The office of motor carriers 5-year research and technology plan.

Mode of access: Internet.

Draughon's practical speller and dictionary : for use in commercial colleges and high schools /

Mode of access: Internet.

National Voluntary Laboratory Accreditation Program : commercial products testing /

"July 1995."

Technology transfer and commercialization : technology transfer report, 1994 /

Mode of access: Internet.

Hindustani self-taught. With English phonetic pronunciation. Containing alphabet and pronunciation - vocabularies - idiomatic phrases & dialogues - travel talk - military, legal, religious, commercial, shooting, fishing terms - Indian titles, castes, servants - money, weights, measures.

Mode of access: Internet.

Practical grammar : a text book for use in public schools and in English departments of business colleges and in commercial departments of academies and high schools /

Mode of access: Internet.

Specifications and test methods for numeric accuracy in programming language standards /

Item 247.

Interim performance criteria for solar heating and cooling systems in commercial buildings /

"NBSIR 76-1562."

Class list of current serial digests and indexes of the literature of science, technology and commerce.

Mode of access: Internet.

Hossfeld's new practical method for learning the Dutch language,

Mode of access: Internet.

Hai kuan yü yen pi hsü = An Anglo-Chinese glossary for customs and commercial use.

Mode of access: Internet.

Studies in language, literature and criticism.

Each number has a distinctive title.

Common command language for file manipulation and network job execution : an example /

Includes bibliographical references (p. 27).

A funny thing happened on the way to the forum: Electronic discussion and foreign language learning

Amongst the opportunities for cross-cultural contact created by the burgeoning use of the Internet are those provided by electronic discussion lists. This study looks at what happens when language students venture out of the classroom (virtual or otherwise) to participate in on-line discussion groups with native speakers. Responses to messages and commentary by moderators and other participants on the (in) appropriateness of contributions allow us to determine what constitutes successful participation and to make suggestions regarding effective teaching strategies for this medium. A case study examines the threads started by four anglophone students of French when they post messages to a forum on the Web site of the French newspaper Le Monde. Investigation of these examples points to the ways in which electronic discussion inflects and is inflected by cultural and generic expectations. We suggest that successful participation on Internet fora depends on awareness of such cultural and generic mores and an ability to work within and/or with them. Teachers therefore need to find ways in which students can be sensitized to such issues so that their participation in such electronic discussion is no longer seen as linguistic training, but as engagement with a cultural practice.

Physical enhancement of transdermal drug application: is delivery technology keeping up with pharmaceutical development?

Advances in molecular biology have given us a wide range of protein and peptide-based drugs that are unsuitable for oral delivery because of their high degree of first-pass metabolism. Though parenteral delivery is the obvious answer, for the successful development of commercial chronic and self-administration usage formulations it is not the ideal choice. Transdermal delivery is emerging as the biggest application target for these agents, however, the skin is extremely efficient at keeping out such large molecular weight compounds and therapeutic levels are never going to be realistically achieved by passive absorption. Physical enhancement mechanisms including: iontophoresis, electroporation, ultrasound, photomechanical waves, microneedles and jet-propelled particles are emerging as solutions to this topical delivery dilemma. Adding proteins and peptides to the list of other large molecular weight drugs with insufficient passive transdermal fluxes to be therapeutically useful, we have a collection of pharmacological agents waiting for efficient delivery methods to be introduced. This article reviews the current state of physical transdermal delivery technology, assesses the pros and cons of each technique and summarises the evidence-base of their drug delivery capabilities.