692 resultados para 1044
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1819/09/29 (N93)-1819/10/02.
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1819/11/18 (N107)-1819/11/20.
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1819/07/08 (N70)-1819/07/10.
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1819/04/15 (N46)-1819/04/17.
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1819/06/10 (N62)-1819/06/12.
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1819/04/29 (N50)-1819/04/30.
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1819/12/02 (N111)-1819/12/04.
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1819/12/29 (N126).
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1870/03/15 (Numéro 1044).
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Background: Most children with influenza are treated as outpatients but, especially among young children, influenza-attributable illnesses often result in hospitalization. However, relatively scarce data exist on the clinical picture and the full disease burden of pediatric influenza. Prompt diagnosis of influenza could enable the institution of antiviral therapy and adequate cohorting of patients. Data are needed to help clinicians correctly suspect influenza at the time of hospital admission. Aims and methods: We conducted a prospective 2-year cohort study of respiratory infections in children aged ≤13 years to determine the incidence of influenza in outpatient children and to assess the clinical presentation of influenza in various age groups seen in primary care. We also determined the rates of different complications attributable to influenza and the absenteeism of the children and their parents due to the child’s influenza infection. We then conducted a further 16-year retrospective study of children ≤16 years of age, hospitalized with virologically confirmed influenza. We estimated the population-based rates of hospitalizations and determined the primary admission diagnoses of the hospitalized children in different age groups. Results: The average annual rate of influenza was highest (179 / 1000) among children <3 years old. In this age group, acute otitis media was diagnosed as a complication of influenza in 40% of children. High fever was the most prominent sign of influenza, and 20% of children <3 years of age had a fever ≥40oC. Most children had rhinitis already during the first days of the illness. The average annual incidence of influenzarelated hospitalization was highest (276 / 100,000) among infants <6 months of age, of whom 52% were primarily admitted due to sepsis-like illnesses. Respiratory symptoms accounted for 38% of the hospitalizations. Conclusions: Influenza causes a substantial burden of illness on outpatient children and their families. The clinical presentation of influenza is most severe in children <3 years of age. The high incidence of influenza-associated hospitalizations among infants aged <6 months calls for more effective ways to prevent influenza in this age group. The clinical manifestations of influenza vary widely in different age groups of children at the time of hospital admission. Awareness of this phenomenon is important for the early recognition of the illness and the potential initiation of effective antiviral treatment of these patients.
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The objective of the present study was to assess the incidence, risk factors and outcome of patients who develop acute renal failure (ARF) in intensive care units. In this prospective observational study, 221 patients with a 48-h minimum stay, 18-year-old minimum age and absence of overt acute or chronic renal failure were included. Exclusion criteria were organ donors and renal transplantation patients. ARF was defined as a creatinine level above 1.5 mg/dL. Statistics were performed using Pearsons' chi2 test, Student t-test, and Wilcoxon test. Multivariate analysis was run using all variables with P < 0.1 in the univariate analysis. ARF developed in 19.0% of the patients, with 76.19% resulting in death. Main risk factors (univariate analysis) were: higher intra-operative hydration and bleeding, higher death risk by APACHE II score, logist organ dysfunction system on the first day, mechanical ventilation, shock due to systemic inflammatory response syndrome (SIRS)/sepsis, noradrenaline use, and plasma creatinine and urea levels on admission. Heart rate on admission (OR = 1.023 (1.002-1.044)), male gender (OR = 4.275 (1.340-13642)), shock due to SIRS/sepsis (OR = 8.590 (2.710-27.229)), higher intra-operative hydration (OR = 1.002 (1.000-1004)), and plasma urea on admission (OR = 1.012 (0.980-1044)) remained significant (multivariate analysis). The mortality risk factors (univariate analysis) were shock due to SIRS/sepsis, mechanical ventilation, blood stream infection, potassium and bicarbonate levels. Only potassium levels remained significant (P = 0.037). In conclusion, ARF has a high incidence, morbidity and mortality when it occurs in intensive care unit. There is a very close association with hemodynamic status and multiple organ dysfunction.
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1910/11/20 (Numéro 1044).
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1887/01/23 (Numéro 1044).
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Contient : a Acte, en latin, du roi CHARLES VIII. Le roi y anoblit Éloi Gigaud et sa postérité. Éloi Gigaud est dit demeurer « in parrochia de Mehers, prope Castriam, in provincia Bituriae ». Plessis lez Tours, mai 1489 ; b Note concernant la famille Nicolay, de 1440 à 1588, où l'on examine à quelle date la qualité de noble à été donnée à Jean Nicolay, père du premier Nicolay qui fut « premier president aux comptes à Paris ». On a joint à cette note la copie de trois actes, en latin, des années 1452, 1469, 1522. Jean Nicolay figure dans les deux premiers, et son fils, le premier président, dans le troisième ; c Acte par lequel le roi LOUIS XIV déclare légitimés ses enfants naturels Louis-Auguste, duc du Maine, Louis-César, comte du Vexin, Louise-Françoise de Nantes. St-Germain-en-Laye, décembre 1673 ; d Le « lieu de Mouchy le Vieil », donné à « Jean, bastard de Tyen, bailly de Senlis, au mois de juin 1422 » ; e « Me Jean Bruslard,... ordonné avocat... du roy en la prevosté de Chastillon sur Marne, par lettres du roy du 28 fevrier 1423 » ; f La famille de Jeanne d'Arc. 1429 et 1473 ; g Un mandement du roi Louis XI « au seigneur de La Roche-Guyon », pour « laisser passer 60 tonneaux de vin », envoyés par ledit roi au roi d'Angleterre, Henri VI. Paris, 16 nov. 1470
