937 resultados para 56-435
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Abstract Background. In 2011, Alabama, neither a border state nor hold a significantly large Hispanic population, passed the most restrictive state immigration law, The Beason-Hammon Alabama Taxpayer and Citizen Protection Act, HB 56. This omnibus law was far-reaching in its restrictions, including, but not limited to, identification, public services, employment, housing, and law enforcement. Objectives. This research explores the dominant tropes present in the narrative surrounding the anti-immigration legislative activity in Alabama that created fertile ground for the passage of such a punitive immigration law. Methods. Newspaper articles from 2007 to 2011 in Alabama¿s Birmingham News and Press-Register, the two most circulated newspapers in the state, were attained from NewsLibrary.com, an online database of 5,311 newspapers and other news sources. Results. Seven dominant tropes were identified in the articles that pushed for anti-immigration policies. These tropes claimed (1) the US-Mexico border is not secure, (2) the federal government has failed to enact comprehensive immigration reform, (3) immigrants steal jobs, hurt the economy, and (4) burden public services, (5) immigrants are criminals and terrorists, (6) they refuse to assimilate and learn English, and (7) there has been a dramatic percent change in the Hispanic and illegal populations. These tropes cumulatively worked together to create anti-immigration sentiment that pushed for the passage of HB 56.
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We present a case of a pathologic humerus fracture in a patient with the initial diagnosis of Gaucher's disease, which is the most frequent form of lipidosis transmitted as an autosomal recessive trait. It often results in orthopaedic complications with pain, osteonecrosis, fractures and joint infractions. If there is cause for suspicion, beta-glucocerebrosidase in white blood cells should be measured because of the important consequences for treatment. Therapy with a modified enzyme is effective in managing the disease.
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The use of glasses doped with PbS nanocrystals as intracavity saturable absorbers for passive Q-switching and mode locking of c-cut Nd:Gd0.7Y0.3VO4, Nd:YVO4, and Nd:GdVO4 lasers is investigated. Q-switching yields pulses as short as 35 ns with an average output power of 435 mW at a repetition rate of 6–12 kHz at a pump power of 5–6 W. Mode locking through a combination of PbS nanocrystals and a Kerr lens results in 1.4 ps long pulses with an average output power of 255 mW at a repetition rate of 100 MHz.
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INTRODUCTION: Thyroid cancer is the most common endocrine malignancy. The outcomes of patients with relapsed thyroid cancer treated on early-phase clinical trials have not been systematically analyzed. PATIENTS AND METHODS: We reviewed the records of consecutive patients with metastatic thyroid cancer referred to the Phase I Clinical Trials Program from March 2006 to April 2008. Best response was assessed by Response Evaluation Criteria in Solid Tumors. RESULTS: Fifty-six patients were identified. The median age was 55 yr (range 35-79 yr). Of 49 patients evaluable for response, nine (18.4%) had a partial response, and 16 (32.7%) had stable disease for 6 months or longer. The median progression-free survival was 1.12 yr. With a median follow-up of 15.6 months, the 1-yr survival rate was 81%. In univariate analysis, factors predicting shorter survival were anaplastic histology (P = 0.0002) and albumin levels less than 3.5 g/dl (P = 0.05). Among 26 patients with tumor decreases, none died (median follow-up 1.3 yr), whereas 52% of patients with any tumor increase died by 1 yr (P = 0.0001). The median time to failure in our phase I clinical trials was 11.5 months vs. 4.1 months for the previous treatment (P = 0.04). CONCLUSION: Patients with advanced thyroid cancer treated on phase I clinical trials had high rates of partial response and prolonged stable disease. Time to failure was significantly longer on the first phase I trial compared with the prior conventional treatment. Patients with any tumor decrease had significantly longer survival than those with any tumor increase.
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BACKGROUND New psychoactive substances (NPS) have become increasingly prevalent and are sold in internet shops as 'bath salts' or 'research chemicals' and comprehensive bioanalytical methods are needed for their detection. METHODOLOGY We developed and validated a method using LC and MS/MS to quantify 56 NPS in blood and urine, including amphetamine derivatives, 2C compounds, aminoindanes, cathinones, piperazines, tryptamines, dissociatives and others. Instrumentation included a Synergi Polar-RP column (Phenomenex) and a 3200 QTrap mass spectrometer (AB Sciex). Run time was 20 min. CONCLUSION A novel method is presented for the unambiguous identification and quantification of 56 NPS in blood and urine samples in clinical and forensic cases, e.g., intoxications or driving under the influence of drugs.
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Vorbesitzer: Abraham Merzbacher
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Vorbesitzer: Johann Qwentin von Ortenberg; Jungo Frosch; Bartholomaeusstift Frankfurt am Main
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Vorbesitzer: Ratsbibliothek Frankfurt am Main
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Vorbesitzer: Petrus Scriptoris de Seligenstadt; Dominikanerkloster Frankfurt am Main
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12 Briefe zwischen Anna Weil und Max Horkheimer, 1935-1936; 82 Briefe und Beilage zwischen Felix Weil, Margot de Weil und Max Horkheimer, 1934-1941; 1 Brief von D. Charnass an Felix Weil, 25.04.1936; 4 Briefe zwischen Dolson Wood Company und Max Horkheimer, 16.05.1941, 19.05.1941; 1 Brief von Max Horkheimer an das American Consul General Havana, 21.03.1941; 1 Brief von Max Horkheimer an Byron H. Uhl, 07.01.1941; 2 Brief zwischen Dorothy B. Padwa und Max Horkheimer, 01.03.1940, 05.03.1940; 1 Brief von Max Horkheimer an Collector of Customs, 08.10.1938; 1 Brief von D. Charnass an Felix Weil, 25.04.1936; 2 Briefe zwischen D. Charnass und Charles Rosenheck, 25.04.1936; 1 Zeugnis von The State Education Department an Charles Rosenheck, 25.04.1936; 1 Zeugniskopie, 24.04.1936; 1 Brief von Charles Rosenheck über Felix Weil, 23.04.1936; 1 Bescheinigung von Albert Marinelli, 24.04.1936; 3 Briefe zwischen George Weil und Max Horkheimer, 22.02.1937, 1937; 2 Briefe zwischen Georg Weil und Max Horkheimer, 06.04.1942, 08.04.1942; 1 Brief von Hans Weil an Max Horkheimer, 01.01.1939; 2 Briefe von Max Horkheimer an Duggan; 1 Brief und Beilage von Hans Weil an Paul Tillich, 11.10.1940; 1 Brief von Max Horkheimer an Hilde Frankel, 12.10.1940; 3 Briefe und 1 Beilage Juliana Weil, 06.06.1936, 1936; 1 Brief von Weinbaum an Max Horkheimer; 2 Briefe zwischen Jacob Weinberger und Max Horkheimer, 20.02.1946, 28.02.1946; 2 Briefe zwischen Ria Weinig, Margit Weinig und Max Horkheimer, 20.07.1949, 29.07.1949; 1 Brief und Beilage von B. Weinryb an Max Horkheimer, 04.03.1941; 1 Brief von Philipp Weintraub an Max Horkheimer, 20.11.1937;