Maisteri Kalevi Kilpi 4/10 1957

Kirje 4.10.1957

A tumor-specific cellular environment at the brain invasion border of adamantinomatous craniopharyngiomas.

Craniopharyngiomas (CP) are benign epithelial tumors of the sellar region and can be clinicopathologically distinguished into adamantinomatous (adaCP) and papillary (papCP) variants. Both subtypes are classified according to the World Health Organization grade I, but their irregular digitate brain infiltration makes any complete surgical resection difficult to obtain. Herein, we characterized the cellular interface between the tumor and the surrounding brain tissue in 48 CP (41 adaCP and seven papCP) compared to non-neuroepithelial tumors, i.e., 12 cavernous hemangiomas, 10 meningiomas, and 14 metastases using antibodies directed against glial fibrillary acid protein (GFAP), vimentin, nestin, microtubule-associated protein 2 (MAP2) splice variants, and tenascin-C. We identified a specific cell population characterized by the coexpression of nestin, MAP2, and GFAP within the invasion niche of the adamantinomatous subtype. This was especially prominent along the finger-like protrusions. A similar population of presumably astroglial precursors was not visible in other lesions under study, which characterize them as distinct histopathological feature of adaCP. Furthermore, the outer tumor cell layer of adaCP showed a distinct expression of MAP2, a novel finding helpful in the differential diagnosis of epithelial tumors in the sellar region. Our data support the hypothesis that adaCP, unlike other non-neuroepithelial tumors of the central nervous system, create a tumor-specific cellular environment at the tumor-brain junction. Whether this facilitates the characteristic infiltrative growth pattern or is the consequence of an activated Wnt signaling pathway, detectable in 90% of these tumors, will need further consideration.

Audit Report on Indian Hills Community College in Ottumwa, Iowa for the year ended June 30, 2006

Audit report on Indian Hills Community College in Ottumwa, Iowa for the year ended June 30, 2006.

Suurlähettiläs Leo Tuominen 1/11 1957

Kirje

Valtiopäivät 1957 (avajaispuhe)

Puhe

Os Sino-moçambicanos da Beira. Mestiçagens Várias

Entre 1858 – data da chegada à Ilha de Moçambique dos primeiros «coolies»2 – e 1975 – data da Independência de Moçambique –, os imigrantes chineses e seus descendentes locais passaram a estar presentes nas relações que se foram tecendo entre os diferentes grupos étnicos e raciais de cada uma das regiões da colónia onde se instalaram, locais de encontro de culturas e de processos complexos de aculturação. Mas nesses encontros e desencontros, as diferenças de cor e de cultura foram quase sempre vividas por preconceitos raciais e étnicos, com frequência expressos nas próprias leis coloniais. Apesar disto, as diferenças foram também matizadas por um multiculturalismo vivido, sem a celebração, contudo, de uma sociedade multicolor. No caso particular da Beira, a sociedade local foi efectivamente caracterizada por um desenvolvimento separado das culturas3 sob o domínio da Companhia de Moçambique e do Estado português subsequente

Överingenjör K. J. Tolonen 9.11.1957 Väg- och vattenbyggnadsstyrelsen

Kirje

Professori Paavo Kastari 9/8 1957

Kirje

Handbook of American Indian languages. Part 2 / by Franz Boas ; with illustrative sketches by Edward Sapir, Leo J. Frachtenberg, and Waldemar Bogoras

Collection : Bulletin - Smithsonian institution. Bureau of American ethnology ; 40

Professori Jan-Magnus Jansson 24/10 1957

Kirje 24.10.1957