999 resultados para Jewish architecture.
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An die deutschen Muetter! 12000 juedische Soldaten sind fuer das Vaterland auf dem Felde der Ehre gefallen. Christliche und juedische Helden haben gemeinsam gekaempft und ruhen gemeinsam in fremder Erde. 12000 Juden fielen im Kampf! Blindwuetiger Parteihass macht vor den Graebern der Toten nicht halt. Deutsche Frauen, duldet nicht, dass die juedische Muetter in ihrem Schmerz verhoehnt wird. Reichsbund juedischer Frontsoldaten e.V.
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Handwritten on verso: Baden-Baden marsch von du Synagoge zum Central hotel 1938
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Thomas Krakauer's father, Hans Krakauer is second from left in the rear row.
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Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide significance that together explained one-fifth of the heritability for adult height. By testing different numbers of variants in independent studies, we show that the most strongly associated approximately 2,000, approximately 3,700 and approximately 9,500 SNPs explained approximately 21%, approximately 24% and approximately 29% of phenotypic variance. Furthermore, all common variants together captured 60% of heritability. The 697 variants clustered in 423 loci were enriched for genes, pathways and tissue types known to be involved in growth and together implicated genes and pathways not highlighted in earlier efforts, such as signaling by fibroblast growth factors, WNT/beta-catenin and chondroitin sulfate-related genes. We identified several genes and pathways not previously connected with human skeletal growth, including mTOR, osteoglycin and binding of hyaluronic acid. Our results indicate a genetic architecture for human height that is characterized by a very large but finite number (thousands) of causal variants.