Developing intermediate vocabulary.

Libro para estudiantes de inglés como lengua extranjera de nivel intermedio que les permite descubrir, aprender y practicar palabras y frases en contextos reales. Puede ser usado en clase por los profesores como libro de apoyo, en casa como deberes, o para estudiar por cuenta propia. Incluye veinte lecciones basadas cada una en un tema con textos reales seleccionados para captar el interés de los alumnos, ejercicios prácticos de construcción de palabras y colocación, verbos compuestos y modismos. Al final del libro hay un apartado con las soluciones.

English result : pre-intermediate photocopiable resource book.

Libro y DVD con material de apoyo para el profesor en la enseñanza del inglés como lengua extranjera en el nivel pre-intermedio (A2 del marco común europeo de referencia para las lenguas). Contiene cuarenta y ocho actividades para practicar gramática y vocabulario, dando la oportunidad a los alumnos de describir, explicar, especular, debatir y preguntar en inglés. Y dieciocho hojas de trabajo para usar con los clips documentales y entrevistas reales del DVD. Incluye instrucciones completas para el profesor de cada actividad y las soluciones a los ejercicios.

English result : intermediate photocopiable resource book.

Libro y DVD con material de apoyo para el profesor en la enseñanza del inglés como lengua extranjera en el nivel intermedio (B1 del marco común europeo de referencia para las lenguas). Contiene cuarenta y ocho actividades para practicar gramática y vocabulario, dando la oportunidad a los alumnos de describir, explicar, especular, debatir y preguntar en inglés. Y dieciocho hojas de trabajo para usar con los clips documentales y entrevistas reales del DVD. Incluye instrucciones completas para el profesor de cada actividad y las soluciones a los ejercicios.

English result : upper-intermediate photocopiable resource book.

Libro y DVD con material de apoyo para el profesor en la enseñanza del inglés como lengua extranjera en el nivel intermedio-alto (B2 del marco común europeo de referencia para las lenguas). Contiene cuarenta actividades para practicar gramática y vocabulario, dando la oportunidad a los alumnos de describir, explicar, especular, debatir y preguntar en inglés. Y quince hojas de trabajo para usar con los clips documentales y entrevistas reales del DVD. Incluye instrucciones completas para el profesor de cada actividad y las soluciones a los ejercicios.

English grammar in use : a self-study reference and practice book for intermediate students of Enlighs.

Libro orientado al auto-estudio para alumnos de nivel intermedio de inglés. Está estructurado en ciento cuarenta y cinco lecciones, cada una sobre un tema determinado de gramática inglesa, con su explicación y ejemplos en la página izquierda y ejercicios para practicar en la página derecha. Al final del libro hay una sección con las soluciones, siete apéndices sobre verbos regulares e irregulares, formas verbales para el presente y pasado, formas verbales para el futuro, verbos modales, contracciones, ortografía e inglés americano, un apartado con ejercicios adicionales que concentran varios temas de gramática en un mismo ejercicio, y una guía de estudio para ayudar a decidir qué temas repasar. Incluye un cd-rom con más ejercicios y mil setecientas preguntas de examen.

Using problem-based learning for introducing producer theory and market structure in intermediate microeconomics

This paper shows how instructors can use the problem‐based learning method to introduce producer theory and market structure in intermediate microeconomics courses. The paper proposes a framework where different decision problems are presented to students, who are asked to imagine that they are the managers of a firm who need to solve a problem in a particular business setting. In this setting, the instructors’ role is to provide both guidance to facilitate student learning and content knowledge on a just‐in‐time basis

Formation and circulation of the cold intermediate layer in the Gulf of Saint Lawrence

[ 1] The local heat content and formation rate of the cold intermediate layer (CIL) in the Gulf of Saint Lawrence are examined using a combination of new in situ wintertime observations and a three-dimensional numerical model. The field observations consist of five moorings located throughout the gulf over the period of November 2002 to June 2003. The observations demonstrate a substantially deeper surface mixed layer in the central and northeast gulf than in regions downstream of the buoyant surface outflow from the Saint Lawrence Estuary. The mixed-layer depth in the estuary remains shallow (< 60 m) throughout winter, with the arrival of a layer of near-freezing waters between 40 and 100 m depth in April. An eddy-permitting ice-ocean model with realistic forcing is used to hindcast the period of observation. The model simulates well the seasonal evolution of mixed-layer depth and CIL heat content. Although the greatest heat losses occur in the northeast, the most significant change in CIL heat content over winter occurs in the Anticosti Trough. The observed renewal of CIL in the estuary in spring is captured by the model. The simulation highlights the role of the northwest gulf, and in particular, the separation of the Gaspe Current, in controlling the exchange of CIL between the estuary and the gulf. In order to isolate the effects of inflow through the Strait of Belle Isle on the CIL heat content, we examine a sensitivity experiment in which the strait is closed. This simulation shows that the inflow has a less important effect on the CIL than was suggested by previous studies.

Quality of medicines stored together in multi-compartment compliance aids

Background and Objective: Dispensing medicines into compliance aids is a common practice in pharmacy contrary to manufacturers’ advice and studies have shown the appearance of light-sensitive tablets is compromised by such storage; we previously found evidence of reduced bioavailability at elevated temperature and humidity. Our objective was to examine the physicochemical stability of two generic atenolol tablets in different compliance aids and with aspirin co-storage at room temperature and at 40 °C/75% relative humidity. Methods: The physicochemical stability of atenolol tablets was evaluated after 28 days of storage and compared with controls by examining visual appearance, weight, disintegration, dissolution, friability and hardness to accepted standards and using a previously validated HPLC method for chemical assay. Results and Discussion: The response to storage was brand-dependent and not straightforward. With one make of atenolol (Alpharma), storage in compliance aids even at room temperature impacted on physical stability, reducing tablet hardness, with storage in Dosett® exerting a greater impact than storage in Medidos® (t-test P < 0·001). Co-storage at elevated temperature and humidity also impacted on the appearance of non-coated aspirin tablets (Angette™). The chemical stability of atenolol was not affected and we did not find evidence of changes to bioavailability with either make. Certainly data for one atenolol make (CP Pharmaceuticals) co-stored with aspirin (Angette™ and Nu-Seals) in both compliance aids at room temperature provided evidence of short-term stability. But medicines are dispensed into compliance aids in multi-factorial ways so our study highlights not only the lack of evidence but also a realization that evidence to support real practice may not be accomplished through research. Conclusion: Reassuring practitioners of the continued stability of medicines in compliance aids under the countless condition in which they are dispensed in practice may requires a different approach involving medical device regulators and more definitive professional guidance.