Minimum Evaporation Model of Dermatological Delivery Systems. Lamellar Liquid Crystal Formulations Containing Brazilian Nut (Bertholletia excelsa HBK) Vegetable Oil and Guarana Glycolic Extract

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Ecotoxicological Evaluation of Poly(epsilon-Caprolactone) Nanocapsules Containing Triazine Herbicides

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Enhancing effect of lysine combined with other compounds on cephamycin C production in Streptomyces clavuligerus

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Acute Toxicity by Water Containing Hexavalent or Trivalent Chromium in Native Brazilian Fish, Piaractus mesopotamicus: Anatomopathological Alterations and Mortality

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Antiplatelet and Antithrombotic Activities of Non-Steroidal Anti-Inflammatory Drugs Containing an N-Acyl Hydrazone Subunit

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Bacterial cellulose as a template for preparation of hydrotalcite-like compounds

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Synthesis, characterization, and thermal behavior of palladium(II) complexes containing 4-iodopyrazole

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Use of Guanidine Compounds in the Treatment of Neglected Tropical Diseases

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Pyrostegia venusta heptane extract containing saturated aliphatic hydrocarbons induces apoptosis on B16F10-Nex2 melanoma cells and displays antitumor activity in vivo

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Structural and optical properties of Er3+ doped SiO2-Al2O3-GeO2 compounds prepared by a simple route

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

C-2, N-dimethylbenzylamine cyclopalladated compounds: evaluation of cytotoxic, mutagenic and antitubercular activities

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Incorporation of Ca, P, and Si on bioactive coatings produced by plasma electrolytic oxidation: The role of electrolyte concentration and treatment duration

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Pharmacological evaluation and preparation of nonsteroidal anti-inflammatory drugs containing an N-Acyl hydrazone subunit

A series of anti-inflammatory derivatives containing an N-acyl hydrazone subunit (4a–e) were synthesized and characterized. Docking studies were performed that suggest that compounds 4a–e bind to cyclooxygenase (COX)-1 and COX-2 isoforms, but with higher affinity for COX-2. The compounds display similar anti-inflammatory activities in vivo, although compound 4c is the most effective compound for inhibiting rat paw edema, with a reduction in the extent of inflammation of 35.9% and 52.8% at 2 and 4 h, respectively. The anti-inflammatory activity of N-acyl hydrazone derivatives was inferior to their respective parent drugs, except for compound 4c after 5 h. Ulcerogenic studies revealed that compounds 4a–e are less gastrotoxic than the respective parent drug. Compounds 4b–e demonstrated mucosal damage comparable to celecoxib. The in vivo analgesic activities of the compounds are higher than the respective parent drug for compounds 4a–b and 4d–e. Compound 4a was more active than dipyrone in reducing acetic-acid-induced abdominal constrictions. Our results indicate that compounds 4a–e are anti-inflammatory and analgesic compounds with reduced gastrotoxicity compared to their respective parent non-steroidal anti-inflammatory drugs.

Durability of mixed mortar lining containing Dregs-Grits

The improper disposal of industrial waste and exploitation of natural resources has resulted in the scarcity of river sand and environmental degradation, such as river erosions and pollution. This study aimed to assess the durability of mixed mortar lining walls and ceilings, containing 0 (default), 10 and 20% of dregs-grits compounds-waste of the pulp industry-in substitution with river sand. This was done with tests that simulated both natural and artificial conditions: Direct solar incidence (testing ultraviolet radiation), attack by spraying solution (salt spray test), natural warming of the walls and ceilings incidence by indirect solar (thermal degradation) and residential fires (thermogravimetric test), in compliance with both national and/or international standards. The grout containing dregs-grits compounds showed similarity to standard (0%) for testing thermal degradability, thermogravimetric and ultraviolet radiation, but shows significantly less durability when exposed to salty environments.

Frequency upconversion properties of Tm3+ doped TeO2-ZnO glasses containing silver nanoparticles

Frequency upconversion (UC) properties of Tm3+ doped TeO2-ZnO glasses containing silver nanoparticles (NPs) were investigated. Infrared-to-visible and infrared-to-infrared UC processes associated to the Tm3+ ions were studied by exciting the samples with a cw 1050 nm ytterbium laser. The luminescence intensity as a function of laser intensity was also measured using a pulsed 1047 nm Nd3+:YVO laser in order to determine the number of photons participating in the UC processes. Enhancement of the UC signals for samples heat-treated during various time intervals is attributed to the growth of the local field in the vicinity of the NPs. PL enhancement by one-order of magnitude was observed in the whole spectrum of the samples heat-treated during 48 h. On the other hand PL quenching was observed for the samples heat-treated more than 48 h. (c) 2011 Elsevier B.V. All rights reserved.