Muco-cutaneous leishmaniasis in the New World: The ultimate subversion.

Infection by the human protozoan parasite Leishmania can lead, depending primarily on the parasite species, to either cutaneous or mucocutaneous lesions, or fatal generalized visceral infection. In the New World, Leishmania (Viannia) species can cause mucocutaneous leishmaniasis (MCL). Clinical MCL involves a strong hyper-inflammatory response and parasitic dissemination (metastasis) from a primary lesion to distant sites, leading to destructive metastatic secondary lesions especially in the nasopharyngal areas. Recently, we reported that metastasizing, but not non-metastatic strains of Leishmania (Viannia) guyanensis, have high burden of a non-segmented dsRNA virus, Leishmania RNA Virus (LRV). Viral dsRNA is sensed by the host Toll-like Receptor 3 (TLR3) thereby inducing a pro-inflammatory response and exacerbating the disease. The presence of LRV in Leishmania opens new perspectives not only in basic understanding of the intimate relation between the parasite and LRV, but also in understanding the importance of the inflammatory response in MCL patients.

The end of old Europe : the causes of the First World War, 1914-1918.

Dividido en tres partes, se repasan en ellas las características de las cinco grandes potencias europeas del momento: los imperios británico, alemán, ruso, austro-húngaro y la república de Francia, así como las figuras de sus gobernantes; en segundo lugar, trata de la expansión por el continente de un frágil sistema de alianzas, y por último, del polvorín político de los Balcanes. Incluye fragmentos de fuentes históricas originales, así como material de aprendizaje activo: ejercicios, preguntas y pruebas.

‘New World and Old Europe: American Screen Images of Britain and France‘

Contrary to the dearly held belief by Britons that among the nations of the world, they are the favourites of the Americans, Holliwood movies show that even today, judging by the accents of "baddies", the English incarnate the arch-enemy. French villains come a close second. Britain and France are the reactionary, corrupt "old Europe" from whom the Americans tried to cut away ever since 1775, and it is actually the Central-East European countries who as "new Europe" enjoy greater popularity as bearers of hope.

The old Roman world: the grandeur and failure of its civilization.

Mode of access: Internet.

Connexion of sacred and profane history : being a review of the principal events in the world, as they bear upon the state of religion, from the close of the Old Testament history, till the establishment of Christianity /

Includes index.

A new and complete history of the Holy Bible as contained in the Old and New Testaments : from the creation of the world to the full establishment of Christianity ; containing a clear and comprehensive account of every remarkable transaction recorded in the sacred scriptures during a period of upward of four thousand years /

Paged continuously.

The rivals of Acadia, an old story of the New world.

Mode of access: Internet.

A cruise on the Constitution; around the world on Old Ironsides, 1844-1847.

Reprinted from "The United service magazine."

A cowboy detective, a true story of twenty-two years with a world-famous detective agency; giving the inside facts of the bloody Cœur d'Alene labor riots, and the many ups and downs of the author throughout the United States, Alaska, British Columbia and old Mexico, also exicting scenes among the moonshiners of Kentucky and Virginia,

Mode of access: Internet.

The seigneurs of old Canada : a chronicle of New world feudalism /

"Bibliographical note": p. 151-152.

The greatest street in the world : the story of Broadway, old and new, from the Bowling Green to Albany /

Includes bibliography and index.

Where half the world is waking up; the old and the new in Japan, China, the Philippines, and India, reported with especial reference to American conditions,

Mode of access: Internet.