Kansanedustajien urheilupoliittiset velvoitteet

Puhe Eduskunnassa 3.11.1965

Exposição dos trabalhadores de enfermagem às cargas de trabalho e suas consequências

RESUMO Objetivo Mensurar a exposição dos trabalhadores às cargas de trabalho, aos processos de desgaste e as suas consequências, por meio de indicadores. Método Estudo epidemiológico descritivo, transversal e quantitativo, realizado em doze unidades de três hospitais de ensino do município de São Paulo. A população foi de 452 trabalhadores de enfermagem e a coleta de dados foi realizada por meio do software Sistema de Monitoramento da Saúde do Trabalhador de Enfermagem (SIMOSTE) nos prontuários dos trabalhadores de enfermagem. Os dados foram analisados segundo indicadores que permitiram apreender a dinâmica organizacional (DO), os problemas de saúde dos trabalhadores (PS) e suas consequências (CO). Resultados Os indicadores PS evidenciam 879 exposições às cargas de trabalho e 1.355 processos de desgaste. Os indicadores de CO mostram 2.709 dias perdidos em um ano. Conclusões A exposição às diferentes cargas de trabalho submete os trabalhadores a inúmeros processos de desgaste, os quais devem ser monitorados para que sejam implementadas medidas preventivas.

Uudenvuodenpuhe (radiossa 1.1.1965)

Puhe

Hina 20.3.1944

Kirje

Edustajanvaalilain muutos

Puhe

What do the papers sell?

We model the market for news as a two-sided market where newspapers sell news to readers who value accuracy and sell space to advertisers who value advert-receptive readers. We show that monopolistic newspapers under-report or bias news that sufficiently reduces advertiser profits. Newspaper competition generally reduces the impact of advertising. In fact, as the size of advertising grows, newspapers may paradoxically reduce advertiser bias, due to increasing competition for readers. However, advertisers can counter this effect of competition by committing to news-sensitive cut-off strategies, potentially inducing as much under-reporting as in the monopoly case.

Precursors of functional MHC class I- or class II-restricted CD8alphaalpha(+) T cells are positively selected in the thymus by agonist self-peptides.

The origin and specificity of alphabeta TCR(+) T cells that express CD8alphaalpha have been controversial issues. Here we provide direct evidence that precursors of functional CD8alphaalpha T cells are positively selected in the thymus in the presence of agonist self-peptides. Like conventional positive selection, this agonist selection process requires functional TCR alpha-CPM, whereas it is independent of CD8beta expression. Furthermore, CD8alphaalpha expression on mature, agonist-selected T cells does not imply selection by MHC class I, and CD8alphaalpha(+) T cells can be either class I or class II restricted. Our data define a distinct agonist-dependent, positive selection process in the thymus, and they suggest a function for CD8alphaalpha distinct from the conventional TCR coreceptor function of CD8alphabeta or CD4.

Phenotype and function of protective T cell immune responses in HIV.

PURPOSE OF REVIEW: Definition of T cell immune correlates in HIV infection remains a lofty goal towards our understanding of the HIV-specific immune response. This review will focus upon recent developments and controversies in our understanding of protective T cell responses against HIV. RECENT FINDINGS: It has become clear that multiple functions and phenotypic markers of T cells must be assessed to accurately characterize the complexity of CD4 and CD8 T cell responses. While evidence indicates that a hallmark of protective immune responses in HIV infection is the presence of 'polyfunctional' T cell responses, a disconnect remains between the function and phenotype of effective HIV-specific T cells. Moreover, there may be inherent differences in the ability of specific human leukocyte antigen class I families to promote CD8 T cell effector versus polyfunctional responses. It remains to be determined how polyfunctional responses arise in HIV infection, which functions are important for control, and whether surface phenotype markers provide an indication of protective capacity. SUMMARY: Polyfunctional and phenotypic assessment of T cell responses have clearly advanced our understanding of HIV specific immune responses. Critical questions remain, however, especially whether polyfunctional T cell responses control, or are controlled by, HIV replication.

Carabid beetle assemblages in three environments in the Araucaria humid forest of southern Brazil

Carabid beetle assemblages in three environments in the Araucaria humid forest of southern Brazil. Carabidae is composed mainly by ground-dwelling predator beetles. It is the fourth most diverse group within Coleoptera, but its diversity in the Neotropical region is understudied. Here we describe and analyze the diversity of carabid beetles in a region of subtropical rain forest dominated by Araucaria angustifolia with different landscapes. Three areas were chosen in an environmental integrity gradient: primary forests, secondary forests and old Pinus plantations. Pitfall traps were taken monthly, in a total of 14 samples per area. 1733 adult carabid beetles, belonging to 18 species, were sampled. There were differences in richness and abundance between the sampled areas. The total scores followed the same tendency: primary forests (14 species/747 individuals), secondary forests (13/631) and Pinus forests (10/355). An analysis of similarity shows differences in species composition, for both areas and seasons. Galerita lacordarei was the most abundant species for all samples and seasons. Carabid species show similar responses in accordance with habitat heterogeneity and disturbance. The abundance of Galerita lacordarei was influenced by temperature, for all sampled sites. Environmental changes affect the carabid assemblages and decrease diversity, possibly interfering in local dynamics. Seasonality patterns seem to indicate an increase in individual movement during summer, probably in search of resources. It is suggested that microhabitat patchiness is probably an important factor affecting carabid beetle diversity at small spatial scales.