Efeitos do exercício físico multimodal nas concentrações plasmáticas de biomarcadores, funções cognitivas e funcionalidade em pacientes com doença de Alzheimer

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Processos de leitura em escolares com transtorno do déficit de atenção/hiperatividade

This study aimed to characterize and compare the performance of students with Attention Deficit Hyperactivity Disorder and students with good academic performance on the readingassessment processes. Forty students ranging from 8 years and 2 months old to 10 years and 11 months old, from both genders, from 1st to 4th grades of elementary level, participated inthis study, distributed in two groups: GI, with 20 students with interdisciplinary diagnosis ofAttention Deficit Hyperactivity Disorder (ADHD), and GII, 20 students with good academic performance,paired with GI according to gender, age and school level. The students wereassessedthrough the Brazilian adaptation of the Assessment Process of Reading – PROLEC, composedof four blocks: identification of letters, lexical, syntactic and semantic processes. Statisticallysignificant difference occurred between GI and GII in the PROLEC tests, with the exception of thesame-different and lexical decision tests, indicating that the students from GI presented inferior performance when compared with students from GII. Regarding the classification of the resultsof PROLEC, there was a statistically significant difference in the lexical, syntactic and semanticprocesses and the letter and sound test, with the exception of same-different tests of identificationof letters process. The findings suggests that the group of students with ADHD showsinferior performance compared to the group without disabilities, highlighting that the attentionfactor affects the cognitive functions impairing the acquisition of skills necessary for reading.

Memória, envelhecimento e qualidade de vida: a perspectiva da psicologia cognitiva

The concern with aging has increased in recent decades throughout the world, before the gradual increase in life expectancy of the population. Researchers have been developing a diverse in nature, in order to subsidize the activities of professionals in the field of Gerontology to promote autonomy, preservation of cognitive functions and thus contribute to healthy aging. This article presents a review of the literature on memory and aging from the perspective of cognitive psychology. The bibliography contains studies focusing on different subjects, in this sense. A significant number of works have been undertaken in order to investigate mechanisms and benefits of training on memory in healthy elderly and / or cognitive improvement. A concept that deserves attention in such studies is the study of aspects of meta-memory. However, there are still relatively few controlled studies on the subject.

Triple-aspect monism: Physiological, mental unconscious and conscious aspects of brain activity

Brain activity contains three fundamental aspects: (a) The physiological aspect, covering all kinds of processes that involve matter and/or energy; (b) the mental unconscious aspect, consisting of dynamical patterns (i.e., frequency, amplitude and phase-modulated waves) embodied in neural activity. These patterns are variously operated (transmitted, stored, combined, matched, amplified, erased, etc), forming cognitive and emotional unconscious processes and (c) the mental conscious aspect, consisting of feelings experienced in the first-person perspective and cognitive functions grounded in feelings, as memory formation, selection of the focus of attention, voluntary behavior, aesthetical appraisal and ethical judgment. Triple-aspect monism (TAM) is a philosophical theory that provides a model of the relation of the three aspects. Spatially distributed neuronal dendritic potentials generate amplitude-modulated waveforms transmitted to the extracellular medium and adjacent astrocytes, prompting the formation of large waves in the astrocyte network, which are claimed to both integrate distributed information and instantiate feelings. According to the valence of the feeling, the large wave feeds back on neuronal synapses, modulating (reinforcing or depressing) cognitive and behavioral functions.

Physical Exercise in MCI Elderly Promotes Reduction of Pro-Inflammatory Cytokines and Improvements on Cognition and BDNF Peripheral Levels

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Square stepping exercise: uma revisão

Many studies inform that with aging process there’s a drop, not only in the cognitive functions, but also in the functional fitness. This drop can damage the old people’s daily activities, making them lose their independence. These declines can be softened with the practice of physical exercises. So, the aim of this study is to develop a systematic review in the literature which is the quantity of lectures done using the Square Stepping Exercise, we use a follow keyword “Square Stepping Exercise”. We performed a search in the following databases: PUBMED, Portal de Periódicos CAPES, Google Acadêmico e Catálogo Athena (acervo da Biblioteca de todos os campus da UNESP). Those procedures were complemented for manual searches in the references of the found lectures, like the access to the curriculum vitae, plataforma Lattes. There were analyzed articles, in Portuguese and English. Language were selected 11 studies (2 monografies, 1 masters lecture, 1 experience relatorie, 1 book chapter and 6 articles). The references found had improvement in motor and cognitive aspects. With this review, it was concluded that the SSE showed itself as a useful method to get better and/or maintain the analyzed aspects. It’s also necessary new studies with different populations, tips of analyse, periods of time and other aspects

Efeitos da atividade física sobre equilíbrio, risco de quedas e função cognitiva de idosos com demência de Alzheimer: Salma Stéphany Soleman Hernandez. -

The Alzheimer’s dementia represents a clinical condition inherent to many chronic and neurodegenerative diseases that are usually related to a decline in the cognitive and physical functions. The objective of this experimental design research was to analyze the effects of a regular and systemized physical activity program over the cognitive functions, balance and risk of falls of elderly with Alzheimer’s Dementia (DA). The sample was made of 16 elderly with DA, distributed in two groups: a) intervention group – GI (9 subjects that had participated in a program of physical activity, that consisted of 3 weekly sessions of 60 minutes each, in alternated days and with a duration of 6 months); b) control group – GC (7 subjects that did not participate in the program of physical activity). Both groups maintained the doctoral and pharmacological assistance routine. The subjects passed through two different evaluations (pre and post-intervention) the questionnaire (Mini-exam of Mental State for cognitive functions) and motor tests (Berg Functional Balance Scale – EEFB, Timed Up-and-Go (TUG) time (TUGs) and steps (TUGp) and the test of agility and dynamic balance (AGILEQ) of the American Alliance for Health, Physical Education Recreation and Dance for elderly). The obtained results were, respectively in the pre and post-intervention moments: a) AGILEQ (GI = 39,1 ± 10,2 and 38,4 ± 8,9 and GC = 45,6 ± 16,7 and 59,9 ± 22,0 seconds) with the statistically interaction significant (ANOVA two-way; F1,14 = 32,07; p=0,01) between groups and moments; b) TUGs (GI = 9,8 ± 2,5 and 9,5 ± 3,3 and GC = 10,6 ± 4,5 and 12,7 ± 7,3 seconds) the test UMann Whitney did not appoint any significant differences between the groups in the post-intervention moment, however the analyzes of Wilcoxon evidenced a ...(Complete abstract click electronic access below)

Variabilidade da frequência cardíaca, funções cognitivas e nível de atividade física em pacientes com doença de Alzheimer

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Reação postural de pacientes com doença de Parkinson e idosos sadios no teste de retropulsão instrumentado

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Efeito do nível de atividade física nas concentrações da ADAM 10 em sujeitos com doença de Alzheimer e saudáveis

Pós-graduação em Ciências da Motricidade - IBRC

O sofrimento gera luta: o impacto da anemia falciforme e da vivência do adoecimento no desenvolvimento psíquico de portadores da doença

Pós-graduação em Saúde Coletiva - FMB

Efeitos do extrato de soja (Glycine max) na motricidade, nas funções cognitivas e sintomas do climatério: um estudo duplo cego

Pós-graduação em Ciências da Motricidade - IBRC

Efeitos do treinamento aeróbio no fator de crescimento endotelial vascular (VEGF), funções cognitivas e funcionalidade motora na Doença de Alzheimer

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Square stepping exercise: uma nova atividade física para idosos

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Effects of Methylphenidate on performance of a practical pistol shooting task: a quantitative electroencephalography (qEEG) study

Abstract Background The present study examined absolute alpha power using quantitative electroencephalogram (qEEG) in bilateral temporal and parietal cortices in novice soldiers under the influence of methylphenidate (MPH) during the preparatory aiming period in a practical pistol-shooting task. We anticipated higher bi-hemispheric cortical activation in the preparatory period relative to pre-shot baseline in the methylphenidate group when compared with the control group because methylphenidate has been shown to enhance task-related cognitive functions. Methods Twenty healthy, novice soldiers were equally distributed in control (CG; n = 10) and MPH groups 10 mg (MG; n = 10) using a randomized, double blind design. Subjects performed a pistol-shooting task while electroencephalographic activity was acquired. Results We found main effects for group and practice blocks on behavioral measures, and interactions between group and phases on electroencephalographic measures for the electrodes T3, T4, P3 and P4. Regarding the behavioral measures, the MPH group demonstrated significantly poorer in shooting performance when compared with the control and, in addition, significant increases in the scores over practice blocks were found on both groups. In addition, regarding the electroencephalographic data, we observed a significant increase in alpha power over practice blocks, but alpha power was significantly lower for the MPH group when compared with the placebo group. Moreover, we observed a significant decrease in alpha power in electrodes T4 and P4 during PTM. Conclusion Although we found no correlation between behavioral and EEG data, our findings show that MPH did not prevent the learning of the task in healthy subjects. However, during the practice blocks (PBs) it also did not favor the performance when compared with control group performance. It seems that the CNS effects of MPH demanded an initial readjustment period of integrated operations relative to the sensorimotor system. In other words, MPH seems to provoke a period of initial instability due to a possible modulation in neural activity, which can be explained by lower levels of alpha power (i.e., higher cortical activity). However, after the end of the PB1 a new stabilization was established in neural circuits, due to repetition of the task, resulting higher cortical activity during the task. In conclusion, MPH group performance was not initially superior to that of the control group, but eventually exceeded it, albeit without achieving statistical significance.