pela cultura do feijão. As concentrações de nutrientes nos grãos foram pouco influenciadas pela adubação nitrogenada. As maiores produtividades de grãos e exportações de nutrientes foram proporcionadas pela aplicação de N em duas épocas (pré-semeadura e em cobertura) ou apenas em cobertura.

Pseudomonas aeruginosa serotypes in nosocomial pneumonia: prevalence and clinical outcomes.

INTRODUCTION: Pseudomonas aeruginosa frequently causes nosocomial pneumonia and is associated with poor outcome. The purpose of this study was to assess the prevalence and clinical outcome of nosocomial pneumonia caused by serotype-specific P. aeruginosa in critically ill patients under appropriate antimicrobial therapy management. METHODS: A retrospective, non-interventional epidemiological multicenter cohort study involving 143 patients with confirmed nosocomial pneumonia caused by P. aeruginosa. Patients were analyzed for a period of 30 days from time of nosocomial pneumonia onset. Fourteen patients fulfilling the same criteria from a phase IIa studyconducted at the same time/centers were included in the prevalence calculations but not in the clinical outcome analysis. RESULTS: The prevalence of serotypes was: O6 (29%), O11 (23%), O10 (10%), O2 (9%), and O1 (8%). Serotypes with a prevalence of less than 5% were found in 13% of patients, 8% were classified as not typeable. Across all serotypes, 19% mortality, 70% clinical resolution, 11% clinical continuation, and 5% clinical recurrence were recorded. Age and higher APACHE II (Acute Physiology and Chronic Health Evaluation II) were predictive risk factors associated with probability of death and lower clinical resolution for P. aeruginosa nosocomial pneumonia. Mortality tends to be higher with O1 (40%) and lower with O2 (0%); clinical resolution tends to be better with O2 (82%) compared to other serotypes. Persisting pneumonia with O6 and O11 was, respectively, 8% and 21%; clinical resolution with O6 and O11 was, respectively, 75% and 57%. CONCLUSIONS: In P. aeruginosa nosocomial pneumonia, the most prevalent serotypes were O6 and O11. Further studies including larger group sizes are needed to correlate clinical outcome with virulence factors of P. aeruginosa in patients with nosocomial pneumonia caused by various serotypes; and to compare O6 and O11, the two serotypes most frequently encountered in critically ill patients.

MyTopRoom : Aplicación para Android: Buscador de ofertas de hoteles

El objetivo de este proyecto es el desarrollo de una aplicación móvil para dispositivos con sistema operativo Android que permita la búsqueda de ofertas de hotel de una forma diferente a las actuales. Para ello se ha empleado el modelo del ciclo de vida en cascada, con las fases de análisis, diseño, construcción y pruebas del sistema desarrollado. El software final sigue una arquitectura de tipo cliente/servidor y ha sido realizado con Java como lenguaje base de programación, haciendo uso de algunas librerías como Apache HTTP Request para las conexiones con el servidor remoto como las propias de Android, que facilitan la creación de interfaces gráficas y la gestión de los recursos de los dispositivos en el desarrollo de aplicaciones móviles.