Peritoneal and serum interleukin-18 levels are not increased in women with minimum or mild endometriosis

Interleukin-18 (IL-18) is a cytokine that belongs to the IL-1 family. Endometriosis is strongly associated with sub-fertility, and affects about 15% of women of reproductive age. IL-18 may favor the progression of endometriosis. The objective of the present study was to determine the concentration of IL-18 in the serum and peritoneal fluid of infertile women with endometriosis. Forty infertile and 25 fertile women were screened in a teaching hospital. Thirty-four infertile patients with minimal or mild endometriosis and 22 fertile controls were enrolled in the study. The primary outcome was the estimate of IL-18 levels and the secondary outcome was the correlation between serum and peritoneal levels of IL-18. There were no differences between the two groups regarding age, body mass index and levels of peritoneal fluid IL-18 (mean ± SD): 290.85 ± 173.02 pg/mL for infertile women vs 374.21 ± 330.15 pg/mL for controls; or serum IL-18: 391.07 ± 119.71 pg/mL for infertile women vs 373.42 ± 129.11 pg/mL for controls. However, a positive association was found between serum and peritoneal IL-18 levels in patients with endometriosis: r = 0.794, P = 0.0001. All measurements were carried out at the same time by the Human IL-18 Immuno Assay ELISA kit (MBL Co. Ltd., Japan). The present study did not find evidence supporting the hypothesis that IL-18 levels are associated with infertility in women with minimal and mild endometriosis, although a positive correlation was detected in these women between peritoneal and serum levels of IL-18.

Plan of the Grand Central Hotel

Pre 1913 plan showing the Grand Central Hotel and Santorium Co. Ltd. on St. Paul Street, St. Catharines, Ont.

Humberstone Shoe Company Limited Minute Book

Book contains meeting minutes of the Board of Directors of the Humberstone Shoe Company Ltd., held at the Office of McLeod, Young, Weir and Co. Limited, Metropolitan Building, Toronto. Board of Directors includes: H.H. Knoll (President), J.H. Radcliffe, E. K. Reiner, T.H. Kinnear, L.B. Spencer. There is some correspondence, annual reports, contracts, by-laws, statements of profit and loss etc. throughout the book.

The Death of Brock at Queenston Heights, 1812: Imperial Tobacco Company silk card

General Isaac Brock was a British Army officer and administrator who was promoted to Major General. He was responsible for defending Upper Canada against the United States. He died at the Battle of Queenston Heights during the War of 1812. Bartholome Houde and George E. Tuckett (Tuckett was mayor of Hamilton Ontario in 1896) manufactured and sold tobacco before Confederation. In 1841, the company was called B. Houde and Grothe. When Houde retired in 1822 his son in law, Francis Xavier Dussault took over the company. In 1903, the company was called B. Houde and Company Ltee. and it was run by Dussault’s two sons J.A. Dussault and J.E. Dussault. The B. Houde Company had become part of American Tobacco Ltd. which merged with Empire Tobacco Co. Ltd. to form the Imperial Tobacco Company in 1908 in the St. Henri district of Montreal. In 2008, the company celebrated their centennial. Cigarette silks were either enclosed in packets of cigarettes or were redeemable by mail. People would sew these silks together to create quilts or table covers. Some cigarette packages even included instructions for making these items.

Photographs of secretarial staff at Lightning Fastener, ca. 1935

Lightning Fastener Co. Ltd. was a zipper manufacturer located on Niagara Street in St. Catharines. It was founded by Gideon Sundback, the inventor of the modern fastener. Sundback was born in Sweden, but settled in the United States in 1905. It was here that he designed and patented a “separable fastener” in 1913. Although he lived in Hoboken, New Jersey, he decided to establish a manufacturing facility for his invention in Canada, choosing St. Catharines over other locations such as Fort Erie and Hamilton. At the height of its success, the company employed more than 500 people and produced more than 50 million zippers annually. Over time, the company had difficulty remaining competitive and was forced to close in 1981.

Article - "Navigation emphasized in the Governor-General's Race"

An article written by Dorothy Rungeling for the magazine Canadian Aviation. She writes about her experience during the Governor-General's Race and her win.

Article - "Fixed Wing to Whirly Bird"

An article written by Dorothy Rungeling about her experience flying a helicopter for the first time. She is instructed by Bert Ratliff of the Bell Helicopter Corp. in a Bell G2 Trooper.

Sir Robert Burnett Labels

A collection of Sir Robert Burnett labels. The company was established in England in 1770, but these labels read "Distilled and Bottled according to the Original Formula of Sir Robert Burnett Co., Ltd. London W.I., England by The Sir Robert Burnett Co. A Division of Distillers Corporation Ltd. Montreal, Canada".

Stelco records, 1951-1989

The Steel Company of Canada (Stelco) was formed in 1910 with the incorporation of the Canada Screw Co. Ltd., the Montreal Rolling Mills Co., the Dominion Wire Manufacturing Co. Ltd., the Hamilton Steel and Iron Co. Ltd., and the Canada Bolt and Nut Co. Ltd. By the 1920s, the company was the largest producer of steel ingots in Canada. The 1930s saw continued success and expansion of the company as Stelco increased its iron and steel capacity by 50 percent. The company continued to prosper throughout the next several decades, with sales revenues exceeding one billion dollars in 1974. In 1980, the company officially changed its name to Stelco, in order to simplify its name in both the French and English language. The company began to experience financial difficulties beginning with the recession in 1982. The troubles persisted for the next 25 years as a result of a decreased demand for steel, labour disputes, and high steel imports. In 2004, Stelco entered bankruptcy protection. By 2007, Stelco had lost $240 million in its first four quarters after emerging from bankruptcy protection. That same year Stelco was purchased by the United States Steel Corp. Despite efforts to restructure the company, bankruptcy was again declared in 2014.

Efectos de la reducción del nivel del Lago Chad sobre la Seguridad Regional (Nigeria, Níger, Chad y Camerún) durante el período de 2000-2010

El Lago Chad ha sido durante varias décadas, una fuente de supervivencia económica para millones de personas que habitan en cuatro Estados a saber; Nigeria, Níger, Chad y Camerún. No obstante, el cambio climático, el aumento acelerado de la población, la explotación insostenible y la mala regulación de los Estados ribereños han sido los principales factores que han dado lugar, en la última década, a la dramática reducción del nivel del Lago Chad. Teniendo en cuenta que los Estados aledaños al Lago, se encuentran inmersos en una Interdependencia Compleja, este nuevo contexto, ha tenido un impacto directo en la región, debido a que ha agravado otras variables económicas, sociales, ambientales y políticas, dejando un ambiente de inseguridad regional. De esta manera, la reducción de la Cuenca del Lago Chad representa una amenaza compartida que vincula estrechamente a Nigeria, Níger, Chad y Camerún, lo que permite vislumbrar la existencia de un Subcomplejo de Seguridad Regional.

Análisis de las relaciones bilaterales entre Pakistán y Estados Unidos en materia de seguridad (Periodo 2007 - 2010)

Después de los ataques del 11 de septiembre de 2001, Pakistán se ha convertido en uno de los principales aliados de Estados Unidos para combatir las fuerzas terroristas de Al-Qaeda y los talibán en el centro y sur de Asia. La alianza bilateral no ha manifestado resultados determinantes para aliviar los problemas de seguridad en Pakistán, por el contrario, la yihad islámica se ha fortalecido en su población y los ataques terroristas que atentan contra la población civil y el aparato estatal se vuelven cada vez mas frecuentes, en razón de lo anterior, los grupos insurgentes en Pakistán han fortalecido su capacidad operativa y expandido su escenario de influencia.

La cooperación cultural como herramienta para la reafirmación identitaria en el Grupo Visegrád y sus efectos en el posicionamiento del mismo dentro de la Unión Europea 2004-2012

El Grupo Visegrád es un escenario de cooperación multilateral, conformado por Polonia, República Checa, Eslovaquia y Hungría, el cual tiene como objetivo principal contribuir al cumplimiento de los intereses de dichos países, por medio de la financiación de proyectos culturales. El interés de esta monografía consiste en determinar la incidencia de la cooperación cultural en la reafirmación identitaria de cada uno de los miembros del Grupo y, por ende, en la manera como éstos se proyectan dentro de la Unión Europea. Así pues, se identifican los principales hechos históricos que han moldeado los intereses de los países del V4 y que condujeron a la creación de una estructura institucional sólida, que ha servido como plataforma para el accionar de dichos países dentro del bloque europeo. Se utiliza la perspectiva constructivista de Alexander Wendt, la cual permite entender la naturaleza de la cooperación y, su relación con las identidades y los intereses de los Estados.

Limitaciones y obstáculos de MINUSTAH en materia de cooperación humanitaria y desarrollo en Haití (2000-2014)

Este estudio de caso pretende analizar las limitaciones y obstáculos a los que la misión de estabilización, MINUSTAH, se ha enfrentado en el proceso de reconstrucción de Haití antes, durante y después del terremoto de 2010. Además, busca identificar los elementos que han hecho de MINUSTAH una misión cuyo objetivo inicial de carácter político y estabilización se orientó hacia la asistencia humanitaria a causa de una catástrofe natural tal como el terremoto de 2010. En esta medida y bajo el marco de cooperación internacional para el desarrollo, este estudio de caso avanza por un proceso evaluativo del papel de MINUSTAH en la consolidación del Estado haitiano.