Diversity in levels of intracellular total creatine and triglycerides in human skeletal muscles observed by 1H-MRS

We used1H-magnetic resonance spectroscopy to noninvasively determine total creatine (TCr), choline-containing compounds (Cho), and intracellular (IT) and extracellular (between-muscle fibers) triglycerides (ET) in three human skeletal muscles. Subjects' (n = 15 men) TCr concentrations in soleus [Sol; 100.2 ± 8.3 (SE) mmol/kg dry wt] were lower (P < 0.05) than those in gastrocnemius (Gast; 125.3 ± 9.2 mmol/kg dry wt) and tibialis anterior (TA; 123.7 ± 8.8 mmol/kg dry wt). The Cho levels in Sol (35.8 ± 3.6 mmol/kg dry wt) and Gast (28.5 ± 3.5 mmol/kg dry wt) were higher (P < 0.001 andP < 0.01, respectively) compared with TA (13.6 ± 2.4 mmol/kg dry wt). The IT values were found to be 44.8 ± 4.6 and 36.5 ± 4.2 mmol/kg dry wt in Sol and Gast, respectively. The IT values of TA (24.5 ± 4.5 mmol/kg dry wt) were lower than those of Sol (P < 0.01) and Gast (P < 0.05). There were no differences in ET [116.0 ± 11.2 (Sol), 119.1 ± 18.5 (Gast), and 91.4 ± 19.2 mmol/kg dry wt (TA)]. It is proposed that the differences in metabolite levels may be due to the differences in fiber-type composition and deposition of metabolites due to the adaptation of different muscles during locomotion.

Body fat MRS

The increasing levels of obesity, and its associated comorbidities, have prompted a reassessment of the techniques used for assessing body fat, including content, distribution, and composition. Magnetic resonance spectroscopy (MRS) is one among the many invaluable in vivo tools available today to evaluate the role of body fat in health and disease. However, although MRS has become a powerful technique for assessing ectopic fat in vivo, it has had limited use in other areas of research associated with body fat. MRS has found some success as a fast method to determine whole body adiposity in rodent models of disease, as well as a noninvasive method of obtaining an index of the overall composition of body fat in human subjects. Its more significant use has been in the understanding of bone marrow fat content, where important advances have been made, especially in longitudinal studies. In conclusion, in the area of body fat, MRS continues to be an adjunct technique to more precise and versatile MRI methods.

[Le] général [de l'armée du salut William Bramwell] Booth [serrant la main de sa fille Mary B. Booth] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 58688

Mrs Powers sur un éléphant [de la troupe des Powers elephants] à New-York : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 58885

Mrs Carrie Chapman, président[e] de la ligue internationale du suffrage féminin (cliché C.N. New-York) : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 59248

Gringalette / Jules Mary

Collection : Les Maîtres du roman populaire ; 1

Mary Pickford et Douglas Fairbanks arrivent à Southampton : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 59805

Miss Hollman [i. e. Dorothy Holman], 30-5-20 [finale double dames du championnat du monde à Saint-Cloud avec Mrs Satterthwaite] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 59468

Miss Hollman [i. e. Dorothy Holman], 30-5-20 [finale double dames du championnat du monde à Saint-Cloud avec Mrs Satterthwaite] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 59469