304 resultados para Markievicz, Constance


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A large number of later Neolithic sites (3900–3500BC) in Switzerland, Southern Germany and Eastern France offer outstandingly well preserved archaeological materials from cultural layers. Due to the wide use of dendrochronology, settlement remains and artefact assemblages can now be placed into a precise and fixed chronological framework, thus presenting a unique case within prehistoric archaeology. In earlier research, chronological and regional units were constructed on the basis of pottery. These spacial and temporal units of typical pottery sets were understood as Neolithic cultures, as culturally more or less homogenous entities connected with (ethnic) identities. Today, with a larger data corpus of excavated settlements at hand, we can begin to understand that this period of the past was in fact characterised by a multitude of cultural entanglements and transformations. This is indicated by the occurrence of local and non-local pottery styles in one and the same settlement: for example typically local Cortaillod pottery is found together with NMB-styled pottery in settlements at Lake Neuchâtel or Michelsberg pottery is regularly occurring in settlements at Lake Constance where Pfyn pottery style is the typical local one. These and many more examples show that there must have been complex entanglements of social ties expanding between Eastern France, Southern Germany and the Swiss Plateau. Given these circumstances the former notions of Neolithic culture should be critically revised. Therefore, in late 2014, the Prehistoric Archaeology Department at the Archaeological Institute of University of Berne started a four-year research project funded by Swiss National Science Foundation in late 2014: ‘Mobilities, Entanglements and Transformations in Neolithic Societies of the Swiss Plateau (3900-3500 BC)’. It’s objective is to address the topic sketched above by adopting a mixed methods research (MMR)-design combining qualitative and quantitative approaches from archaeology and archaeometry. The approach is theoretically based on Pierre Bourdieu’s reflexive sociology and his concept of habitus but includes further concepts of practice theories. By shifting the focus to the movement of people, ideas and things – to pottery production practices in contexts of mobility – a deeper understanding of the transformative capacities of encounters can be achieved. This opens the path for new insights of Neolithic societies including social, cultural and economic dynamics that were underestimated in former research.

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The anti-inflammatory effects of high-dose salicylates are well recognized, incompletely understood and unlikely due entirely to cyclooxygenase (COX) inhibition. We have previously reported a role for activation of the kinase Erk in CD11b/CD18 integrin-dependent adhesiveness of human neutrophils, a critical step in inflammation. We now report the effects of salicylates on neutrophil Erk and adhesion. Exposure of neutrophils to aspirin or sodium salicylate (poor COX inhibitor) inhibited Erk activity and adhesiveness of formylmethionyl-leucyl-phenylalanine- and arachidonic acid-stimulated neutrophils, consistent with anti-inflammation but not COX inhibition (IC50s = 1–8 mM). In contrast, indomethacin blocked neither Erk nor adhesion. Inhibition of Mek (proximal activator of Erk) also blocked stimulation of Erk and adhesion by formylmethionyl-leucyl-phenylalanineand arachidonic acid. Salicylate inhibition of Erk was independent of protein kinase A activation and generation of extracellular adenosine. These data are consistent with a role for Erk in stimulated neutrophil adhesion, and suggest that anti-inflammatory effects of salicylates may be mediated via inhibition of Erk signaling required for integrin-mediated responses.

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In 1991, Bryant and Eckard estimated the annual probability that a cartel would be detected by the US Federal authorities, conditional on being detected, to be at most between 13 % and 17 %. 15 years later, we estimated the same probability over a European sample and we found an annual probability that falls between 12.9 % and 13.3 %. We also develop a detection model to clarify this probability. Our estimate is based on detection durations, calculated from data reported for all the cartels convicted by the European Commission from 1969 to the present date, and a statistical birth and death process model describing the onset and detection of cartels.

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Mode of access: Internet.

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Standing (Adults) L-R: Marion Waterhouse Angell (Mrs. J.R.); James Rowland Angell; Andrew C. McLaughlin; Fanny C. Cooley. Angell (Mrs. A.C.); Alexis Caswell Angell; Sarah Caswell Angell (daughter of A.C), Lois Angell McLaughlin

Middle Row: James Waterhouse Angell (son of J.R.), Marion Angell (McAlpin) (daughter of James R.) James Burrill Angell, Isabel McLaughlin

Front Row: Constance McLaughlin (Green); Robert Cooley Angell (son of A.C.); Esther Lois McLaughlin (Donahue) David Blair McLaughlin; Rowland Hazard McLaughlin; James Burrill Angell II (son of A.C.): James Angell McLaughlin

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Cover title.

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Sir Walter Shaw, chairman.

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First vol. (through 1950) compiled by M.R. Burks and J.H. Schilling; 1951-55 and 1956-60 by C.F. and J.H. Schilling: 1961-65 by T. Ray; 1966-70 by M.A. and H.H. Koehn; 1971-75 by J.R. Wright and J.A. Russell; 1976-80 by Dana M. Adkins-Heljeson and Candace L. Holts.

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Accompanied by "Reference books of 1935/37- An informal supplement to Guide to reference books, sixth edition, by Isadore Gilbert Mudge." (v. 24 cm.) Published: Chicago, American Library association, 1939-

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Mode of access: Internet.

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Editors: 1893-Mar. 1897, Constance G. DuBois.--June 1897-Oct. 1898, G.H. Hicks.--Dec. 1898-Dec. 1900, T.A. Williams and C.L. Shear.

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Cover title.