378 resultados para Inconsistency
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OBJECTIVETo determine the current status of the literature regarding the clinical efficacy and complication rates of cryoablation vs radiofrequency ablation in the treatment of small renal tumours.METHODSA review of the literature was conducted. There was no language restriction. Studies were obtained from the following sources: MEDLINE, EMBASE and LILACS.Inclusion criteria were (i) case series design with more than one case reported, (ii) use of cryoablation or radiofrequency ablation, (iii) patients with renal cell carcinoma and, (iv) outcome reported as clinical efficacy.When available, we also quantified the complication rates from each included study.Proportional meta-analysis was performed on both outcomes with a random-effects model. The 95% confidential intervals were also calculated.RESULTSThirty-one case series (20 cryoablation, 11 radiofrequency ablation) met all inclusion criteria.The pooled proportion of clinical efficacy was 89% in cryoablation therapy from a total of 457 cases. There was a statistically significant heterogeneity between these studies showing the inconsistency of clinical and methodological aspects.The pooled proportion of clinical efficacy was 90% in radiofrequency ablation therapy from a total of 426 cases. There was no statistically significant heterogeneity between these studies.There was no statistically significant difference regarding complications rate between cryoablation and radiofrequency ablation.CONCLUSIONSThis review shows that both ablation therapies have similar efficacy and complication rates.There is urgency for performing clinical trials with long-term data to establish which intervention is most suitable for the treatment of small renal masses.
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Context - Several paradoxical cases of infliximab-induced or-exacerbated psoriatic lesions have been described in the recent years. There is disagreement regarding the need to discontinue infliximab in order to achieve the resolution of these adverse cutaneous reactions specifically in inflammatory bowel disease (IBD) patients. Objective - To systematically review the literature to collect information on IBD patients that showed this adverse cutaneous reaction, focusing mainly on the therapeutic approach. Methods - A systematic literature review was performed utilizing Medline, Embase, SciELO and Lilacs databases. Published studies were identified, reviewed and the data were extracted. Results - Thirty-four studies (69 IBD patients) met inclusion criteria for review. There was inconsistency in reporting of some clinical and therapeutic aspects. Most patients included had Crohn's disease (89.86%), was female (47.83%), had an average age of 27.11 years, and no reported history of psoriasis (84.05%). The patients developed primarily plaque-type psoriasis (40.58%). There was complete remission of psoriatic lesions in 86.96% of IBD patients, existing differences in the therapeutic approaches; cessation of infliximab therapy led to resolution in 47.83% of cases and 43.48% of patients were able to continue infliximab therapy. Conclusion - As increasing numbers of IBD patients with psoriasis induced or exacerbated by infliximab, physicians should be aware of its clinical manifestations so that appropriate diagnosis and treatment are properly established. The decision whether to continue or discontinue infliximab should be individualized.
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Includes bibliography
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Includes bibliography
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The main purpose of this study was to analyze the modified physical properties of an educational resource for facilitating the handling of a child with dyskinetic cerebral palsy. The participant of the study was a six year old child with dyskinetic cerebral palsy enrolled in a regular early childhood education classroom. The educational resource that was selected was a brick game, in which the physical properties of weight, size and texture had been modified. The analysis was made regarding the quality of upper limb movement to the variables: righting index, scalar displacement (s), average speed (As) and time (t). The results showed that combined large size and heavy weight did not have a satisfactory outcome, affecting both grasping the educational resource and fitting. There was also inconsistency in children with cerebral palsy's responses. There is variation in the results, though a standard cannot be established. Thus, this study contributed to understanding the motor responses of a child with dyskinetic cerebral palsy when participating in a fitting activity with educational resources in which the physical properties had been modified.
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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Pós-graduação em Ginecologia, Obstetrícia e Mastologia - FMB
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O presente trabalho consiste em uma pesquisa qualitativa que se propôs a observar e analisar sob o enfoque psicanalítico, o desenvolvimento emocional de um bebê institucionalizado. Para isso realizou-se um estudo de caso, cujo instrumento metodológico consistiu na adaptação do método Bick de Observação de Bebês. As adaptações versam sobre o ambiente que é institucional, à redução do tempo de observação para o período de quatro meses, ao contexto das supervisões que, devido à escassez de pesquisadores que utilizam este método em Belém, restringiu a maioria das supervisões ao par observador e supervisor, sendo que este último exerceu a função paralela de orientador deste estudo. Realizou-se a pesquisa em um abrigo estadual que acolhe crianças de zero a seis anos, onde vivia Miguel, um bebê que foi abandonado por motivo de dificuldades financeiras justificadas pela mãe. Miguel foi observado desde os seus 20 dias de vida até os quatro meses, através de observações semanais, com duração de uma hora, totalizando 20 observações, as quais foram registradas e submetidas às supervisões. Os resultados foram organizados em três capítulos principais: 1) Sobre o desenvolvimento emocional de bebês que remonta ao campo teórico da psicanálise de crianças 2) Sou visto, logo existo que esboça a relação bebê-observadora, com enfoque nos aspectos transferenciais e contratransferenciais que permearam essa relação 3) Colo bom, colo mau que aborda o ambiente de cuidados vivenciados por Miguel no contexto de acolhimento institucional e 4) O colorido afetivo de Miguel que abrange os aspectos marcantes do desenvolvimento emocional de Miguel no abrigo. Ao final desta jornada, Miguel revelou-se um bebê que durante os primeiros meses experimentou ansiedades catastróficas, que demandavam acolhimento e contenção, usava o choro e o olhar para atrair contato, todavia, raras vezes era atendido por motivos diversos inerentes ao contexto de institucionalização; posteriormente mostrou-se mais familiarizado com o ambiente, utilizando recursos como vocalizações e sorrisos para relacionar-se. Apesar da instabilidade e inconstância dos cuidados, Miguel foi interpretado como símbolo do bebê que vencendo obstáculos e enfrentando um mundo ambivalente em sua máxima expressão, revelou que não existe situação ideal para o desenvolvimento emocional.
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The National Program for Strengthening Family Agriculture (Pronaf) has included family farmers into the scope of public policies, by following the trends of policies from the 1990s to democratize access to financial resources. Sustainability has been put into the program. In this study, the overall purpose was analyze the objectives of Pronaf, in the context of economic development. We found out that Pronaf would not allow evaluating the relation among activities conducted and results obtained by the program. Thus, it would be inconsistent. Besides analyzing official documents, other specific objectives were to analyze the consistency of Pronaf and, in case of inconsistency, propose a logical framework matrix. No project was found, only the legislation. The analyse of the latter does not allow filling the matrix and this indicates an inconsistency. A full matrix was proposed.
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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This paper reports a research to evaluate the potential and the effects of use of annotated Paraconsistent logic in automatic indexing. This logic attempts to deal with contradictions, concerned with studying and developing inconsistency-tolerant systems of logic. This logic, being flexible and containing logical states that go beyond the dichotomies yes and no, permits to advance the hypothesis that the results of indexing could be better than those obtained by traditional methods. Interactions between different disciplines, as information retrieval, automatic indexing, information visualization, and nonclassical logics were considered in this research. From the methodological point of view, an algorithm for treatment of uncertainty and imprecision, developed under the Paraconsistent logic, was used to modify the values of the weights assigned to indexing terms of the text collections. The tests were performed on an information visualization system named Projection Explorer (PEx), created at Institute of Mathematics and Computer Science (ICMC - USP Sao Carlos), with available source code. PEx uses traditional vector space model to represent documents of a collection. The results were evaluated by criteria built in the information visualization system itself, and demonstrated measurable gains in the quality of the displays, confirming the hypothesis that the use of the para-analyser under the conditions of the experiment has the ability to generate more effective clusters of similar documents. This is a point that draws attention, since the constitution of more significant clusters can be used to enhance information indexing and retrieval. It can be argued that the adoption of non-dichotomous (non-exclusive) parameters provides new possibilities to relate similar information.