936 resultados para delayed match-to-sample
Resumo:
Climate change projections are usually presented as 'snapshots' of change at a particular time in the future. Instead, we consider the key question 'when will specific temperature thresholds will be exceeded?'. Framing the question as "when might something happen (either permanently or temporarily)?" rather than "what might happen?" demonstrates that lowering future emissions will delay the crossing of temperature thresholds and buy valuable time for planning adaptation. For example, in higher greenhouse gas emission scenarios, a global average 2°C warming threshold is likely to be crossed by 2060, whereas in a lower emissions scenario, the crossing of this threshold is delayed up to several decades. On regional scales, however, the 2°C threshold will probably be exceeded over large parts of Eurasia, North Africa and Canada by 2040 if emissions continue to increase- well within the lifetime of many people living now.
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In the mid-1990s the subpolar gyre of the North Atlantic underwent a remarkable rapid warming, with sea surface temperatures increasing by around 1C in just 2 years. This rapid warming followed a prolonged positive phase of the North Atlantic Oscillation (NAO), but also coincided with an unusually negative NAO index in the winter of 1995/96. By comparing ocean analyses and carefully designed model experiments we show that this rapid warming can be understood as a delayed response to the prolonged positive phase of the NAO, and not simply an instantaneous response to the negative NAO index of 1995/96. Furthermore, we infer that the warming was partly caused by a surge, and subsequent decline, in the Meridional Overturning Circulation and northward heat transport of the Atlantic Ocean. Our results provide persuasive evidence of significant oceanic memory on multi-annual timescales, and are therefore encouraging for the prospects of developing skillful predictions.
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The goal of this paper is to study and further develop the orthogonality sampling or stationary waves algorithm for the detection of the location and shape of objects from the far field pattern of scattered waves in electromagnetics or acoustics. Orthogonality sampling can be seen as a special beam forming algorithm with some links to the point source method and to the linear sampling method. The basic idea of orthogonality sampling is to sample the space under consideration by calculating scalar products of the measured far field pattern , with a test function for all y in a subset Q of the space , m = 2, 3. The way in which this is carried out is important to extract the information which the scattered fields contain. The theoretical foundation of orthogonality sampling is only partly resolved, and the goal of this work is to initiate further research by numerical demonstration of the high potential of the approach. We implement the method for a two-dimensional setting for the Helmholtz equation, which represents electromagnetic scattering when the setup is independent of the third coordinate. We show reconstructions of the location and shape of objects from measurements of the scattered field for one or several directions of incidence and one or many frequencies or wave numbers, respectively. In particular, we visualize the indicator function both with the Dirichlet and Neumann boundary condition and for complicated inhomogeneous media.
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We present the results of simulations carried out with the Met Office Unified Model at 12km, 4km and 1.5km resolution for a large region centred on West Africa using several different representations of the convection processes. These span the range of resolutions from much coarser than the size of the convection processes to the cloud-system resolving and thus encompass the intermediate "grey-zone". The diurnal cycle in the extent of convective regions in the models is tested against observations from the Geostationary Earth Radiation Budget instrument on Meteosat-8. By this measure, the two best-performing simulations are a 12km model without convective parametrization, using Smagorinsky style sub-grid scale mixing in all three dimensions and a 1.5km simulations with two-dimensional Smagorinsky mixing. Of these, the 12km model produces a better match to the magnitude of the total cloud fraction but the 1.5km results in better timing for its peak value. The results suggest that the previously-reported improvement in the representation of the diurnal cycle of convective organisation in the 4km model compared to the standard 12km configuration is principally a result of the convection scheme employed rather than the improved resolution per se. The details of and implications for high-resolution model simulations are discussed.
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Insect pollinators provide a critical ecosystem service by pollinating many wild flowers and crops. It is therefore essential to be able to effectively survey and monitor pollinator communities across a range of habitats, and in particular, sample the often stratified parts of the habitats where insects are found. To date, a wide array of sampling methods have been used to collect insect pollinators, but no single method has been used effectively to sample across habitat types and throughout the spatial structure of habitats. Here we present a method of ‘aerial pan-trapping’ that allows insect pollinators to be sampled across the vertical strata from the canopy of forests to agro-ecosystems. We surveyed and compared the species richness and abundance of a wide range of insect pollinators in agricultural, secondary regenerating forest and primary forest habitats in Ghana to evaluate the usefulness of this approach. In addition to confirming the efficacy of the method at heights of up to 30 metres and the effects of trap color on catch, we found greatest insect abundance in agricultural land and higher bee abundance and species richness in undisturbed forest compared to secondary forest.
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This letter presents an accurate delay analysis in prioritised wireless sensor networks (WSN). The analysis is an enhancement of the existing analysis proposed by Choobkar and Dilmaghani, which is only applicable to the case where the lower priority nodes always have packets to send in the empty slots of the higher priority node. The proposed analysis is applicable for any pattern of packet arrival, which includes the general case where the lower priority nodes may or may not have packets to send in the empty slots of the higher priority nodes. Evaluation of both analyses showed that the proposed delay analysis has better accuracy over the full range of loads and provides an excellent match to simulation results.
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While there has been a fair amount of research investigating children’s syntactic processing during spoken language comprehension, and a wealth of research examining adults’ syntactic processing during reading, as yet very little research has focused on syntactic processing during text reading in children. In two experiments, children and adults read sentences containing a temporary syntactic ambiguity while their eye movements were monitored. In Experiment 1, participants read sentences such as, ‘The boy poked the elephant with the long stick/trunk from outside the cage’ in which the attachment of a prepositional phrase was manipulated. In Experiment 2, participants read sentences such as, ‘I think I’ll wear the new skirt I bought tomorrow/yesterday. It’s really nice’ in which the attachment of an adverbial phrase was manipulated. Results showed that adults and children exhibited similar processing preferences, but that children were delayed relative to adults in their detection of initial syntactic misanalysis. It is concluded that children and adults have the same sentence-parsing mechanism in place, but that it operates with a slightly different time course. In addition, the data support the hypothesis that the visual processing system develops at a different rate than the linguistic processing system in children.
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The components of many signaling pathways have been identified and there is now a need to conduct quantitative data-rich temporal experiments for systems biology and modeling approaches to better understand pathway dynamics and regulation. Here we present a modified Western blotting method that allows the rapid and reproducible quantification and analysis of hundreds of data points per day on proteins and their phosphorylation state at individual sites. The approach is of particular use where samples show a high degree of sample-to-sample variability such as primary cells from multiple donors. We present a case study on the analysis of >800 phosphorylation data points from three phosphorylation sites in three signaling proteins over multiple time points from platelets isolated from ten donors, demonstrating the technique's potential to determine kinetic and regulatory information from limited cell numbers and to investigate signaling variation within a population. We envisage the approach being of use in the analysis of many cellular processes such as signaling pathway dynamics to identify regulatory feedback loops and the investigation of potential drug/inhibitor responses, using primary cells and tissues, to generate information about how a cell's physiological state changes over time.
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[1] Iron is hypothesized to be an important micronutrient for ocean biota, thus modulating carbon dioxide uptake by the ocean biological pump. Studies have assumed that atmospheric deposition of iron to the open ocean is predominantly from mineral aerosols. For the first time we model the source, transport, and deposition of iron from combustion sources. Iron is produced in small quantities during fossil fuel burning, incinerator use, and biomass burning. The sources of combustion iron are concentrated in the industrialized regions and biomass burning regions, largely in the tropics. Model results suggest that combustion iron can represent up to 50% of the total iron deposited, but over open ocean regions it is usually less than 5% of the total iron, with the highest values (< 30%) close to the East Asian continent in the North Pacific. For ocean biogeochemistry the bioavailability of the iron is important, and this is often estimated by the fraction which is soluble ( Fe(II)). Previous studies have argued that atmospheric processing of the relatively insoluble Fe(III) occurs to make it more soluble ( Fe( II)). Modeled estimates of soluble iron amounts based solely on atmospheric processing as simulated here cannot match the variability in daily averaged in situ concentration measurements in Korea, which is located close to both combustion and dust sources. The best match to the observations is that there are substantial direct emissions of soluble iron from combustion processes. If we assume observed soluble Fe/black carbon ratios in Korea are representative of the whole globe, we obtain the result that deposition of soluble iron from combustion contributes 20-100% of the soluble iron deposition over many ocean regions. This implies that more work should be done refining the emissions and deposition of combustion sources of soluble iron globally.
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Polycarbonate membranes (PCM) of various pores sizes (400, 200, 100 and 50 nm) were used as templates for gold deposition. The electrodeposition from gold ions resulted in the formation of gold nanotubes when large pores size PCMs (400 and 200 nm) were used. On the other hand, gold nanowires were predominant for the PCMs with smaller pores size (100 and 50 nm). Surface-enhanced Raman scattering (SERS) from the probe molecule 4-mercaptopyridine (4-MPy) was obtained from all these nanostructures. The SERS efficiency of the substrates produced using the PC M templates were compared to two commonly used SERS platforms: a roughened gold electrode and gold nanostructures electrodeposited through organized polystyrene spheres (PSS). The SERS signal of the probe molecule increased as the pore diameter of the PCM template decreased. Moreover, the SERS efficiency from the nanostructures produced using 50 nm PCM templates was four and two times better than the signal from the roughened gold electrode and the PSS template, respectively. The SERS substrates prepared using PCM templates were more homogenous over a larger area (ca. 1 cm(2)), presented better spatial and sample to sample reproducibility than the other substrates. These results show that SERS substrates prepared using PCM templates are promising for the fabrication of planar SERS platforms for analytical/bioanalytical applications.
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Introdução e Objetivos: O sistema nervoso central (SNC) é o um sítio freqüente de recaída na criança com leucemia linfocítica aguda (LLA). Existe evidência de que a punção lombar traumática (PLT) pode representar um risco adicional de recaída no SNC quando ocorre inoculação de blastos no liqüido céfalorraquidiano (LCR). Este estudo tem por objetivo determinar se a ocorrência da PLT ao diagnóstico afeta o prognóstico de pacientes com essa patologia. Material e Métodos: Setenta e sete pacientes com diagnóstico de LLA, tratados entre 1992 a 2002, foram incluídos na análise. Quimioterapia intratecal (QIT) foi instilada imediatamente após a PL inicial (precoce), ou na segunda PL (tardia), realizada no período de 24 a 48 horas após a realização da PL inicial. Foi feita análise da influência da PLT e do momento (precoce x tardia) de administração da QIT em relação a recaída no SNC. Resultados: Entre os 19 pacientes que apresentaram PLT ao diagnóstico e receberam QIT tardia, seis tiveram recaída isolada no SNC e dois recaída combinada em SNC e medula óssea (MO). Entre os nove pacientes que tiveram PLT e receberam QIT precoce, somente um apresentou recaída combinada em SNC e MO (P=0,20); não houve, portanto, influência estatisticamente significativa da PLT na sobrevida livre de eventos (SLE) (55% para QIT precoce x 49% para QIT tardia) (P=0,37). Entretanto, em análise estratificada, de acordo com grupos de risco, observamos que para pacientes de baixo ou médio risco o OR foi de 0,8 quando recebiam QIT tardia (P=0,99) e 0,17 quando recebiam QIT precoce (P=0,47). Por outro lado, entre pacientes de alto risco o OR para recaída foi de 21,0 para aqueles que recebiam QIT tardia (P=0,09) e 1,5 para o grupo que recebia Q IT precoce (P=0,99). Conclusão: Os resultados do presente estudo são sugestivos de que a ocorrência da PLT tem uma influência adversa no prognóstico de pacientes com LLA de alto risco de recaída. Como estes resultados são decorrentes de um estudo retrospectivo, recomenda-se que sejam confirmados em estudos prospectivos randomizados.
Resumo:
o presente tema - "Agressão no jogo de futebol” - teve primeiramente como objetivo investigar o problema da agressão no esporte popular brasileiro. Assim sendo o trabalho oferece uma visão introdutória, exploratória e descritiva dos aspectos principais com relação ao problema. Desta forma a análise está ligada a várias opiniões e posições que já foram expressas por um número de autores, e esta nossa análise está intimamente ligada a tudo que já foi publicado sobre este tema. Contudo, apresentamos uma ligeira inovação, uma contribuição muito especial. Ao dissertarmos de uma maneira, a mais clara possível, nos limitamos num ponto especifico que é o de vivermos a realidade do jogo de futebol. Cuidadosamente, conduzimos o tema principal do trabalho em direção ao papel fundamental dos dirigentes, treinadores, médicos desportistas, juizes de campo, preparadores físicos, advogados desportistas e psicólogos. Em suma, nós conduzimos nossa atenção ,para as pessoas diretamente envolvidas com a prática do esporte em geral na sociedade contemporânea, assim como da luta para combater os problemas cria dos pela agressão, aspecto particularmente relevante para os jogadores de futebol em situações de forte competição. Na segunda parte do trabalho, nós tivemos a oportunidade de fazer alguns contatos diretos 'e pessoais com vários jogadores conhecidos do futebol no Brasil, assim como outros tipos de profissionais que lidam com este esporte. Podemos dizer, que tal ordem de contatos foi desenvolvida através de, várias observações não só na hora dos treinos, mas também durante um número de jogos eliminatórios (finais), juntamente com algumas entrevistas individuais que depois eles concederam. Quando todas as peças foram colocadas nos próprios lugares é que o quadro ficou mais completo, expondo os fatores mútuos e interativos nos jogos. Falando de maneira geral, o modelo de melhor compreensão proposto para este trabalho foi detalhado de forma que pode ser baseado na observação direta da pesquisa de campo mas com um número especifico de dados para este tipo de· pesquisa, cujos principais objetivos foram as simples situações corriqueiras (significatiyas). Com este material, em nossas mãos, nós pudemos reformular algumas questões vitais que poderiam enriquecer o dia-a-dia da psicologia neste campo de conhecimento. Sem dúvida, essa ênfase atual da questão da agressão - e um problema crescente. O significado do combate a agressão não é fácil, digamos, de enquadrar numa simples elaboração de palavras. Na pesquisa que fizemos a conclusão é de que a agressão deve ser combatida desde muito cedo nos estágios das "escolas de futebol".
Resumo:
O modelo racional de decisão tem sido objeto de estudo constante na academia de vários países, contribuindo para evolução do ser racional como importante tomador de decisão. A evolução destes estudos tem aberto questionamentos quanto à capacidade de racionalidade que temos como tomadores de decisão, deleitando assim em várias teorias novas que pesquisam estas limitações no decidir. Especialmente aplicadas a teorias econômicas, estudos como Inteligência Artificial, Contabilidade Mental, Teoria dos Prospectos, Teoria dos Jogos entre outras se destacam neste cenário de estudo das finanças comportamentais. A contabilidade como ferramenta de apoio as decisões financeiras ocupa posição de destaque. Esta tem em seu escopo de trabalho normas (aquilo que deveria ser feito) que regulam sua atuação, em alguns casos esta regulamentação não é precisa em suas especificações, deixando janelas que levam seus profissionais a erros de interpretação. A imprecisão contábil pode causar viés em suas classificações. Os profissionais, deparados com este legado podem se utilizar de heurísticas para interpretar da melhor maneira possível os acontecimentos que são registrados na contabilidade. Este trabalho tem a intenção de análise de alguns pontos que consideramos importantes quando temos imprecisão contábil, respondendo as seguintes perguntas: a imprecisão de normas contábeis causa viés na decisão? O profissional que se depara com imprecisão contábil se utiliza de Heurística para decidir? Quais os erros mais comuns de interpretação sob incerteza contábil? Para que o assunto fosse abordado com imparcialidade de maneira a absorver retamente quais são as experiências dos profissionais que atuam na área contábil, foi elaborado um questionário composto por uma situação possível que leva o respondente a um ambiente de tomada de decisões que envolva a prática contábil. O questionário era dividido em duas partes principais, com a preocupação de identificar através das respostas se existe imprecisão contábil (sob a luz do princípio da prudência) e quais heurísticas que os respondentes se utilizam com mais freqüência, sendo o mesmo aplicado em profissionais que atuam na área contábil e que detenham experiências profissionais relacionadas à elaboração, auditoria ou análise de demonstrações contábeis. O questionário aplicado na massa respondente determinou, através das respostas, que existe, segundo os profissionais, interpretações diferentes para os mesmos dados, caracterizando assim zona cinzenta, segundo Penno (2008), ou seja, interpretações que podem ser mais agressivas ou mais conservadoras conforme a interpretação do profissional. Já quanto às estratégias simplificadoras, ou heurísticas, que causam algum tipo de enviesamento no processo decisório, alguns foram identificadas como: associações pressupostas, interpretação errada da chance, regressão a media e eventos disjuntivos e eventos conjuntivos, que reforçam a pesquisa dando indícios de que os respondentes podem estar tomando decisões enviesadas. Porém, não se identificou no estudo tomada de decisões com enviesamentos como recuperabilidade e insensibilidades ao tamanho da amostra. Ao final do estudo concluímos que os respondentes têm interpretações diferenciadas sobre o mesmo assunto, mesmo sob a luz do princípio contábil da prudência, e ainda se utilizam de estratégias simplificadoras para resolverem assuntos quotidianos.
Resumo:
The study object of this thesis intertwines the history of deaf education in the last 30 years in three schools for the deaf in the cities of Campina Grande, Gado Bravo and Aroeiras, Paraiba, the life stories of six deaf teachers of brasilian sign language (Libras) that have formed and works in these educational institutions for the deaf and our own journey, as a teacher and researcher. The study was conducted on the theoretical-methodological principles of (auto)biographical research in education and socio-historical studies on the social formation of the human. The corpus used for analysis was consisted of six narrative interviews conducted in sign language and transcribed into portuguese, documents and personal files and institutional. The analysis allowed us to define three hinge moments of this story: the creation of the first school for the deaf, within the framework of oralism (1980 - 1991), the passage into the Total Communication (1991 - 1995) and, finally, the introduction of Bilingualism (1995 to today). The analyzes show that the trajectories of teacher formation of the research participants reflect the history of the three schools which have costituted bilingual social spaces of paramount importance to the subjects and the deaf community as a group of linguistic and cultural minority. The evolution of this trajectory has allowed to demarcate between the two generations of research participants. The generation of heirs of oralism, which had delayed access to the Libras and lived an education referenced in oralism, whose reminiscences of childhood and adolescence are strongly marked by suffering for the lack of communication, which hinders their social and professional career until today. And the generation of the sons of bilingualism, the youngest in age, who had childhood access to Libras and education within the framework of bilingualism, whose reminiscences are not marked by suffering and have a positive vision of the future. With respect to your teacher formation, three figures stand out as a teacher. The teacher's improvised, closer to the first generation of teachers who were called to teach without proper training. The figure of the teacher craftsman, which corresponds to the image that most of them have of yourself now, understanding that their knowledge are based on the exchange between peers. And finally the figure of the real teacher, which stands on the horizon of expectations as future graduates in Letters |Libras. The narratives allowed to realize that the evolution between these figures is based on the contributions of the other: hearing teachers of EDAC and the Federal University of Campina Grande and deaf teachers of the two generations who learn from each other. The analyzes and reflections allowed to defend the thesis of the centrality of bilingual environments for the establishment of the deaf person as a citizen with full rights, based on the voice of the deaf, muted by the history of education, conducted by listeners
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Unlike adult cancer, where cells usually originate from epithelial tissue and is linked to environmental factors, malignant tumors in childhood are mostly of embryonic origin and have a phase of rapid proliferation. When not started chemotherapy at this stage, the tumor increases in size, reducing their growth rate, thus reducing the response to chemotherapy. Childhood cancer is in Brazil, the second cause of mortality among children and adolescents from one to nineteen. His impact on the ranking of diseases becomes significantly important to public health since the first issue is related to accidents and violence. Many children are still sent to the centers of high complexity for cancer treatment with advanced stage disease. The delay in referral to diagnosis can be family, or the difficulty of access to the health sector, or the characteristics of the disease and lack of health staff regarding theme of childhood cancer. Before this problem, we aimed to assess the performance of health teams in the identification of child and adolescent symptoms of cancer in primary care, through the action research methodology, which includes the teaching-learning, seminars, describing the actions of the group and discussing the activities after the training. This study involved thirty-seven health professionals who provide care for children and adolescents in the USF Felipe Shrimp II, the Support Center for Children with Cancer and the pediatric hospital UFRN during the period from March to December 2010. The data were analyzed simultaneously to evaluate actions, following the direction of the analysis of ideas Freires, having as theoretical reference the primary health care. The diagnosis of current reality, as knowledge of the health team targeted for early identification of signs and symptoms raised through questioning, presented as generative themes: resistance to change, awareness of the need for apprehension of knowledge; prior knowledge through the media, fragmentation of the healthcare network, interfering with the operation of the reference and counter, the stigma of death, among others. The selected themes enabled the choice of content for the preparation of four seminars, such as implementation of collective action for discussion problematical. The teaching-learning process has allowed the study participants awareness of the problem and work through the knowledge acquired by interfering in decreasing the time interval between the identification of signs and symptoms of cancer and early specialist treatment. Their difficulties we are faced with a diagnosis of terminal cancer and associated with delayed access to laboratory tests and imaging necessary for the diagnosis of neoplasms. Thus, we find that when the team is consciously involved in the education process from identification of the problem situation, there may be significant changes in daily activities through awareness of being. However, we also realize that acquisition of knowledge and interest of the team are not enough, since to be efficiency of our service, we need an organization of cancer care network operating in the state of Rio Grande do Norte