Psalterium Moguntinum

Kirjaston vanhimman painetun teoksen pergamenttilehtiä on löytynyt voutien tilikirjojen kansista. Tämä keskiaikainen lehti on suojannut uusiokäytössä Viipurin

Relation of allium vegetables intake with head and neck cancers : evidence from the INHANCE consortium

SCOPE: Only a few studies analyzed the role of allium vegetables with reference to head and neck cancers (HNC), with mixed results. We investigated the potential favorable role of garlic and onion within the International Head and Neck Cancer Epidemiology (INHANCE) Consortium. METHODS AND RESULTS: We analyzed pooled individual-level data from eight case-control studies, including 4590 cases and 7082 controls. We estimated odds ratios (ORs) and 95% confidence intervals (CIs) for associations between garlic and onion intakes and HNC risk. Compared with no or low garlic use, the ORs of HNC were 0.95 (95% CI 0.71-1.27) for intermediate and 0.74 (95% CI 0.55-0.99) for high garlic use (p for trend = 0.02). The ORs of HNC for increasing categories of onion intake were 0.91 (95% CI 0.68-1.21) for >1 to ≤3 portions per week, and 0.83 (95% CI 0.60-1.13) for >3 portions per week (p for trend = 0.02), as compared to <1 portion per week. We found an inverse association between high onion intake and laryngeal cancer risk (OR = 0.69; 95% CI 0.54-0.88), but no significant association for other subsites. CONCLUSIONS: The results of this pooled-analysis support a possible moderate inverse association between garlic and onion intake and HNC risk. This article is protected by copyright. All rights reserved.

Cardiovascular dysfunction in children conceived by assisted reproductive technologies.

Epidemiological studies demonstrate a relationship between pathological events during foetal development and future cardiovascular risk and the term 'foetal programming of cardiovascular disease' has been coined to describe this phenomenon. The use of assisted reproductive technologies (ARTs) is growing exponentially and 2-5% of children are now born by this procedure. Emerging evidence indicates that ART represents a novel important example of foetal programming. Assisted reproductive technology may modify the cardiovascular phenotype in two ways: (i) ART involves manipulation of the early embryo which is exquisitely sensitive to environmental insults. In line with this concern, ART alters vascular and cardiac function in children and studies in mice show that ART alters the cardiovascular phenotype by epigenetic alterations related to suboptimal culture conditions. (ii) Assisted reproductive technology markedly increases the risk of foetal insults that augment cardiovascular risk in naturally conceived individuals and are expected to have similar consequences in the ART population. Given the young age of the ART population, it will take another 20-30 years before data on cardiovascular endpoints will be available. What is clear already, however, is that ART emerges as an important cardiovascular risk factor. This insight requires us to revise notions on ART's long-term safety and to engage on a debate on its future. There is an urgent need to better understand the mechanisms underpinning ART-induced alteration of the cardiovascular phenotype, improve the procedure and its long-term safety, and, while awaiting this aim, not to abandon medicine's fundamental principle of doing no harm (to future children) and use ART parsimoniously.

El desarrollo psicomotriz en el medio acuático. Aportaciones desde la fenomenología

Esta comunicación presenta la síntesis de una más amplia investigación que tiene como objetivo comprender el potencial pedagógico del espacio acuático sobre los niños y las niñas en edades tempranas. Concretamente centra su mirada sobre el desarrollo psicomotriz del bebé quien en el agua puede experimentar y sentir una gran cantidad de nuevas sensaciones. En este sentido, la comunicación parte de una concepción del agua como un espacio pluridimensional y totalmente diferente del medio habitual de desarrollo humano que es el medio terrestre. Para hacerlo se parte de un planteamiento metodológico de carácter filosófico que utiliza la fenomenología como vía de descubierta y en donde el proceso vivenciado de los investigadores se manifiesta como un elemento decisivo. La finalidad de este enfoque se sustenta en la necesidad de preguntarse sobre el sentido que tienen y que se pueden conferir a las actividades propuestas en el medio acuático.

Usos formales y no formales de las TIC entre los estudiantes universitarios

La presente comunicación muestra los resultados de una investigación que tiene por finalidad identificar y comprender los usos de las TIC por parte de estudiantes universitarios en sus procesos de aprendizaje, con la intención de extraer conclusiones que permitan mejorar el diseño de las situaciones de aprendizaje en contextos formales, haciéndolas más próximas, adaptadas y motivadoras para éstos, teniendo en cuenta los diferentes perfiles de estudiantes identificados y aprovechando la identificación y uso que estos muestran por determinados recursos tecnológicos.

O emprego da termogravimetria para determinar a energia de ativação do processo de combustão de óleos combustíveis

Activation energy (Ea) is a parameter that can be applied to make predictions about the quality of oils to be used in an ICO engine. In this study, Ea was determined by thermogravimetry following two different procedures: ASTM E 1641 and Model-free kinetics. The energies were calculated in the low temperature oxidation (LTO) region for three Brazilian fuel oils (denominated A, B and C) and the results were equal using both methods: 43 kJ mol-1 (alpha=0.1 to 0.9) for oil A, 48 kJ mol-1 (alpha=0.1 to 0.5) and 65 kJ mol-1 (alpha=0.5 to 0.9) for oil B, and 58 kJ mol-1 (alpha=0.1 to 0.5) and 65 kJ mol-1 (alpha=0.5 to 0.9) for oil C. It was concluded that, among the oils studied, sample A was potentially the best option concerning the behavior in the LTO region.

De virorum organis genemtioni inferrientibus, de clysteribus et de usu siphoris in anatomia

Regner de Graaf (1641-1673) oli hollantilainen lääkäri ja anatomian tutkija, joka ensimmäisten joukossa selvitti mikroskoopin avulla ihmisen lisääntymisen fysiologiaa sekä haiman toimintaa. De virorum –teoksessa Graaf julkaisee mm. kiveksen rakennetta koskevan tutkimuksensa. Hän selvitti kiveksen koostuvan tiehyistä, joista hän paikansi siemennesteen kulkeutumistien. Graaf on jäänyt lääketieteen historiaan myös naisen munasarjojen toiminnan uraauurtavana tutkijana.

De existimatione

Invocatio: Divina adfulgente gratia.

Theses miscellaneae

Invocatio: D.D.

L'Univers

1871/12/13 (Numéro 1641).

L'Univers

1871/10/15 (Numéro 1583).

Het wterste ofte Oosterste deel van de Oster Zee beslooten tegens Ruslandt Lijfflandt, Oost Finlandt, in welcken de twe opperste ofte veerste laetplaetsen sijn van geheele Oosterse nauigatie, te weeten der Narua eñ Wijburch, met de omstandlicheijt der Eijlanden, Clippen, eñ Sweetse Schaerē. Doer Lucas Iansz. Wag.

Janamittakaavat: Spaensche mijlen ; Duitzsche mijlen.

Le Petit journal illustré

1921/04/24 (Numéro 1583).

Le Petit journal illustré

1922/06/04 (Numéro 1641).

L'Écho de Paris

1888/07/22 (Numéro 1583).