Atividade antiedema do pró-fármaco polimérico PDC-70 derivado do diclofenaco

The PDC-70 polymeric prodrug derived from the diclofenac has shown antiedema activity when administered through intramuscular route in rats. Besides that it has produced superior activity when compared to the diclofenac sodium. These promising results indicate antiinflammatory activity for the PDC-70 polymeric prodrug.

Brasil: mortalidad por sexo y grupos de edades, en el período 1950-70

Incluye Bibliografía

High levels of heat shock protein 70 are associated with pro-inflammatory cytokines and may differentiate early- from late-onset preeclampsia

Preeclampsia (PE), a specific syndrome of pregnancy, can be classified into early and late onset, depending on whether clinical manifestations occur before or after 34 weeks' gestation. We determined whether plasma concentrations of Hsp60 and Hsp70 were related to circulating cytokine levels, as well as kidney and liver functions, in early- and late-onset PE. Two hundred and thirty-seven preeclamptic women (95 with early- and 142 with late-onset PE) were evaluated. Plasma levels of Hsp60, Hsp70, and their specific antibodies, tumor necrosis factor-alpha (TNF-α), interleukin (IL)-1, IL-10, IL-12, and soluble TNF-α-receptor I (sTNFRI) concentrations, were determined by enzyme-linked immunosorbent assay (ELISA). Concentrations of Hsp70, TNF-α, IL-1β, IL-12, and sTNFRI were significantly elevated in patients with early-onset PE compared with women with late-onset PE; IL-10 levels were significantly lower in the early-onset PE group. Concentrations of urea, uric acid, proteinuria, glutamic oxaloacetic transaminase (GOT), glutamic pyruvic transaminase (GPT), and lactate dehydrogenase (LDH) were also significantly higher in early-onset PE. The percentage of infants with intrauterine growth restriction was also significantly higher in women with early-onset PE. There were positive correlations between Hsp70 levels and TNF-α, TNFRI, IL-1β, IL-12, GOT, GPT, LDH, and uric acid concentrations in early-onset PE group. Thus, early-onset PE was associated with greater maternal and fetal impairment. There are differences in pathophysiology between early- and late-onset PE, highlighting by the difference in Hsp70 levels. © 2013 Elsevier B.V. All rights reserved.

Biodegradability of PP/PHBV (70/30) blend films

This study aimed to investigate the biodegradation of polypropylene/ poly(hydroxybutyrate-co-hydroxyvalerate) (PP/PHBV) blend (70/30, w/w) films in soil, monitoring the evolution of CO2 using the respirometric method. The polymeric films were incubated at 28°C ± 2°C for 180 days in biometer flasks, and the sequence of biodegradation percentage was PP/PHBV (70/30) > PP, that is, 15% and 0%, respectively. Fourier transform infrared spectroscopy and X-ray diffraction measurements showed that biodegradation occurs in the blend PP/PHBV interphases. Preferentially, the microbial action occurs in the fraction of the biodegradable polymer (PHBV), and it influences the PP fraction morphology, which showed some significant changes in the monomer unit sequences and the organization of the chains. © 2013 Wiley Periodicals, Inc.

Morfo-anatomia de raízes tuberosas de mandioca (Manihot esculenta Crantz) cultivar IAC 576-70 em diferentes preparos do solo

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A revista Artéria: uma amostragem das poéticas intersemióticas dos anos 70 aos 90

Pós-graduação em Artes - IA

Panama: analisis de la participacion de la poblacion en la actividad economica, y de algunas caracteristicas de la poblacion economicamente activa, durante los anos 1960-70

Incluye Bibliografía

A atuação das tendências políticas no movimento estudantil da Universidade de São Paulo (USP) no contexto da ditadura militar dos anos 70

Pós-graduação em Ciências Sociais - FFC

Transferencias no contributivas a personas mayores. Análisis comparativo de dos programas: 70 y más y pensión alimentaria de la Ciudad de México

El trabajo compara dos programas de transferencias no contributivas a personas mayores (PTNCPM) en México: uno local (el Programa de la Pensión Alimentaria del Distrito Federal, creado en 2001) y otro nacional (el Programa 70 y Más, impulsado en 2007). Se documenta el proceso de envejecimiento de la población en los países de la Región Norte de América Latina y el Caribe; se revisan los principales instrumentos internacionales sobre los derechos de las personas mayores, así como los marcos jurídicos de ambos programas; se propone una guía para el análisis de los PTNCPM desde un enfoque de derechos, y se lleva a cabo una comparación sobre la base de diversas variables. Entre los hallazgos principales del trabajo se encontraron modificaciones de los criterios de elegibilidad: el programa nacional dejó de lado la universalidad para iniciar un proceso de focalización en 2012; la cobertura alcanzó el 100% en ambos casos y se redujo a casi 60% en el programa nacional y a 82% en el local; las prestaciones monetarias directas e indirectas en el caso local duplican las del nacional; en éste hay un sesgo de género favorable a los varones, mientras que en aquél es favorable a las mujeres; la sostenibilidad financiera está asegurada por ley sólo en el programa local; el presupuesto asignado como porcentaje del PIB es del doble en el caso local con respecto al nacional; y la capacitación de tomadores de decisiones, cuadros medios y personal operativo es fundamental para el mejoramiento y ampliación de los programas. Se concluye que el enfoque de derechos garantiza la institucionalidad y sostenibilidad de los programas, además de un ingreso mínimo universal que promueve la cohesión social.

Caracterização da transição micélio-levedura em Paracoccidioides brasiliensis e sua relação com a expressão do gene do choque térmico 70(HSP70)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

História e guerrilha: entre a tradição rural e a prática urbana. O Brasil das décadas de 60 e 70 do século XX

Pós-graduação em História - FCHS