Gene-chip technology and its applications

Gene Chips are finding extensive use in animal and plant science. Generally microarrays are of two kind, cDNA or oligonucleotide. cDNA microarrays were developed at Stanford University, whereas oligonucleotide were developed by Affymetrix. The construction of cDNA or oligonucleotide on a glass slide helps to compare the gene expression level of treated and control samples by labeling mRNA with green (Cy3) and red (Cy5) dyes. The hybridized gene chip emit fluorescence whose intensity and colour can be measured. RNA labeling can be done directly or indirectly. Indirect method involves amino allyle modified dUTP instead of pre-labelled nucleotide. Hybridization of gene chip generally occurs in a minimum volume possible and to ensure the hetroduplex formation, a ten fold more DNA is spotted on slide than in the solutions. A confocal or semi confocal laser technologies coupled with CCD camera are used for image acquisition. For standardization, house keeping genes are used or cDNA are spotted in gene chip that are not present in treated or control samples. Moreover, statistical analysis (image analysis) and cluster analysis softwares have been developed by Stanford University. The gene-chip technology has many applications like expression analysis, gene expression signatures (molecular phenotypes) and promoter regulatory element co-expression.

Analysis of a hyper-diverse seed dispersal network: modularity and underlying mechanisms

Mutualistic interactions involving pollination and ant-plant mutualistic networks typically feature tightly linked species grouped in modules. However, such modularity is infrequent in seed dispersal networks, presumably because research on those networks predominantly includes a single taxonomic animal group (e.g. birds). Herein, for the first time, we examine the pattern of interaction in a network that includes multiple taxonomic groups of seed dispersers, and the mechanisms underlying modularity. We found that the network was nested and modular, with five distinguishable modules. Our examination of the mechanisms underlying such modularity showed that plant and animal trait values were associated with specific modules but phylogenetic effect was limited. Thus, the pattern of interaction in this network is only partially explained by shared evolutionary history. We conclude that the observed modularity emerged by a combination of phylogenetic history and trait convergence of phylogenetically unrelated species, shaped by interactions with particular types of dispersal agents.

The sustainability revolution : A societal paradigm shift - ethos, innovation, government transformation

The Sustainability revolution: A societal paradigm shift – ethos, innovation, governance transformation This paper identifies several key mechanisms that underlie major paradigm shifts. After identifying four such mechanisms, the article focuses on one type of transformation which has a prominent place in the sustainability revolution that the article argues is now taking place. The transformation is piecemeal, incremental, diffuse – in earlier writings referred to as ”organic”. This is a more encompassing notion than grassroots, since the innovation and transformation processes may be launched and developed at multiple levels through diverse mechanisms of discovery and development. Major features of the sustainability revolution are identified and comparisons made to the industrial revolution.

Från traditionellt akademiskt bibliotek till modern lärmiljö : Högskolan Dalarnas bibliotek – förväntningar och resultat

I denna rapport beskrivs idéerna bakom Högskolan Dalarnas prisbelönta bibliotek i Falun. Planerings- och byggprocessen beskrivs och det färdiga resultatet utvärderas, samt de erfarenheter som har gjorts delas.

Fall 2014

Inside this Issue: Archives Kickoff for Winthrop’s Integration CommemorationGiving Thanks … Dean HerringWoodfork ScholarshipActive Friends Member List for 2015Rudy Mancke to SpeakNote From the Chair … Dr. Jane WhiteMembership Form

Summer 2014

Inside this Issue: Bob Gorman RetiresKim Wright to SpeakWhy Friends Matter … Dean HerringActive Member List & Friends Fall ElectionMembership Application

Spring 2014

Inside this Issue: Friends Board Meets Baumgarte to SpeakInaugurations… — Dean HerringA Note From the Sec.- Treas. — Dr. FaulknerMember Application

Fall 2013

Inside this Issue: Friends Board Meets Gorman on Blue SoxGiving Thanks — Dean HerringA Note From the Chair — Dr. WeaverMember Application

Summer 2013

Inside this Issue: Bela and M.H. Herlong Book Talk Success of April 8Welcome New WU President ComstockMergers, Mayhem and More — Dean HerringA Note From the Chair — Dr. WeaverMember Application

Spring 2013

Inside this Issue: Library Endowment Fund EstablishedActive/Life Member List for FriendsA Note From the ChairMembership Form

Fall 2012

Inside this Issue: Business Report of the Friends / Endowment to be EstablishedDean HerringKay McSpadden Wins Norman Mailer AwardA Note From the ChairMember Application

Summer 2012

Inside this Issue: Changes in Friends BylawsDean HerringRenovations UpdateA Note From the ChairMember Application

Spring 2012

Inside this Issue: Current MembershipList State Heritage HorseLibrary Boards to Merge - Dean HerringMajor RenovationsA Note From the ChairMember Application

Fall 2011

Inside this Issue: Sharyn McCrumb 11/3A Few Words from Dean HerringA Note from the ChairFriends of Dacus Library Membership Application

Summer 2011

Inside this Issue: Sharyn McCrumb 11/3Business Meeting Items, 10/7/2011 Dorothy M. MedlinMap and Parking for Events of Oct. 7 and Nov. 3 Membership FormA Note from the Chair