393 resultados para Hollis
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"Reprinted August 1985."
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Mode of access: Internet.
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Thesis (Master's)--University of Washington, 2016-06
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This paper presents a new multi-depot combined vehicle and crew scheduling algorithm, and uses it, in conjunction with a heuristic vehicle routing algorithm, to solve the intra-city mail distribution problem faced by Australia Post. First we describe the Australia Post mail distribution problem and outline the heuristic vehicle routing algorithm used to find vehicle routes. We present a new multi-depot combined vehicle and crew scheduling algorithm based on set covering with column generation. The paper concludes with a computational investigation examining the affect of different types of vehicle routing solutions on the vehicle and crew scheduling solution, comparing the different levels of integration possible with the new vehicle and crew scheduling algorithm and comparing the results of sequential versus simultaneous vehicle and crew scheduling, using real life data for Australia Post distribution networks.
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Poor maternal nutrition during pregnancy can alter postnatal phenotype and increase susceptibility to adult cardiovascular and metabolic diseases. However, underlying mechanisms are largely unknown. Here, we show that maternal low protein diet (LPD), fed exclusively during mouse preimplantation development, leads to offspring with increased weight from birth, sustained hypertension, and abnormal anxiety-related behavior, especially in females. These adverse outcomes were interrelated with increased perinatal weight being predictive of later adult overweight and hypertension. Embryo transfer experiments revealed that the increase in perinatal weight was induced within blastocysts responding to preimplantation LPD, independent of subsequent maternal environment during later pregnancy. We further identified the embryo-derived visceral yolk sac endoderm (VYSE) as one mediator of this response. VYSE contributes to fetal growth through endocytosis of maternal proteins, mainly via the multiligand megalin (LRP2) receptor and supply of liberated amino acids. Thus, LPD maintained throughout gestation stimulated VYSE nutrient transport capacity and megalin expression in late pregnancy, with enhanced megalin expression evident even when LPD was limited to the preimplantation period. Our results demonstrate that in a nutrient-restricted environment, the preimplantation embryo activates physiological mechanisms of developmental plasticity to stablize conceptus growth and enhance postnatal fitness. However, activation of such responses may also lead to adult excess growth and cardiovascular and behavioral diseases. © 2008 by the Society for the Study of Reproduction, Inc.
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Dixie Before Disney: 100 Years of Roadside Fun by Tim Hollis (Jackson, Miss.: University Press of Mississippi, 1999), ISBN 1-57806-117-2, 206 pages, including acknowledgements, tables, index, $25 paperback.
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A high-resolution record of radiolarian faunal changes from Site Y8 south of the Subtropical Front (STF), offshore eastern New Zealand, provides insight into the paleoceanographic history of the last 265 kyrs. Quantitative analysis of radiolarian paleotemperature indicators and radiolarian-based sea surface temperature (SST) estimates reveal distinct shifts during glacial-interglacial (G-I) climate cycles encompassing marine isotope stages (MIS) 8-1. Faunas at Site Y8 are abundant and diverse and consist of a mixture of species typical of the subantarctic, transitional and subtropical zones which is characteristic of subantarctic waters just south of the STF. During interglacials, diverse radiolarian faunas have increased numbers of warm-water taxa (not, vert, similar 15%) while cool-water taxa decrease to not, vert, similar 11% of the assemblage. Warmest climate conditions occurred during MIS 5.5 and the early Holocene Climatic Optimum (HCO) at the onset of MIS 1 where SSTs reach maxima of 12.8 and 12.9 °C, respectively. This suggests that temperatures during the HCO were comparable to the Eemian, one of the warmest interglacial intervals of the Late Quaternary. Glacials are characterized by less diverse radiolarian faunas with cool-water taxa increasing to 49% of the assemblage. Coolest climate conditions occurred in MIS 4 and 2 where SSTs are reduced to 5.4 °C and 4.3 °C, respectively. Radiolarian faunal changes and SST estimates clearly identify major water masses and oceanic fronts in the offshore eastern New Zealand area. During warmest MIS 5.5 and early MIS 1 substantial influence of northern-sourced Subtropical Surface Water (STW) is evident at Site Y8. This implies southward incursions of STW around the eastern crest of Chatham Rise with the STF displaced towards higher latitudes and spinning off eddies as far south as Campbell Plateau. Additionally, increased flow of the Southland Current (SC) might have enhanced the local occurrence of warm-water radiolarians derived from the subtropical Tasman Sea. Coolest glacials are marked by a strong inflow of cool, southern-sourced waters at Site Y8 indicating a more vigorous flow along the Subantarctic Front (SAF).
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Acknowledgements: The authors would like to thank Total E&P and BG Group for project funding and support, and the Industry Technology Facilitator for facilitating the collaborative development (grant number 3322PSD). The authors would also like to express their gratitude to the Aberdeen Formation Evaluation Society and the College of Physical Sciences at the University of Aberdeen for partial financial support. Raymi Castilla (Total E&P), Fabrizio Agosta and Cathy Hollis are also thanked for their constructive comments and suggestions to improve the standard of this manuscript as are John Still and Colin Taylor (University of Aberdeen) for technical assistance in the laboratory. Piero Gianolla is thanked for his editorial handling of the manuscript.
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Peer reviewed
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Acknowledgments The Physical Activity 4 Everyone intervention trial was funded by the New South Wales Ministry of Health through the New South Wales Health Promotion Demonstration Research Grants Scheme and conducted by Hunter New England Population Health (a unit of the Hunter New England Local Health District), in collaboration with the University of Newcastle and University of Wollongong. Infrastructure support was provided by Hunter Medical Research Institute. The research team acknowledges the importance of making research data publically available. Access to the accelerometer data from this study may be made available to external collaborators following the development of data transfer agreements. Further results arising from the study can be found at www.goodforkids.nsw.gov.au/high-schools/.
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Inscription: Verso: mother takes baby to work, Lee Morgan and infant, New York.
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Inscription: Verso: The Crescent Quartet, Cerridwen Salon, New York.
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Inscription: Verso: "Nefertiti/Deuonia Evangeline" New York.