A damage model for seismic retrofitting of structures

Numerous damage models have been developed in order to analyse the seismic behavior. Among the different possibilities existing in the literature, it is very clear that models developed along the lines of Continuum Damage Mechanics are more consistent with the definition of damage like a phenomenon with mechanical consequences as they include explicitly the coupling between damage and mechanical behavior. On the other hand, for seismic processes, phenomena such as low cycle fatigue may have a pronounced effect on the overall behavior of the frames and, therefore, its consideration turns out to be very important. However, many of existing models evaluate the damage only as a function of the maximum amplitude of cyclic deformation without considering the number of cycles. In this paper, a generalization of the simplified model proposed by Flórez is made in order to include the low cycle fatigue. Such model employs in its formulation irreversible thermodynamics and internal state variable theory.

Computational model for local damage assesment of structures

In the last years many studies have been developed to analyze the seismic behavior throug the damage concept. In fact, the evaluation of the structural damage is important in order to quantify the safety of new and existing structures and, also, to establish a framework for seismic retrofitting decision making of structures. Most proposed models are based on a post-earthquake evaluation in such a way they uncouple the computation of the structural response from that of damage. However, there are other models which include explicity the existing coupling between the degradation and the structural mechanical beaviour. Those models are closer to the physical reality and its formulation is based on the principles of Continuum Damage Mechanics. In the present work, a coupled model is formulated using a simplified application of the Continuum Damage Mechanics to the analysis of frames and allows its representation in standard finite element programs. This work is part of the activities developed by the Structural Mechanics Department (UPM) within ICONS (European Research Project on Innovative Seismic Design Concepts for New and Existing Structures).

Efficient spatio-temporal hole filling strategy for Kinect depth maps

In this paper we present an efficient hole filling strategy that improves the quality of the depth maps obtained with the Microsoft Kinect device. The proposed approach is based on a joint-bilateral filtering framework that includes spatial and temporal information. The missing depth values are obtained applying iteratively a joint-bilateral filter to their neighbor pixels. The filter weights are selected considering three different factors: visual data, depth information and a temporal-consistency map. Video and depth data are combined to improve depth map quality in presence of edges and homogeneous regions. Finally, the temporal-consistency map is generated in order to track the reliability of the depth measurements near the hole regions. The obtained depth values are included iteratively in the filtering process of the successive frames and the accuracy of the hole regions depth values increases while new samples are acquired and filtered

Performance of buildings with masonry infill walls during the 2011 Lorca earthquake

On Wednesday 11th May 2011 at 6:47 pm (local time) a magnitude 5.1 Mw earthquake occurred 6 km northeast of Lorca with a depth of around 5 km. As a consequence of the shallow depth and the small epicentral distance, important damage was produced in several masonry constructions and even led to the collapse of one of them. Pieces of the facades of several buildings fell down onto the sidewalk, being one of the reasons for the killing of a total of 9 people. The objective of this paper is to describe and analyze the failure patterns observed in reinforced concrete frame buildings with masonry infill walls ranging from 3 to 8 floors in height. Structural as well as non-structural masonry walls suffered important damage that led to redistributions of forces causing in some cases the failure of columns. The importance of the interaction between the structural frames and the infill panels is analyzed by means of non-linear Finite Element Models. The resulting load levels are compared with the member capacities and the changes of the mechanical properties during the seismic event are described and discussed. In the light of the results obtained the observed failure patterns are explained. Some comments are stated concerning the adequacy of the numerical models that are usually used during the design phase for the seismic analysis.

Redes de información y conocimiento climatológico en el mundo hispánico del siglo XVIII

Durante la Ilustración, el imperio español alcanzó su máxima amplitud y las instituciones oficiales incrementaron su apoyo a las ciencias. Para defender sus fronteras y ejercer con eficacia el poder político, económico y religioso, la Corona y la Iglesia necesitaban obtener información precisa --incluida la climatológica-- de las posesiones españolas y de los pobladores de éstas. Fueron varios los procedimientos empleados para ello: sistema de cuestionarios y relaciones geográficas, estudios medico-topográficos, visitas e inspecciones oficiales, expediciones político-científicas, correspondencia epistolar, artículos periodísticos, etc. Dichos procedimientos fueron aplicados por redes de informadores cuyas actuaciones se basaban en la división del trabajo, el reparto de colaboradores en diferentes lugares, el uso de códigos de comunicación comprensibles, el envío de los resultados a los superiores jerárquicos y la toma de decisiones por las autoridades competentes. Las redes de información estaban sometidas a dictámenes que normalizaban su creación y continuidad temporal, daban forma a su estructura interna, especificaban sus cometidos y obligaban a cumplir protocolos y plazos. En su seno se idearon planes de investigación integrados en el estudio general de la Tierra, el ser humano y la cultura. El beneficio de las actuaciones de sus miembros se plasmó en cubrir grandes ámbitos geográficos con el consiguiente ahorro de tiempo, esfuerzos y medios. En sus correspondientes contextos, los miembros de las redes efectuaron estudios climatológicos conforme a intereses, imposiciones y circunstancias específicas. Así, los médicos se interesaron por las condiciones climáticas que influían en la salud humana; los funcionarios reales y los ingenieros militares describieron los climas locales y regionales aptos para el fomento y el control político, jurídico y educativo de los habitantes de los territorios hispánicos; los expedicionarios estudiaron las interacciones entre los fenómenos naturales y las influencias de los accidentes geográficos en los climas; los clérigos se interesaron por los aspectos estéticos, apologéticos y contemplativos de los climas; finalmente, en la prensa de la época se publicaron registros meteorológicos periódicos y trabajos climatológicos varios. En definitiva, el saber climatológico en el mundo hispánico ilustrado aportó algunos rasgos esenciales a la climatología en una etapa pre-fundacional de esta disciplina. Dichos rasgos se desarrollaron generalmente en una escala local o regional y se refirieron a los siguientes asuntos: el calor como principal agente de las modificaciones atmosféricas, de la formación de vapor acuoso y de las precipitaciones; la influencia del suelo en el aumento de humedad y calor en el aire; el poder de los vientos para trasladar de un lugar a otro el frío o el calor, el vapor de agua, los fenómenos atmosféricos y los agentes responsables de las enfermedades contagiosas; las propiedades del aire atmosférico y su capacidad para interaccionar con el medio ambiente; la condición estática y repetitiva de los climas, si bien se admitió que dichos fenómenos podían sufrir modificaciones; la corroboración experimental de las diferencias climáticas entre las zonas tropicales y medias del planeta; la refutación de que la naturaleza americana y sus habitantes eran inferiores a los europeos; y la demostración de que los principios rectores de los fenómenos físicos del Viejo y el Nuevo Mundo eran idénticos. Desde el último tercio del siglo XVIII, los documentos producidos por los componentes de las redes de información incluyeron datos meteorológicos. Pero no siempre se emplearon los mismos instrumentos de medida ni se siguieron los mismos protocolos de indagación en idénticas condiciones. Además, y salvo excepciones, los períodos durante los cuales se recabaron datos atmosféricos fueron relativamente cortos, y los expertos no efectuaron las mismas operaciones aritméticas con los parámetros. Por esta razón, y por la orientación utilitaria de los ilustrados hispánicos, el saber climatológico no obtuvo en el período y en el ámbito geográfico considerados resultados teóricos apreciables; en cambio, dio lugar a una gran cantidad de actividades prácticas con aplicaciones a la medicina, la agricultura, la náutica, el fomento, la prevención de riesgos naturales, etc. La principal utilidad de este trabajo consiste en servir de complemento a los procedimientos actualmente en uso en historia de la hidrología y en climatología histórica. ABSTRACT During the Enlightenment, the Spanish Empire achieved its highest length and State institutions increased their support to sciences. In order to defend their frontiers and to exercise political, economical and religious power, the Crown and the Church needed exact information --including the climatologic one-- about its possessions and its habitants. Some of the procedures employed to get that objective were: system of questionnaires and geographic relations, medical-topographic studies, official visits and inspections, political-scientific expeditions, direct mail, journalistic articles, etc. Those procedures were applied by informers´ networks which obtained, manned and transmitted every kind of data about the natural and moral reality of the Hispanic territories; their actions were based on the division of tasks, the distribution of collaborators at several places, the use of understandable communication codes and the sending of results to the hierarchical superiors; after, the competent authorities took decisions. The information networks were subjected to rules witch regulated its creation, temporary continuity, interior structure, objectives, protocols and periods. Their memberships invented plans about the general research of the Earth, the human beings and the culture; and they contributed to get benefits because of covering large geographic frames and economizing time, effort and means. According to their specifics contexts, concerns, impositions and circumstances, the informers performed climatologic tasks. Thus, the physicians were interested in the climatic conditions which affected to human health; the royal officers and military engineers described the most propitious climates to patronage and political, lawful and educative control of inhabitants of Hispanic territories; the participants in politic-scientific expeditions studied the interactions among natural phenomena and the influence of geographic aspects on the climate; the clergymen underlined the esthetic, apologetic and contemplative face of climates; finally, in the newspapers were published a lot of meteorological data and climatologic works. So, the climatologic knowledge in the Hispanic enlightened world added these essential aspects --referred in a local and regional area-- during the pre-foundational epoch of the climatology: the heat as first agent of atmospheric modifications, aqueous vapor and precipitations; the influx of the land in the increment of humidity and heat of the air; the power of the winds to convey the cold, the heat, the aqueous vapor, the atmospheric phenomena and the agents which caused contagious maladies; the properties of the air and its faculty to mediate with the environs; the static and repetitive condition of the climate and its possibility to experience change; the experimental confirmation of climatic varieties between tropical and central areas of the planet; the negation of the inferiority of the American nature and inhabitants; the demonstration about the equality of the rules which conducted physical phenomena in the Old and the New world. Since the last third part of the eighteenth century, the documents produced by the members of the networks included meteorological data. But the informers were not used to employ the same measure instruments and homogeneous protocols completion in the same conditions. Exceptions besides, the times of taking atmospheric data, usually were very short; and the experts did not carry out the same arithmetical operations with parameters. Because of this reason and the utilitarian guidance of the informers, during the Hispanic Enlightenment, it was not possible to obtain theoretic conclusions about climatologic knowledge; but there were a lot of practical activities applied to Medicine, Agriculture, Navigation, patronage, prevention of natural risks, etc. The main utility of this work consist in favoring the present procedures of the History of Hydrology and Historic Climatology.

Análisis del comportamiento de uniones metálicas viga-soporte mediante modelo de elementos finitos y comparación de resultados con el modelo de nudos y barras

Para el proyecto y cálculo de estructuras metálicas, fundamentalmente pórticos y celosías de cubierta, la herramienta más comúnmente utilizada son los programas informáticos de nudos y barras. En estos programas se define la geometría y sección de las barras, cuyas características mecánicas son perfectamente conocidas, y sobre las cuales obtenemos unos resultados de cálculo concretos en cuanto a estados tensionales y de deformación. Sin embargo el otro componente del modelo, los nudos, presenta mucha mayor complejidad a la hora de establecer sus propiedades mecánicas, fundamentalmente su rigidez al giro, así como de obtener unos resultados de estados tensionales y de deformación en los mismos. Esta “ignorancia” sobre el comportamiento real de los nudos, se salva generalmente asimilando a los nudos del modelo la condición de rígidos o articulados. Si bien los programas de cálculo ofrecen la posibilidad de introducir nudos con una rigidez intermedia (nudos semirrígidos), la rigidez de cada nudo dependerá de la geometría real de la unión, lo cual, dada la gran variedad de geometrías de uniones que en cualquier proyecto se nos presentan, hace prácticamente inviable introducir los coeficientes correspondientes a cada nudo en los modelos de nudos y barras. Tanto el Eurocódigo como el CTE, establecen que cada unión tendrá asociada una curva momento-rotación característica, que deberá ser determinada por los proyectistas mediante herramientas de cálculo o procedimientos experimentales. No obstante, este es un planteamiento difícil de llevar a cabo para cada proyecto. La consecuencia de esto es, que en la práctica, se realizan extensas comprobaciones y justificaciones de cálculo para las barras de las estructuras, dejando en manos de la práctica común la solución y puesta en obra de las uniones, quedando sin justificar ni comprobar la seguridad y el comportamiento real de estas. Otro aspecto que conlleva la falta de caracterización de las uniones, es que desconocemos como afecta el comportamiento real de éstas en los estados tensionales y de deformación de las barras que acometen a ellas, dudas que con frecuencia nos asaltan, no sólo en la fase de proyecto, sino también a la hora de resolver los problemas de ejecución que inevitablemente se nos presentan en el desarrollo de las obras. El cálculo mediante el método de los elementos finitos, es una herramienta que nos permite introducir la geometría real de perfiles y uniones, y nos permite por tanto abordar el comportamiento real de las uniones, y que está condicionado por su geometría. Por ejemplo, un caso típico es el de la unión de una viga a una placa o a un soporte soldando sólo el alma. Es habitual asimilar esta unión a una articulación. Sin embargo, el modelo por elementos finitos nos ofrece su comportamiento real, que es intermedio entre articulado y empotrado, ya que se transmite un momento y el giro es menor que el del apoyo simple. No obstante, la aplicación del modelo de elementos finitos, introduciendo la geometría de todos los elementos estructurales de un entramado metálico, tampoco resulta en general viable desde un punto de vista práctico, dado que requiere invertir mucho tiempo en comparación con el aumento de precisión que obtenemos respecto a los programas de nudos y barras, mucho más rápidos en la fase de modelización de la estructura. En esta tesis se ha abordado, mediante la modelización por elementos finitos, la resolución de una serie de casos tipo representativos de las uniones más comúnmente ejecutadas en obras de edificación, como son las uniones viga-pilar, estableciendo el comportamiento de estas uniones en función de las variables que comúnmente se presentan, y que son: •Ejecución de uniones viga-pilar soldando solo por el alma (unión por el alma), o bien soldando la viga al pilar por todo su perímetro (unión total). •Disposición o no de rigidizadores en los pilares •Uso de pilares de sección 2UPN en cajón o de tipo HEB, que son los tipos de soporte utilizados en casi el 100% de los casos en edificación. Para establecer la influencia de estas variables en el comportamiento de las uniones, y su repercusión en las vigas, se ha realizado un análisis comparativo entre las variables de resultado de los casos estudiados:•Estados tensionales en vigas y uniones. •Momentos en extremo de vigas •Giros totales y relativos en nudos. •Flechas. Otro de los aspectos que nos permite analizar la casuística planteada, es la valoración, desde un punto de vista de costos de ejecución, de la realización de uniones por todo el perímetro frente a las uniones por el alma, o de la disposición o no de rigidizadores en las uniones por todo el perímetro. Los resultados a este respecto, son estrictamente desde un punto de vista económico, sin perjuicio de que la seguridad o las preferencias de los proyectistas aconsejen una solución determinada. Finalmente, un tercer aspecto que nos ha permitido abordar el estudio planteado, es la comparación de resultados que se obtienen por el método de los elementos finitos, más próximos a la realidad, ya que se tiene en cuenta los giros relativos en las uniones, frente a los resultados obtenidos con programas de nudos y barras. De esta forma, podemos seguir usando el modelo de nudos y barras, más versátil y rápido, pero conociendo cuáles son sus limitaciones, y en qué aspectos y en qué medida, debemos ponderar sus resultados. En el último apartado de la tesis se apuntan una serie de temas sobre los que sería interesante profundizar en posteriores estudios, mediante modelos de elementos finitos, con el objeto de conocer mejor el comportamiento de las uniones estructurales metálicas, en aspectos que no se pueden abordar con los programas de nudos y barras. For the project and calculation of steel structures, mainly building frames and cover lattices, the tool more commonly used are the node and bars model computer programs. In these programs we define the geometry and section of the bars, whose mechanical characteristics are perfectly known, and from which we obtain the all calculation results of stresses and displacements. Nevertheless, the other component of the model, the nodes, are much more difficulty for establishing their mechanical properties, mainly the rotation fixity coefficients, as well as the stresses and displacements. This "ignorance" about the real performance of the nodes, is commonly saved by assimilating to them the condition of fixed or articulated. Though the calculation programs offer the possibility to introducing nodes with an intermediate fixity (half-fixed nodes), the fixity of every node will depend on the real connection’s geometry, which, given the great variety of connections geometries that in a project exist, makes practically unviable to introduce the coefficients corresponding to every node in the models of nodes and bars. Both Eurocode and the CTE, establish that every connection will have a typical moment-rotation associated curve, which will have to be determined for the designers by calculation tools or experimental procedures. Nevertheless, this one is an exposition difficult to carry out for each project. The consequence of this, is that in the practice, in projects are extensive checking and calculation reports about the bars of the structures, trusting in hands of the common practice the solution and execution of the connections, resulting without justification and verification their safety and their real behaviour. Another aspect that carries the lack of the connections characterization, is that we don´t know how affects the connections real behaviour in the stresses and displacements of the bars that attack them, doubts that often assault us, not only in the project phase, but also at the moment of solving the execution problems that inevitably happen in the development of the construction works. The calculation by finite element model is a tool that allows us to introduce the real profiles and connections geometry, and allows us to know about the real behaviour of the connections, which is determined by their geometry. Typical example is a beam-plate or beam-support connection welding only by the web. It is usual to assimilate this connection to an articulation or simple support. Nevertheless, the finite element model determines its real performance, which is between articulated and fixed, since a moment is transmitted and the relative rotation is less than the articulation’s rotation. Nevertheless, the application of the finite element model, introducing the geometry of all the structural elements of a metallic structure, does not also turn out to be viable from a practical point of view, provided that it needs to invest a lot of time in comparison with the precision increase that we obtain opposite the node and bars programs, which are much more faster in the structure modelling phase. In this thesis it has been approached, by finite element modelling, the resolution of a representative type cases of the connections commonly used in works of building, since are the beam-support connections, establishing the performance of these connections depending on the variables that commonly are present, which are: •Execution of beam-support connections welding only the web, or welding the beam to the support for the whole perimeter. •Disposition of stiffeners in the supports •Use 2UPN in box section or HEB section, which are the support types used in almost 100% building cases. To establish the influence of these variables in the connections performance, and the repercussion in the beams, a comparative analyse has been made with the resulting variables of the studied cases: •Stresses states in beams and connections. •Bending moments in beam ends. •Total and relative rotations in nodes. •Deflections in beams. Another aspect that the study allows us to analyze, is the valuation, from a costs point of view, of the execution of connections for the whole perimeter opposite to the web connections, or the execution of stiffeners. The results of this analyse, are strictly from an economic point of view, without prejudice that the safety or the preferences of the designers advise a certain solution. Finally, the third aspect that the study has allowed us to approach, is the comparison of the results that are obtained by the finite element model, nearer to the real behaviour, since the relative rotations in the connections are known, opposite to the results obtained with nodes and bars programs. So that, we can use the nodes and bars models, more versatile and quick, but knowing which are its limitations, and in which aspects and measures, we must weight the results. In the last part of the tesis, are relationated some of the topics on which it would be interesting to approach in later studies, with finite elements models, in order to know better the behaviour of the structural steel connections, in aspects that cannot be approached by the nodes and bars programs.

Background foreground segmentation with RGB-D Kinect data: An efficient combination of classifiers

Low cost RGB-D cameras such as the Microsoft’s Kinect or the Asus’s Xtion Pro are completely changing the computer vision world, as they are being successfully used in several applications and research areas. Depth data are particularly attractive and suitable for applications based on moving objects detection through foreground/background segmentation approaches; the RGB-D applications proposed in literature employ, in general, state of the art foreground/background segmentation techniques based on the depth information without taking into account the color information. The novel approach that we propose is based on a combination of classifiers that allows improving background subtraction accuracy with respect to state of the art algorithms by jointly considering color and depth data. In particular, the combination of classifiers is based on a weighted average that allows to adaptively modifying the support of each classifier in the ensemble by considering foreground detections in the previous frames and the depth and color edges. In this way, it is possible to reduce false detections due to critical issues that can not be tackled by the individual classifiers such as: shadows and illumination changes, color and depth camouflage, moved background objects and noisy depth measurements. Moreover, we propose, for the best of the author’s knowledge, the first publicly available RGB-D benchmark dataset with hand-labeled ground truth of several challenging scenarios to test background/foreground segmentation algorithms.

Virtual reconstruction of the 400 toneladas nao from Diego García de Palacio’s Instrucción náutica (1587)

The period between 1570-1620 has left a remarkable amount of documents related to shipbuilding in the Iberian Peninsula. Among them, the Instrucción nautica written by Diego García de Palacio in 1587 is widely recognized as the first published book that includes an extensive discussion of ship design and construction. García de Palacio centres his discussion on a 400 toneladas nao, a series of woodcuts that illustrate the shape and dimensions of the ship accompany the explanation. In the late XVI century ship hulls were designed following procedures based upon an old shipwrightry tradition born in the Mediterranean. By simple rules the master shipwright plots the central frame and tail frames and complete the hull body using wooden ribbands. Computer software for 3D modelling using NURBs surfaces helps to recreate ships hulls. In this work the 400 toneladas nao is reconstructed and her hydrostatic parameters are compared with other ships.

Faye Tull Carter

Faye Tull Carter obtained a Bachelor’s of Science Degree in Home Economics from Lincoln University in 1938. She also received a graduate degree from Teacher’s College, Columbia University in New York. After graduation, Carter accepted the position as Library Assistant at Lincoln University Laboratory School. Upon receiving a Master’s degree in Library Science (MLS) from Case Western Reserve University in Cleveland, Ohio, Carter was appointed the Librarian at Lincoln University Laboratory High School. She was later transferred to the University library, Inman E. Page Library, where she remained until her retirement in 1989. During her years of service, Carter was promoted to the level of Assistant Professor. She taught courses in Library Science and Children’s Literature. Carter’s duties at Inman E. Page Library included creating displays, arranging picture collections and organizing the research material for teachers and students in the Education Department. She also established the Children and Young Adult Literature Collection.

The non-coding RNAs as riboregulators

The non-coding RNAs database (http://biobases.ibch.poznan.pl/ncRNA/) contains currently available data on RNAs, which do not have long open reading frames and act as riboregulators. Non-coding RNAs are involved in the specific recognition of cellular nucleic acid targets through complementary base pairing to control cell growth and differentiation. Some of them are connected with several well known developmental and neuro­behavioral disorders. We have divided them into four groups. This paper is a short introduction to the database and presents its latest, updated edition.

DNA repeats identify novel virulence genes in Haemophilus influenzae.

The whole genome sequence (1.83 Mbp) of Haemophilus influenzae strain Rd was searched to identify tandem oligonucleotide repeat sequences. Loss or gain of one or more nucleotide repeats through a recombination-independent slippage mechanism is known to mediate phase variation of surface molecules of pathogenic bacteria, including H. influenzae. This facilitates evasion of host defenses and adaptation to the varying microenvironments of the host. We reasoned that iterative nucleotides could identify novel genes relevant to microbe-host interactions. Our search of the Rd genome sequence identified 9 novel loci with multiple (range 6-36, mean 22) tandem tetranucleotide repeats. All were found to be located within putative open reading frames and included homologues of hemoglobin-binding proteins of Neisseria, a glycosyltransferase (IgtC gene product) of Neisseria, and an adhesin of Yersinia. These tetranucleotide repeat sequences were also shown to be present in two other epidemiologically different H. influenzae type b strains, although the number and distribution of repeats was different. Further characterization of the IgtC gene showed that it was involved in phenotypic switching of a lipopolysaccharide epitope and that this variable expression was associated with changes in the number of tetranucleotide repeats. Mutation of IgtC resulted in attenuated virulence of H. influenzae in an infant rat model of invasive infection. These data indicate the rapidity, economy, and completeness with which whole genome sequences can be used to investigate the biology of pathogenic bacteria.

Gene disruptions using P transposable elements: an integral component of the Drosophila genome project.

Biologists require genetic as well as molecular tools to decipher genomic information and ultimately to understand gene function. The Berkeley Drosophila Genome Project is addressing these needs with a massive gene disruption project that uses individual, genetically engineered P transposable elements to target open reading frames throughout the Drosophila genome. DNA flanking the insertions is sequenced, thereby placing an extensive series of genetic markers on the physical genomic map and associating insertions with specific open reading frames and genes. Insertions from the collection now lie within or near most Drosophila genes, greatly reducing the time required to identify new mutations and analyze gene functions. Information revealed from these studies about P element site specificity is being used to target the remaining open reading frames.

The nucleotide sequence of chromosome I from Saccharomyces cerevisiae.

Chromosome I from the yeast Saccharomyces cerevisiae contains a DNA molecule of approximately 231 kbp and is the smallest naturally occurring functional eukaryotic nuclear chromosome so far characterized. The nucleotide sequence of this chromosome has been determined as part of an international collaboration to sequence the entire yeast genome. The chromosome contains 89 open reading frames and 4 tRNA genes. The central 165 kbp of the chromosome resembles other large sequenced regions of the yeast genome in both its high density and distribution of genes. In contrast, the remaining sequences flanking this DNA that comprise the two ends of the chromosome and make up more than 25% of the DNA molecule have a much lower gene density, are largely not transcribed, contain no genes essential for vegetative growth, and contain several apparent pseudogenes and a 15-kbp redundant sequence. These terminally repetitive regions consist of a telomeric repeat called W', flanked by DNA closely related to the yeast FLO1 gene. The low gene density, presence of pseudogenes, and lack of expression are consistent with the idea that these terminal regions represent the yeast equivalent of heterochromatin. The occurrence of such a high proportion of DNA with so little information suggests that its presence gives this chromosome the critical length required for proper function.

Remaking Movie Making: The Environmental Impacts of the Film Industry in Southern California

The film and television industry is integral to the economics and culture of the Southern California region. It is also a major contributing factor to the environmental problems in the region. Currently the Motion Picture, Television, and Commercial Industries Act of 1984 is the only regulation written specifically for the entertainment industry. This regulation was created with the purpose of streamlining the film permitting process to prevent run-away production, taking production out of state, and encourage growth. A change in this regulation is needed since studios routinely fail to meet environmental standards or work towards improvement during on-location filming. Amendments to this regulation requiring permits to contain environmental conditions would improve environmental conditions and stay true to the original purpose of the act.

Déjà-vu (again): The Lisbon Treaty Referendum in Ireland. IHS Political Science Series No. 133, February 2013

There has been an increasing use of direct democracy in the form of referendums on aspects of European integration. Two such referendums have been held in Ireland in 2008 and 2009 with the outcome changing from a No to a Yes vote. This paper addresses the question of what explains the change in outcome in two referendums on essentially the same document. It will do so by looking at the role of the campaign in providing information and hence reducing uncertainty, the importance of issue frames and the impact of domestic considerations on vote choice. It is suggested that there has not been a change in underlying attitudes but a change in how the Irish electorate weighed the same factors differently at both referendums. In addition, a change in economic conditions at the time of the second referendum also had an effect on how voters decided the second time around.