Comparação da análise miográfica sonora com a força muscular

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação ultrassonográfica quantitativa e qualitativa do canal do carpo em equinos

Pós-graduação em Medicina Veterinária - FMVZ

Indicadores biomecânicos do risco de quedas em marcha com duplas tarefas e a influência do treinamento de equilíbrio com haste vibratória: diferenças entre idosos caidores e não caidores

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Mesenchymal stem cells modulate release of matrix proteins from tendon surfaces in vitro: a potential beneficial therapeutic effect

Aim: Injury of tendons contained within a synovial environment, such as joint, bursa or tendon sheath, frequently fails to heal and releases matrix proteins into the synovial fluid, driving inflammation. This study investigated the effectiveness of cells to seal tendon surfaces and provoke matrix synthesis as a possible effective injectable therapy. Materials & methods: Equine flexor tendon explants were cultured overnight in suspensions of bone marrow and synovium-derived mesenchymal stems cells and, as controls, two sources of fibroblasts, derived from tendon and skin, which adhered to the explants. Release of the most abundant tendon extracellular matrix proteins into the media was assayed, along with specific matrix proteins synthesis by real-time PCR. Results: Release of extracellular matrix proteins was influenced by the coating cell type. Fibroblasts from skin and tendon appeared less capable of preventing the release of matrix proteins than mesenchymal stems cells. Conclusion: The source of cell is an important consideration for cell therapy.

Interactive effects of mechanical ventilation, inhaled nitric oxide and oxidative stress in acute lung injury

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Diabetic peripheral neuropathy in ankles and feet: muscle strength and plantar pressure

This study aims to evaluate and correlate the vascular, sensory and motor components related to the plantar surface in individuals with diabetic peripheral neuropathy. 68 patients were categorized into two groups: 28 in the neuropathic group and 40 in the control group. In each patient, we assessed: circulation and peripheral perfusion of the lower limbs; somatosensory sensitivity; ankle muscle strength; and pressure on the plantar surface in static, dynamic and gait states. We used the Mann-Whitney test and analysis of variance (ANOVA and MANOVA) for comparison between groups, and performed Pearson and Spearman linear correlations amongst the variables (P < 0.05). The somatosensory sensitivity, peripheral circulation and ankle muscle strength were reduced in the neuropathic group. In full peak plantar pressures, no differences were seen between groups, but differences did appear when the foot surface was divided into regions (forefoot, midfoot and hindfoot). In the static condition, the plantar surface area was greater in the neuropathic group. In the dynamic state, peak pressures in the neuropathic group, were higher in the forefoot and lower in the hindfoot, as well as lower in the hindfoot during gait. There were positive or negative correlations between the sensitivity deficit, dorsal ankle flexor strength, plantar surface area, and peak pressure by plantar region. The sensitivity deficit contributed to the increased plantar surface area.

Avaliação da migração das células progenitoras após terapia da tendinite equina

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Soil and biomass mercury emissions during a prescribed fire in the Amazonian rain forest

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Evaluation of mesenchymal stem cell migration after equine tendonitis therapy

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Uso de células-tronco para o tratamento de tendinite em eqüinos

Brazil has the fourth largest horse herd in the world, this is due the recognition and appreciation that the different equestrian games are having within the country. Injuries of the tendon, especially in the digital flexor tendon, are the main cause of athletic life reduction among horses. The treatment of tendinitis in horses seeks full recovery of the damage tissue reestablishing the function previously lost, however conventional treatments have proven to be ineffective when considered the quality of the scar tissue and the rate of recurrence. Due to this, the use of adult stem cells to the treatment of musculoskeletal injuries of horses has been studied for some time. This method of treatment consists of aspiration of bone marrow or removal of subcutaneous fat tissue and implantation of these cells in the injured tissue. After obtaining the bone marrow the implantation can be performed with total bone marrow, with the mononuclear fraction of MSC or with cells cultured in vitro. From the fat tissue is used the stromal vascular fraction obtained by collagenase digestion, followed or not by cell culture. According to some studies, cell therapy with material obtained from bone marrow or adipose tissue has shown to be viable, given that these materials are abundant in repair components such as mesenchymal stem cells (MSC), growth factors and other components of the collagen matrix. Several studies using both types of cells have shown great potential and promising clinical results. However, knowledge of the biology and characterization of these cells remain largely unknown, and therefore is needed great care and caution when using stem cells for the treatment of musculoskeletal disorders in horses

Efeitos de uma partida sobre o pico de torque funcional e convencional nos músculos isquiotibiais e quadríceps de jogadores de futebol de salão com e sem desequilíbrio muscular

Introdução – Uma das causas mais prováveis de lesões esportivas está relacionada aos desequilíbrios musculares e a fadiga muscular, que é evidenciada no decorrer de um jogo de futebol, principalmente no final do jogo. Esta pode ser avaliada através da comparação da força de contração máxima antes e após o exercício. A fadiga produzida durante o jogo diminui a força muscular concêntrica e excêntrica de flexores e extensores do joelho podendo aumentar a incidência de lesões. Objetivo - Avaliar o efeito de uma partida sobre o pico de torque funcional e convencional nos músculos isquiotibiais e quadríceps de jogadores de futebol de salão com e sem desequilíbrio muscular. Método – Oito jogadores de futebol de salão do gênero masculino, com idade entre 18 e 24 anos, fizeram três visitas ao laboratório: 1ª foram realizadas a antropometria e adaptação aos equipamentos; 2ª teste máximo no dinamômetro isocinético para determinar a razão do pico de torque funcional e convencional nos músculos isquiotibiais e quadríceps; 3ª idem ao 2ª, após a partida de futebol de salão. Análise estatística – através das médias ± DP dos dados obtidos foi utilizado o teste t para amostras dependentes e o Mann Whitney para comparação do pico de torque antes e após a partida de futebol de salão e para comparação da relação flexor/extensor pré e pós- esforço, respectivamente. Em ambos os testes foram adotado um nível de significância de p < 0,05. Resultados - Não foram encontradas diferenças significantes entre os grupos de atletas com desequilíbrio muscular na perna dominante (GD) e grupo equilíbrio (GE) e para os extensores e flexores do GD e GE nas condições Con60. Através do Mann Whitney foram encontradas diferenças...(Resumo completo, clicar acesso eletrônico abaixo)

Utilização da ultrassonografia transcuneal como auxílio no diagnóstico da síndrome do navicular em eqüinos

The equine locomotors system alterations are very frequent and corresponds a large portion of cases in equine medicine. The most equine veterinarian’s challenge is to do a precise diagnosis of lameness cause to perform a specific and proper treatment as early as possible. The navicular syndrome is considered responsible for one third of lameness causes and, although much studied, its etiology is still not fully understood. The most varied methods of diagnosis, such as x-ray, magnetic resonance, bursography, scintigraphy, computed tomography and ultrasound, have been used to assess podotrochlear apparatus situation in order to diagnose this syndrome. Among them transcuneal ultrasound can be used to observe some important structures such as the flexor surface of distal sesamoid bone, distal deep digital flexor tendon, distal sesamoid ligament entheses odd and the distal phalanx. The aim of this present paper is provide a brief review on the use and the technique of ultrasonography on third phalanx transcuneal region evaluation and its interpretation on navicular syndrome diagnosis in horses

Importância do casqueamento e ferrageamento no cavalo atleta

The trimming and shoeing are of great significance in the performance and longevity of the athlete horse, and if not done or done incorrectly, cause a variety of limb injuries, which may make unusable the animal for sport, a fact of frequent occurrence, due to the small number of trained professionals in this area. The anatomy of the hoof and its functions should be maintained by maintaining the balance of the same (correct hoof trimming) and, if necessary, proper shoeing, all to avoid the hull balance alterations that lead to osteoarthritis, musculoskeletal disorders, chronic pain at the bead, synovitis, pedal osteitis, navicular disease, in addition to increase tension in the flexor tendons, suspensory ligament and proximal sesamoid causing tendinitis, desmitis and sesamoiditis proximal

Equilíbrio muscular e pico de torque após jogo de futsal

Indoor soccer is a modality of sport similar to football, which is accompanying an increasing of the number of participants. With the growth of this sport, increased as well the number of injuries, which has been requiring greater attention and care from the health professionals. AIMS: To investigate the functional balance before and after an indoor soccer game and analyze the maximum force before and after the game, in order to verify if there is a great loss of muscle strength of knee flexors and extensors during the game. METHODS: The study included seven amateur soccer players. The isokinetic evaluation was made using the Biodex 3 isokinetic dynamometer at velocities of 60°/s and 180°/s with five repetitions at each velocity for each leg. Further, the study analyzed the peak torque of each leg at each speed of the extensor muscles and flexor concentric and eccentric. RESULTS: Compared to the peak torque before and after the game, there were no significant differences. At 60°/s in the non-dominant leg, peak torque decreased after the game of the extensor concentric and eccentric. In the dominant leg there was a decrease of peak torque in eccentric flexion at 60°/s and concentric flexion to 180°/s. Comparing the peak torque between dominance, there was any significant differences in speed. However, in eccentric flexion at 60°/s before the match there was a significant difference. The peak torque of the dominant leg showed better results than the non-dominant leg. Regarding the functional balance there was no statistically significant differences between the muscles involved. CONCLUSION: From the results achieved, it is possible to conclude that the peak torque of flexor eccentric decreases depending on the length of the exercise. This muscle is stronger in the dominant leg, comparing to the non-dominant leg