Characterization of a Leishmania tropica antigen that detects immune responses in Desert Storm viscerotropic leishmaniasis patients.

A chronic debilitating parasitic infection, viscerotropic leishmaniasis (VTL), has been described in Operation Desert Storm veterans. Diagnosis of this disease, caused by Leishmania tropica, has been difficult due to low or absent specific immune responses in traditional assays. We report the cloning and characterization of two genomic fragments encoding portions of a single 210-kDa L. tropica protein useful for the diagnosis of VTL in U.S. military personnel. The recombinant proteins encoded by these fragments, recombinant (r) Lt-1 and rLt-2, contain a 33-amino acid repeat that reacts with sera from Desert Storm VTL patients and with sera from L. tropica-infected patients with cutaneous leishmaniasis. Antibody reactivities to rLt-1 indicated a bias toward IgG2 in VTL patient sera. Peripheral blood mononuclear cells from VTL patients produced interferon gamma, but not interleukin 4 or 10, in response to rLt-1. No cytokine production was observed in response to parasite lysate. The results indicate that specific leishmanial antigens may be used to detect immune responses in VTL patients with chronic infections.

The Effectiveness of Rain Gardens as a Low-Impact Development Strategy for Storm Water Pollution Reduction in Western Washington

Stormwater runoff is a major cause of surface water pollution in western Washington and cost-effective control measures are needed to reduce contamination of receiving waters. This project evaluated the performance efficiency and costs of installing a residential rain garden by inspecting two gardens and testing water quality samples in one. Infiltration through the garden was effective in reducing metals and nutrients as indicated by reductions in copper and nitrate concentrations of 75% and 97%, respectively. The costs were affordable for most homeowners and cost-effective compared to other options. After doing on-site investigations, the storm water manual for the State of Washington was reviewed and eight recommendations were made for improving it.

Evaluating Taphonomic Bias in a Storm-Disturbed Carbonate Platform: Effects of Compositional and Environmental Factors in Lower Jurassic Brachiopod Accumulations (Eastern Subbetic Basin, Spain)

In order to evaluate taxonomic and environmental control on the preservation pattern of brachiopod accumulations, sedimentologic and taphonomic data have been integrated with those inferred from the structure of brachiopod accumulations from the easternmost Lower Jurassic Subbetic deposits in Spain. Two brachiopod communities (Praesphaeroidothyris and Securina communities) were distinguished showing a mainly free-lying way of life in soft-bottom habitats. Three taphofacies are discriminated based on proportion of disarticulation, fragmentation, packing, and shell filling. Taphofacies 1 is represented by thinly fragmented, dispersed brachiopod shells in wackestone beds. Taphofacies 2 is spatially restricted to small lenses where shells are poorly fragmented, rarely disarticulated, usually void filled, and highly packed. Taphofacies 3 is represented by mud or cement filled, loosely packed, articulated brachiopods forming large pocket-like structures. Temporal and spatial averaging were minimally involved in taphofacies 2 and 3. It is interpreted that patchy preservation implies preservation of primary original patchiness of brachiopod communities on the seafloor. The origin of shell-rich taphofacies (2 and 3) is related to rapid burial due to episodic storm activity, while shell-poor taphofacies 1 records background conditions. The nature and comparative diversity of these taphofacies underscores the importance of rapid burial for shell beds preservation. Differences in preservation between taphofacies 2 and 3 are mainly related to environmental criteria, most importantly storm energy and water depth. In contrast, the taxonomic-specific pattern of the communities is a subordinate element of control, controlling only minor within-taphofacies differences in preservation.

Turkey votes: Part I - The storm before the election. EPC Commentary, 26 March 2014

At an election rally on 20 March 2014, Turkish Prime Minister, Recep Tayyip Erdoğan, declared he wanted to “root out Twitter, no matter what the international community thought”. A few hours later Twitter was shut down. The decision backfired. Turkey’s some 12 million Twitter users immediately found ways to circumnavigate the ban; it highlighted the increasingly authoritarian trend of Erdoğan; and it brought immediate condemnation from numerous foreign leaders. The move has been viewed by many Turks as part of an operation to cover up a corruption probe that has consumed Turkey since 17 December, before key local elections on 30 March. The elections, which will be followed by Presidential election in August and political ones expected in 2015, have become a referendum on Erdoğan’s popularity, and are set to shape Turkey’s political landscape. A lot is at stake as a big win for the ruling Justice and Development Party (AKP) may not only be used by Erdoğan to justify his response to the corruption scandal but also risks consolidating his increasingly authoritarian style of governance.

The Political Economy of the 2014-2020 Common Agricultural Policy: An Imperfect Storm. CEPS Paperback, 17 August 2015

After five years of debates, consultations and negotiations, the European institutions reached an agreement in 2013 on the Common Agricultural Policy (CAP) for the 2014-2020 period. The outcome has major implications for the EU’s budget and farmers’ incomes but also for Europe’s environment, its contribution to global climate change and to food security in the EU and in the world. It was decided to spend more than €400 billion during the rest of the decade on the CAP.The official claims are that the new CAP will take better account of society's expectations and lead to far-reaching changes by making subsidies fairer and ‘greener’ and making the CAP more efficient. It is also asserted that the CAP will play a key part in achieving the overall objective of promoting smart, sustainable and inclusive growth. However, there is significant scepticism about these claims and disappointment with the outcome of the decision-making, the first in which the European Parliament was involved under the co-decision procedure. In contrast to earlier reforms where more substantive changes were made to the CAP, the factors that induced the policy discussions in 2008-13 and those that influenced the decision-making did not reinforce each other. On the contrary, they sometimes counteracted one another, yielding an ‘imperfect storm’ as it were, resulting in more status quo and fewer changes. This book discusses the outcome of the decision-making and the factors that influenced the policy choices and decisions. It brings together contributions from leading academics from various disciplines and policy-makers, and key participants in the process from the European Commission and the European Parliament.

Safe Harbour or into the storm? EU-US data transfers after the Schrems judgment. Liberty and security in Europe No. 85/November 2015

In its recent Schrems judgment the Luxembourg Court annulled Commission Decision 2000/520 according to which US data protection rules are sufficient to satisfy EU privacy rules regarding EU-US transfers of personal data, otherwise known as the ‘Safe Harbour’ framework. What does this judgment mean and what are its main implications for EU-US data transfers? In this paper the authors find that this landmark judgment sends a strong message to EU and US policy-makers about the need to ensure clear rules governing data transfers, so that people whose personal data is transferred to third countries have sufficient legal guarantees. Without such rules there is legal uncertainty and mistrust. Any future arrangement for the transatlantic transfer of data will therefore need to be firmly anchored in a framework of protection commensurate to the EU Charter of Fundamental Rights and the EU data protection architecture.

Supporto ad Applicazioni di Web Reputation basate su Piattaforma Apache Storm

Parametro indispensabile di valutazione di un qualsiasi prodotto o servizio, ai giorni nostri, è la web reputation. Sono sempre più numerose le aziende che monitorano la propria "reputazione online". Quest'ultima può esser definita come l'insieme dei messaggi, commenti e feedbacks, positivi, neutri o negativi che siano, di utenti che esprimono la loro opinione tramite il web su un determinato servizio o prodotto rivolto al pubblico. L’applicazione sviluppata, si pone l’obiettivo di analizzare in tempo reale tramite l’utilizzo di Apache Storm, dati provenienti da fonti eterogenee, classificarli tramite KNIME utilizzando tecniche di classificazione quali SVM, alberi decisionali e Naive Bayesian, renderli persistenti mediante l’utilizzo del database NoSQL HBASE e di visualizzarli in tempo reale attraverso dei grafici utilizzando delle servlet, al fine di costituire un valido strumento di supporto per i processi decisionali.

Storm water management model : level I, comparative evaluation of storage-treatment and other management practices /

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