An die Herren Urwähler zur ersten Kammer in der 42. bis 45. und 48. Wahlabtheilung: Die Wahl der Wahlmänner für die erste Kammer ist nicht mehr fern ...

Welsch (Projektbearbeiter): Einladung an die Wahlglieder der Berliner Wahlbezirke 42 bis 45 und 48 zur Vorberatung über die Ausübung des Urwählerrechts für die erste Kammer

Trends and characteristics of attendance at the emergency department of a Swiss university hospital: 2002-2012.

BACKGROUND The numbers of people attending emergency departments (EDs) at hospitals are increasing. We aimed to analyse trends in ED attendance at a Swiss university hospital between 2002 and 2012, focussing on age-related differences and hospital admission criteria. METHODS We used hospital administrative data for all patients aged ≥16 years who attended the ED (n=298,306) at this university hospital between 1 January 2002, and 31 December 2012. We descriptively analysed the numbers of ED visits according to the admission year and stratified by age (≥65 vs <65 years). RESULTS People attending the ED were on average 46.6 years old (standard deviation 20 years, maximum range 16‒99 years). The annual number of ED attendances grew by n=6,639 (27.6%) from 24,080 in 2002 to 30,719 in 2012. In the subgroup of patients aged ≥65 the relative increase was 42.3%, which is significantly higher (Pearson's χ2=350.046, df=10; p=0.000) than the relative increase of 23.4% among patients<65 years. The subgroup of patients≥65 years attended the ED more often because of diseases (n=56,307; 85%) than accidents (n=9,844; 14.9%). This subgroup (patients≥65 years) was also more often admitted to hospital (Pearson's χ2=23,377.190; df=1; p=0.000) than patients<65 years. CONCLUSIONS ED attendance of patients≥65 years increased in absolute and relative terms. The study findings suggest that staff of this ED may want to assess the needs of patients≥65 years and, if necessary, adjust the services (e.g., adapted triage scales, adapted geriatric screenings, and adapted hospital admission criteria).

Mutation Update of the CLCN5 Gene Responsible for Dent Disease 1

Dent disease is a rare X-linked tubulopathy characterized by low molecular weight proteinuria, hypercalciuria, nephrocalcinosis and/or nephrolithiasis, progressive renal failure, and variable manifestations of other proximal tubule dysfunctions. It often progresses over a few decades to chronic renal insufficiency, and therefore molecular characterization is important to allow appropriate genetic counseling. Two genetic subtypes have been described to date: Dent disease 1 is caused by mutations of the CLCN5 gene, coding for the chloride/proton exchanger ClC-5; and Dent disease 2 by mutations of the OCRL gene, coding for the inositol polyphosphate 5-phosphatase OCRL-1. Herein, we review previously reported mutations (n = 192) and their associated phenotype in 377 male patients with Dent disease 1 and describe phenotype and novel (n = 42) and recurrent mutations (n = 24) in a large cohort of 117 Dent disease 1 patients belonging to 90 families. The novel missense and in-frame mutations described were mapped onto a three-dimensional homology model of the ClC-5 protein. This analysis suggests that these mutations affect the dimerization process, helix stability, or transport. The phenotype of our cohort patients supports and extends the phenotype that has been reported in smaller studies.

Psalm 42 [Musikdruck]

Hirsch Liwschütz

Mitteilungen aus dem deutschen Bureau der Alliance Israélite Universelle : (Berlin N. 24, Oranienburgerstr. 42/43 I)

Alliance Israélite Universelle / Deutsches Büro

Ms. germ. fol. 42 - Entwurf eines Strafgesetzbuches für den Kanton Zürich. 1. Teil. Von den Verbrechen und deren Bestrafung

Vorbesitzer: Antiquariat Baer

Die zweite Übersetzung des Saadiahnischen Buches "Emunoth wedeoth" angeblich von Berechjah hanakdan : (Munch. Cod. 42. Hebr.)

Philipp Bloch

Die zweite Übersetzung des Saadiahnischen Buches "Emunoth wedeoth" angeblich von Berechjah hanakdan : (Munch. Cod. 42. Hebr.)

Philipp Bloch

Der geschichtliche Inhalt der beiden Psalmen 42 u. 43 und die Zeit ihrer Abfassung

Benzion Behrend

Zu Jeruschalmi Berachoth 6 a, 42 und Abodah Zarah 43 b, 70

Viktor Aptowitzer

John dos Passos: Der 42. Breitegrad ... [Rezension]

N. H.

Ms. Barth. 42 (Ausst. 19) - Guda-Homiliar

Vorbesitzer: Bartholomaeusstift Frankfurt am Main;