Isolation of multiple sequences from the Plasmodium falciparum genome that encode conserved domains homologous to those in erythrocyte-binding proteins.

Open reading frames in the Plasmodium falciparum genome encode domains homologous to the adhesive domains of the P. falciparum EBA-175 erythrocyte-binding protein (eba-175 gene product) and those of the Plasmodium vivax and Plasmodium knowlesi Duffy antigen-binding proteins. These domains are referred to as Duffy binding-like (DBL), after the receptor that determines P. vivax invasion of Duffy blood group-positive human erythrocytes. Using oligonucleotide primers derived from short regions of conserved sequence, we have developed a reverse transcription-PCR method that amplifies sequences encoding the DBL domains of expressed genes. Products of these reverse transcription-PCR amplifications include sequences of single-copy genes (including eba-175) and variably transcribed genes that cross-hybridize to multiple regions of the genome. Restriction patterns of the multicopy genes show a high degree of polymorphism among different parasite lines, whereas single-copy genes are generally conserved. Characterization of the single-copy genes has identified a gene (ebl-1) that is related to eba-175 and is likely to be involved in erythrocyte invasion.

Inventory of Silver Plate, Belonging to Harvard College, and in the Keeping of the President, 1886 December 8

Black and white composition book sent to the Harvard College Library containing a typed "copy of notes made in the spring of 1886" by John H. Buck. Includes historical information, and physical descriptions and valuations of the Great Salt, the Stoughton Cup, the Browne Cup, and the christening basin acquired with the donation of Oliver Wendell, as well as notes on other gifts of silver.

III. Research materials used in William C. Lane's article, "Early Silver Belonging to Harvard College," [1923]

This folder contains transcriptions of archival materials used in Lane's research for the article, published by the Colonial Society of Massachusetts in 1923. Included are two letters from the papers of Harvard President Jared Sparks (1849-1853) regarding the christening basin and the role of the College steward in the care of the silver collection; and a 1781 inventory (see also in folder 7) and 1829 Corporation vote excerpted from College records. There are also two notes containing citations.

Access to environmental information in an Open European Society - Directive 2003/4. Research Paper in Law 5/2003

[From the Introduction]. Information gives knowledge and knowledge gives power. Though in all EC Member States, the task to protect the environment is given to the administration, it is obvious that the administration is not the owner of the environment. The environment is everybody's. It is for this reason that administrative decisions which affect the environment must be transparent, open and must strike a balance between the general interest to preserve, protect and improve the quality of the environment on the one hand, the satisfying of specific private or public interests on the other hand. In order to allow at least a certain control of whether the administration strikes the right balance between the need to protect the environment and other legitimate or less legitimate needs, it appears normal and self-evident that information on the environment which is in the hands of public authorities, be also made available to the public and to citizens.

The UN General Assembly Resolution on Access to Legal Aid in Criminal Proceedings - an Example for Europe. IES Policy Brief Issue 2013/04 • May 2013

Summary. The EU’s attempts to adopt an EU-wide instrument on the right to access to legal aid in criminal proceedings have not been successful so far. The important issue was originally part of Measure C of the Roadmap for criminal procedural rights,1 but due to political difficulties legal aid was dropped from the agenda. However, on a different plane agreement was reached on this topic as the United Nations General Assembly (UNGA) has adopted the world’s first international instrument dedicated to access to legal aid in December 2012.2 This policy brief argues that the EU should carry on in the ‘spirit’ of these recent developments and adopt a directive providing suspects and defendants with access to legal aid. 1 Council Resolution of 30 November 2009 on a Roadmap for strengthening procedural rights of suspected or accused persons in criminal proceedings, OJ C 295/1, 4 December 2009; hereafter will be referred to this Council Resolution as the ‘Roadmap’; for further information see M. Jimeno-Bulnes, ‘The EU Roadmap for Strengthening Procedural Rights of Suspected or Accused Persons in Criminal Proceedings’, 4 EUCrim (2009), 157-161. 2 United Nations Principles and Guidelines on Access to Legal Aid in Criminal Justice Systems, A/Res/67/187, 20 December 2012; from here on will be referred to this as the ‘Resolution’.

The story of the diamond necklace, told in detail for the first time, by the aid of contemporary memoires, original letters, and official and other documents; and comprising a sketch of the life of the Countess de la Motte, pretended confidant of Marie-Antoinette, with particulars of the careers of the other actors in the remarkable drama.

"Authorities referred to in this work": p.ix-xii.

Define and limit the jurisdiction of courts sitting in equity ... : report [to accompany H. R. 5315].

Submitted by Mr. La Guardia. Referred to the House calendar and ordered printed March 2, 1932.

Message from the President of the United States communicating in answer to a Senate resolution of December 6, 1877 information in relation to the operation of the Union Pacific Railroad and its branches.

Signed: Charles Devens, Attorney-General.

Administration of the office of the alien property custodian. Message from the President of the United States transmitting in response to Senate resolution no. 299, a copy of the report made by the comptroller general to the President of the United States relative to his investigation of the administration of the office of the alien property custodian.

Read; referred to the Committee on the judiciary and ordered printed, December 22, 1926.

Investigation of driver reactions to tread separation scenarios in the National Advanced Driving Simulator (NADS).

Decreasing vehicle understeer was strongly associated with the likelihood of control loss following both the unexpected and expected tire failures. Knowledge of the imminent tread separation reduced the overall probability of control loss from 55% to 20% and had a significant effect on how quickly drivers responded as well as on the nature of their initial responses (i.e., steering orbraking). Driver age was marginally associated with increased likelihood of vehicle control loss, but only on unexpected trials. Vehicle speed at the time of first steering input also contributed to the probability of control loss. Neither the location of the tire that failed (left rear vs. right rear) nor the specific instructions about how best to respond to the tread separation influenced the probability of control loss. Differences associated with vehicle understeer conditions observed in the present study were large and consistent, independent of driver expectations and across driver age groups. It is thus fair to conclude that in the event of a complete rear-tire detread, the increased difficulty in vehicle handling and the associated increased likelihood of loss of vehicle control with decreasing vehicle understeer generalize to real-world driving.

Report of the eighth International dairy congress, 1928. Message from the President of United States transmitting, pursuant to Public resolution no. 10, Seventieth Congress, approved February 25, 1928, the original report of the eighth International dairy congress, held in Great Britain during June and July, 1928 ...

R. W. Dunlap, chairman.

An encyclopædia of plants; comprising the description, specific character, culture, history, application in the arts, and every other desirable particular respecting all the plants indigenous, cultivated in, or introduced to Britain, combining all the advantages of a Linnean and Jussieuean species plantarum, an historia plantarum, a grammar of botany, and a dictionary of botany and vegetable culture. The whole in English; with the synonymes of the commoner plants in the different European and other languages ...

"Names of books referred to": p. [vii]-xiii.

Ohio River Basin comprehensive survey-- [microform] main report and development program formulation. Communication from the Chairman, United States Water Resources Council, transmitting the Council's report on a comprehensive program for water and related land use in the Ohio River Basin, pursuant to Public law 89-80.

Reuse of record except for individual research requires license from Congressional Information Service, Inc.

Municipal aggregation in Illinois : an estimate of the potential costs and savings from municipal aggregation for selected Illinois communities : a report to the Illinois General Assembly /

"This report addresses the potential benefits of municipal aggregation of retail electric customers as a means for customers to benefit from the Electric Service Customer Choice and Rate Relief Law of 1997 (Public Act 90-561), referred to in this report as the Customer Choice Law. This report was authorized by the General Assembly on June 26, 2002, in Public Act 92-0585."--P. ii.

The history of France, from the earliest period : comprehending every interesting and remarkable occurrence in the annals of that monarchy to its abolition in September 1792 /

Signatures: 6 engr. leaves + A⁴ B-E¹⁸ F¹² G².