Closure of the Challinor Centre II: An extended report on 95 individuals after 12 months of community living

As part of an institutional closure programme, 95 individuals with an intellectual disability were relocated to community-based group homes. Each individual was assessed 6 months prior to the relocation and then again after 1, 6, and 12 months of community living. Assessments involved ratings of adaptive and maladaptive behaviour, choice-making, and life circumstances. The group means comparing institution to community ratings showed improvements in adaptive functioning but no significant change in maladaptive behaviour. There were also improvements in life circumstances and increased opportunities for choice-making following relocation to the community. These outcomes suggest that relocation to the community was associated with a more active and normalised lifestyle than experienced in the institutional setting.

Industrial relations decentralisation and the growth of 12-hour shifts in Australia

In the last two decades, increasing numbers of workplaces in Australia have introduced 12-hour shifts. This increase is due, in part, to government policies aimed at promoting labour flexibility. The purpose of this paper is to examine the cover afforded by the Workplace Relations Act 1996 and other industrial relations legislation in terms of shift-workers’ health and safety. Particular reference is made to the broader social, economic and political context surrounding the introduction and use of 12-hour shifts, as it is this context that shapes the constraints and opportunities facing employers and employees in the work arrangements they choose and how they are negotiated. We conclude that the current system of regulating industrial relations in Australia is largely outcome-focused and inadequate. The bargaining process receives little regulation in terms of considering how changes could affect health and safety in the workplace or how changes might affect individual workers. As a result, the increased introduction of unsafe shiftworking arrangements is a worrying, and likely, prospect.

Acquired central diabetes insipidus in children: A 12 year Brisbane experience

Objective: To study the clinical, endocrine and radiological features and progress of children presenting with acquired diabetes insipidus (CDI). Methodology: Chart review of children presenting because of CDI to Brisbane paediatric endocrine clinics between 1987 and 1999. Results: Thirty-nine children (female/male ratio 21/18) aged 0.1-15.4 years (mean age 6.7 years) were identified. Aetiologies were head trauma or familial in eight cases (20.5%) each, central nervous system (CNS) tumours in five cases (12.8%), CNS malformations in four cases (10.2%), histiocytosis in three cases (7%) and hypoxia and infection in two cases (5.1%) each. Seven cases (17.9%) remain undiagnosed. Of the 32 (82%) cases with isolated anti-diuretic hormone deficiency at presentation, 24 cases (61.5%) experienced no further endocrine deficit. Additional endocrine deficits occurred mainly in the tumour or undiagnosed groups. On follow-up brain magnetic resonance imaging (MRI) scans in the seven undiagnosed cases, six patients bad mild or no change and one patient had marked improvement of MRI findings. These changes occurred 10-48 months (mean 18 months) after presentation. Conclusions: Children without an aetiological diagnosis for the uncommon condition of acquired CDI require careful follow-up. More intensive investigation at presentation (e.g. estimation of cerebrospinal fluid human chorionic gonadotrophin) promises to lessen the number of such cases. Pituitary stalk biopsies should be reserved for those patients with progressive MRI changes. If these changes do not occur early, our experience suggests that follow-up MRI scans may need to be performed only yearly.

The rights to a deceased's body and body parts : in the matter of Gray (2000) QSC 390 (12/10/2000).

Decision In the Matter of Gray highlights complications that advancing medical technology causes to the law - case concerns the issue of removal of semen from a deceased man - how the courts deal with matters concerning medical technology in the absence of specific legislation or established case law - legal and moral questions raised by the case.

Oral administration of a 12% sucrose solution did not decrease behavioural indicators of distress in piglets undergoing tail docking, teeth clipping and ear notching

Sucrose has been shown to attenuate the behavioural response to painful procedures in human infants undergoing circumcision or blood collection via heelstick. Sucrose has also been found to have a behaviour-modifying effect in neonatal rats exposed to a hot plate. The effect was abolished in neonatal rats by injection of the opioid antagonist naltrexone, suggesting that it was mediated by endogenous opioids. In this experiment, the behaviour of 571 newborn Large White x Landrace hybrid piglets in a specific-pathogen-free piggery of the University of Queensland was recorded during and after the routine management practices of tail docking, ear notching and teeth clipping. Piglets were randomly assigned to receive 1.0 ml of a 12% sucrose solution (treatment group) or a placebo (1.0 ml of air) administered via syringe in the mouth, 60 s before commencement of one of the management procedures. Behaviours were recorded at the time of the procedure, and then 2 min after completion of the procedure. Piglets that received the sucrose solution did not behave significantly differently from piglets receiving the placebo. Regardless of whether sucrose or placebo was administered, piglets undergoing the routine management procedures showed significantly greater behavioural responses than piglets undergoing no procedure. It was concluded that under commercial conditions, a 12% sucrose solution administered I min prior to surgery was not effective in decreasing the behavioural indicators of distress in piglets undergoing routine management procedures, Further research into methods of minimising distress caused to piglets by these procedures is recommended.

Sertoli-Leydig Cell Tumor of the Ovary, a Rare Cause of Precocious Puberty in a 12-Month-Old Infant

We report a 12-month-old infant who presented with a 4-month history of isosexual precocious puberty secondary to an estrogenizing Sertoli-Leydig cell tumor of the ovary. Total serum immunoreactive inhibin and subunits A and B were markedly elevated before surgical resection and subsequently decreased 7 wk later into the normal prepubertal range. Twenty weeks following surgical removal, the patient presented again with central precocious puberty; inhibin B levels were raised on this occasion, a luteinizing releasing hormone stimulation test confirmed central precocious puberty. This is the youngest reported occurrence of this rare sex cord stromal neoplasm. The prognosis of this extremely rare tumor presenting at this early juvenile stage is uncertain. This report illustrates the usefulness of serum inhibin as a tumor marker during therapeutic suppression with leuprorelin acetate for central precocious puberty. Analysis of genomic and tumor DNA revealed a normal nucleotide sequence for the LH receptor and the G{alpha}s gene. To understand the molecular pathogenesis of this tumor we analyzed mRNA levels for the inhibin A and B subunits, FSH receptor, LH receptor aromatase, steroidogenic factor-1 and the ER ß genes. Molecular characterization reveals the presence of genes specific for granulosa and Leydig cells; the relative expression of these genes, in addition to its histologic characteristics, suggests that this tumor may result from a dysdifferentiation of a primordial follicle.

More on exact bicoverings of 12 points

The minimum number of incomplete blocks required to cover, exactly lambda times, all t-element subsets from a set V of cardinality v (v > t) is denoted by y(lambda, t; v). The value of g(2, 2; v) is known for v = 3, 4,..., 11. It was previously known that 14 less than or equal to g(2, 2; 12) less than or equal to 16. We prove that g(2, 2; 12) greater than or equal to 15.

Centile reference for total energy expenditure in infants from 1 to 12 months

Background: A knowledge of energy expenditure in infancy is required for the estimation of recommended daily amounts of food energy, for designing artificial infant feeds, and as a reference standard for studies of energy metabolism in disease states. Objectives: The objectives of this study were to construct centile reference charts for total energy expenditure (TEE) in infants across the first year of life. Methods: Repeated measures of TEE using the doubly labeled water technique were made in 162 infants at 1.5, 3, 6, 9 and 12 months. In total, 322 TEE measurements were obtained. The LMS method with maximum penalized likelihood was used to construct the centile reference charts. Centiles were constructed for TEE expressed as MJ/day and also expressed relative to body weight (BW) and fat-free mass (FFM). Results: TEE increased with age and was 1.40,1.86, 2.64, 3.07 and 3.65 MJ/day at 1.5, 3, 6, 9 and 12 months, respectively. The standard deviations were 0.43, 0.47, 0.52, 0.66 and 0.88, respectively. TEE in MJ/kg increased from 0.29 to 0.36 and in MJ/day/kg FFM from 0.36 to 0.48. Conclusions: We have presented centile reference charts for TEE expressed as MJ/day and expressed relative to BW and FFM in infants across the first year of life. There was a wide variation or biological scatter in TEE values seen at all ages. We suggest that these centile charts may be used to assess and possibly quantify abnormal energy metabolism in disease states in infants.

A????es premiadas no 12?? Concurso Inova????o na Gest??o P??blica Federal

Nesta publica????o, referente ao 12?? Concurso Inova????o na Gest??o P??blica Federal, o leitor encontrar?? iniciativas inovadoras nas seguintes ??reas: arranjos institucionais para coordena????o e/ou implementa????o de pol??ticas p??blicas; atendimento ao usu??rio; avalia????o e monitoramento de pol??ticas p??blicas; gest??o da informa????o; melhoria dos processos de trabalho

Texto para discuss??o 12: a moderniza????o do Estado: as li????es de uma experi??ncia

Falar da moderniza????o do Estado n??o ?? f??cil atualmente, t??o numerosos s??o os excelentes especialistas que, ao longo dos ??ltimos anos, dedicaram-se a este tema e produziram relat??rios n??o menos excelentes. Com efeito, se h?? um campo que tem sido regularmente classificado como uma prioridade governamental ?? exatamente este.

M??dulo 12 - julgamento e encerramento da licita????o: curso legisla????o aplicada ?? log??stica de suprimentos Lei 8.666/93, preg??o e registro de pre??os

Este documento trata de: aspectos conceituais da lei: finalidade, import??ncia e hierarquia da lei.; no????es gerais da lei de licita????es - Lei n?? 8.666/93; tipos de licita????o:menor pre??o, melhor t??cnica, t??cnica e pre??o e maior lance ou oferta; modalidades de licita????o: concorr??ncia, tomada de pre??os, convite, concurso e leil??o; exce????es ?? obrigatoriedade de licita????o: dispensa e inexigibilidade; regime de execu????o indireta; comiss??o de licita????o; etapas do processo licitat??rio: edital, procedimentos/documentos do certame, registro cadastral, habilita????o dos interessados, julgamento e encerramento; preg??o; registro de pre??os

Disciplina 4.12: controle e avalia????o da execu????o or??ament??ria e financeira

Ciclo do gasto p??blico; ciclo de gest??o dos recursos p??blicos; sistemas de administra????o p??blica; planejamento: conceito iniciais; processo de planejamento;vantagens do planejamento; or??amento p??blico: conceito; o or??amento e as fun????es do estado; fun????es do or??amento p??blico; instumentos e recursos utilizados pelo governo para intervir na economia; princ??pios or??ament??rios; inter-rela????o do planejamento/or??amento na Constitui????o de 1988; Lei de Responsabilidade Fiscal; receita p??blica: conceito; conceito de receita p??blica origin??ria; conceito de receita derivada; classifica????o da receita or??ament??ria; receita extra-or??ament??ria; est??gios da receita; classifica????o da receita quanto a origem e a fonte dos recursos; receitas vinculadas; despesa p??blica: conceito; Classifica????o da despesa: institucional ou por ??rg??os, por fun????es, classifica????o econ??mica, classifica????o por objeto de gasto; execu????o do or??amento; objetivos da programa????o or??ament??ria e financeira; enfoque fiscal dos or??amentos; Necessidade de Financiamento do Governo Central; processo de elabora????o dos limites or??ament??rios; acompanhamento da execu????o; import??ncias das metas fiscais; detalhamento do cr??dito or??ament??rio; cr??ditos adicionais; est??gios da despesas p??blica; descentraliza????o de cr??ditos; administra????o financeira: exerc??cio financeiro; descentraliza????o de recursos financeiros; libera????o de recursos; elabora????o da programa????o financeira; formas de execu????o da despesa p??blica; princ??pios da administra????o p??blica; conceito de licita????o; princ??pios da licita????o; modalidades de licita????o; dispensa e inexigibilidade; transfer??ncias volunt??rias : da formaliza????o; plano de trabalho; restos a pagar; despesas de exerc??cios anteriores; di??rias; suprimento de fundos; modelo brasileiro de controle or??ament??rio

Novos desafios para a capacita????o de lideran??a de alto n??vel na gest??o p??blica e governan??a em um mundo globalizante

Este artigo aborda as mudan??as econ??micas, sociais, ambientais e comportamentais que est??o ocorrendo no planeta, visando a estabelecer um contexto que sirva de base para o tipo de capacita????o mais adequado para os n??veis gerenciais de governo. A partir de tr??s fatores interdependentes ??? globaliza????o, difus??o da democracia e impactos na governan??a ??? ?? proposta uma estrutura de capacita????o, focalizando 12 diferentes ??reas.

Resolu????o n?? 12, de 31 de outubro de 2014: estabelece a Pol??tica de Seguran??a da Informa????o e Comunica????es - PoSIC no ??mbito da ENAP

A Escola Nacional de Administra????o P??blica (Enap) publicou, no dia 31 de outubro de 2014, a Resolu????o n?? 12, que estabelece a Pol??tica de Seguran??a da Informa????o e Comunica????es (PoSIC). A PoSIC institui diretrizes estrat??gicas, responsabilidades e compet??ncias, visando assegurar a disponibilidade, integridade, confidencialidade e autenticidade das informa????es produzidas ou custodiadas pela Enap, de modo a preservar os seus ativos e sua imagem institucional. A Pol??tica trata do uso e compartilhamento do conte??do de dados, informa????es e documentos no ??mbito da Enap, em todo o seu ciclo de vida - cria????o, manuseio, divulga????o, armazenamento, transporte e descarte. O objetivo ?? garantir a continuidade de seus processos cr??ticos, em conformidade com a legisla????o vigente, normas pertinentes, requisitos regulamentares e contratuais, valores ??ticos e as melhores pr??ticas de seguran??a da informa????o e comunica????es.