Molecular autopsy in sudden cardiac death and its implication for families: discussion of the practical, legal and ethical aspects of the multidisciplinary collaboration.

Sudden cardiac death (SCD) is a major cause of premature death in young adults and children in developed countries. Standard forensic autopsy procedures are often unsuccessful in determining the cause of SCD. Post-mortem genetic testing, also called molecular autopsy, has revealed that a non-negligible number of these deaths are a result of inherited cardiac diseases, including arrhythmic disorders such as congenital long QT syndrome and Brugada syndrome. Due to the heritability of these diseases, the potential implications for living relatives must be taken into consideration. Advanced diagnostic analyses, genetic counselling, and interdisciplinary collaboration should be integral parts of clinical and forensic practice. In this article we present a multidisciplinary collaboration established in Lausanne, with the goal of properly informing families of these pathologies and their implications for surviving family members. In Switzerland, as in many other countries, legal guidelines for genetic testing do not address the use of molecular tools for post-mortem genetic analyses in forensic practice. In this article we present the standard practice guidelines established by our multidisciplinary team.

A satisfaction survey conducted on patients of a medico-legal consultation.

In 2006, a medico-legal consultation service devoted to adult victims of interpersonal violence was set up at the Lausanne University Hospital Centre, Switzerland: the Violence Medical Unit. Patients are received by forensic nurses for support, forensic examination (in order to establish medical report) and community orientation. In 2008, a telephone survey was conducted on patients. The objectives of the survey were to estimate the degree of patients' satisfaction and to document the use of the medical report by six questions. Among the 476 patients admitted to the VMU in 2007, 132 were interviewed. Their overall satisfaction was high with an average mark of 8.7/10. The medical report was used extensively by the interviewed victims (81%) for its primary function - to be produced as evidence. As the consultations are financed by public funds, these results were of interest for advocacy of long-lasting financial support.

Cobertura y desamparo: garantías jurídicas de los españoles en el Perú (1870-1945) = Coverage and helplessness: legal guarantees of the spanish in Peru (1870-1945)

The archives of the Prefecture of the Peruvian Ministry of Foreign Affairs provide a perspective from which to reconstruct the broad range of legal circumstances in which Spanish residents in various regions of the country find themselves immersed (assets of relatives who have died without wills or family in Peru, political conflicts, legal problems -whether criminal or civil as a result of business activities- or the requested intervention ofconsular authorities when decisions considered detrimental to their compatriots are made by prefects and sub-prefects). The legal framework protecting Spanish nationals in Peru is analysed to understand the mechanisms of immigration in the country and the mechanisms that led them to keep their Spanish nationality, even after establishing wide-reaching family and business interests

Information and risk management during the first trimester care for pregnant women: Some reflections about the ethical challenges and the legal framework in Switzerland. [L'information et la gestion des risques dans le suivi de la grossesse lors du 1er trimestre : quelques réflexions sur le défi éthique et le cadre légal en Suisse.]

The progress in prenatal medicine raises complex questions with respect to the physician-patient relationship. The physician needs to reconcile medical aspects, ethical principles as well as judicial norms. Already, during the first trimester, the physician has to put into practice the schedule combining for each individual pregnancy physical, laboratory and other appropriate exams. Physicians are under the obligation to inform in a clear and comprehensive way without creating unnecessary anxiety for their patients. Legal requirements include informed consent, the respect for the patient's right to self-determination, and compliance with the Swiss federal law on genetic testing, especially with its articles on prenatal screening and diagnosis. This article discusses the complexity of obstetrical practice when it comes to delivering adequate information within the scope of ethical and legal requirements in Switzerland. L'évolution de la médecine prénatale soulève des enjeux complexes dans la relation médecin-patient. Il s'agit de concilier à la fois les aspects médicaux, les principes éthiques et les normes juridiques. Dès le premier trimestre de la grossesse le médecin doit poser le cadre du suivi et des examens appropriés pour chaque grossesse. Son devoir est d'informer de manière claire et précise sans inquiéter inutilement, en respectant l'exigence légale d'un consentement éclairé et plus largement le droit de la patiente à l'autodétermination ainsi que le cadre de la loi fédérale suisse sur l'analyse génétique humaine dans le domaine du dépistage et du diagnostic prénatal. Cet article discute de la complexité de l'information et de l'application des principes éthiques et légaux dans la pratique obstétricale en Suisse.

Legal Issues for FOSS-based Supply Chain Management ¿ Black Duck Software

Open source is typically outside of normal commercial software procurement processes.The Challenges.Increasingly diverse and distributed set of development resources.Little/no visibility into the origins of the software.Supply Chain Comparison: Hardware vs Software.Open source has revolutionized the mobile and device landscape, other industries will follow.Supply chain management techniques from hardware are useful for managing software.SPDX A standard format for communicating a software Bill of Materials across the supply chain.Effective management and control requires training, tools, processes and standards.

Legal issues in promoting FOSS in R+D projects - Policy, Organisation and Management

Creating and using FLOSS in R+D projects raises several legal issues, which need to be managed as soon as possible - preferably during the project planning stage. Challenges in the areas of project structure and policy, licenses and licensing, exploitation strategies, community management, and FLOSS-friendliness in general all have their legal aspects, which are commented here. Some recommendations are made for assisting in the use of FLOSS in R+D projects, especially in multiple party consortiums.

Short communication. Mutual pheromone antagonism in two sympatric corn borers, Sesamia nonagrioides and Ostrinia nubilalis, under field conditions

In previous studies, we demonstrated cross-antagonism in pheromone perception between pheromone componentsof the two corn (Zea mays L.) borers Sesamia nonagrioides Lefèbvre (Lepidoptera: Noctuidae) and Ostrinia nubilalis (Hübner) (Lepidoptera: Crambidae) in the laboratory and in the field. The two pheromone components identified as responsible for this cross-antagonism were Z 11-16:Ald, a minor component of S. nonagrioides pheromone, and Z 11-14:Ac, the main component of the pheromone of the Z-strain of O. nubilalis, which inhibited the response of O. nubilalis and S. nonagrioides, respectively. Here, we study this antagonism phenomenon in the field by air permeation of maize plots with each of the two components separately and measurement of mating in caged couples of the two corn borers on treated and untreated plots during three years. A significant reduction in mating rates was observed on the permeated plots: 7% for S. nonagrioides and 12% for O. nubilalis. When dispenser charges (200 ng) were increased by 50% and 75% in the third year, no decrease in mating rates was recorded at either of the increased concentrations. On the other hand, the use of large cages resulted in an increase of 8% to 12% in the percentage of unmated females in each of the two corn borers suggesting that at more realistic field corn borer densities, 0,1 couples/plant instead of the 2 couples/plant used in this experiment, cross-antagonism in the two corn borers could be higher than that recorded in small cages.

La modificació del criteri d'adquisició de la personalitat civil: una anàlisi des del dret civil català

Malgrat que des de feia ja molt de temps existien raons socials, mediques i jurídiques més que suficients, han tingut de passar més de cent vint anys (1889-2011) per a que es dugués a terme la necessària reforma de l’obsolet article 30 CC. mitjançant la qual s’ha prescindit, per fi, de l’estranya, per anòmala, i criticada condicio iuris – figura humana i supervivència independent més enllà de les primeres 24 hores – que caracteritzava l’adquisició de la personalitat civil en el Dret espanyol, sense parangó en els ordenaments del seu entorn jurídic. El nou criteri, fonamentat únicament en el naixement entès des de la seva consideració jurídica – despreniment del claustre matern -, permet prescindir, des d’aquest “moment”, de qualsevol limitació a la projecció jurídica, tant personal com patrimonial, del nounat, incloent per tant els efectes successoris mortis causa. El desencadenant de la novetat legislativa, vehiculada per la nova Llei del Registre Civil (2011), no fou un altre que la regulació dispensada amb anterioritat (2010) per l’article 211-1.1 del Codi civil de Catalunya, que va fer descansar ja en el mer naixement l’atribució de la personalitat civil. Tant la tramitació parlamentària de la modificació de l’art. 30 CC. com el desenvolupament de la qüestió competencial plantejada pel Govern de l’Estat en contra del precepte català, confirmen, en un procés de mútua interferència, la influencia determinant que sobre la reforma duta a terme va tenir la decisió de Catalunya de legislar sobre aquesta matèria.

Els serveis socials en l'administració comarcal : marc legal i institucional

El govern de la Comuniata Autònoma de Catalunya ha reinstituït l'organització comarcal que ja havia implantat la Generalitat durant la II República, Ara però, s'ha otorgat als Consells Comarcals, com a òrgan de govern de les comarques, un marcat caràcter institucional i administratiu. Per tant, l'administració comarcal a Catalunya s'adscriu entre les administracions locals, i com un nou nivell intermedi entre el municipi i la província (mentre aquesta subsisteix) o bé la Comunitat Autònoma. Aquesta modificació del model estatal d'Administracions Públiques, evidentment, condiciona l'organització del sistema de serveis socials.El present treball pretén estudiar, a través del repositoir legislatiu, el marc institucional en el qual s'organitzen els serveis social d'àmbit comarcal. Això ens ha de permetre conèixer més el context pròxim en el què actuen els equips i professionals del medi comarcal. Ells són els principals destinataris d¡aquesta proposta d'anàlisis: però igualment pot ajudar als altres professionals a reflexionar sobre el procés d'estructuració dels serveis de benestar social que s'està desenvolupant a Catalunya

Nuevo marco legal sobre prestaciones económicas: anotaciones críticas a la Ley 13/2006 + despliegue

Las prestaciones económicas son un complemento necesario y, a menudo, un soporte indispensable para los objetivos de inclusión y de autonomía que procura el sistema de Servicios Sociales. El Parlament de Catalunya aprobó hace un año la primera ley que regula específicamente las prestaciones de carácter económico vinculadas al sistema, y que se añade, por tanto, al ordenamiento jurídico de los Servicios Sociales. Este artículo quiere ser una presentación comentada de dicha ley –incluyendo su despliegue hasta la fecha2 – haciendo lo que se podría decir una lectura crítica y desde una perspectiva de Servicios Sociales. El análisis repasa, a grandes rasgos, los aspectos más importantes de la ley, e intenta hacer compatible una exposición pedagógica con una interpretación más personal de búsqueda de significado.