Precision medicine in patients with allergic diseases: Airway diseases and atopic dermatitis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology

In this consensus document we summarize the current knowledge on major asthma, rhinitis, and atopic dermatitis endotypes under the auspices of the PRACTALL collaboration platform. PRACTALL is an initiative of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology aiming to harmonize the European and American approaches to best allergy practice and science. Precision medicine is of broad relevance for the management of asthma, rhinitis, and atopic dermatitis in the context of a better selection of treatment responders, risk prediction, and design of disease-modifying strategies. Progress has been made in profiling the type 2 immune response-driven asthma. The endotype driven approach for non-type 2 immune response asthma, rhinitis, and atopic dermatitis is lagging behind. Validation and qualification of biomarkers are needed to facilitate their translation into pathway-specific diagnostic tests. Wide consensus between academia, governmental regulators, and industry for further development and application of precision medicine in management of allergic diseases is of utmost importance. Improved knowledge of disease pathogenesis together with defining validated and qualified biomarkers are key approaches to precision medicine.

De Arnobii stvdiis Latinis.

Vita.

Dei diplomati italiani e delle relazione diplomatiche dell'Italia dal 1260 al 1550 /

Mode of access: Internet.

Dizionario di mitologia; ossia, Dizionario delle favole degli antichi ...

Mode of access: Internet.

Studien zu Arnobius : Vorgetragen am 2. Mai 1908 /

Mode of access: Internet.

Arnobii Adversvs nationes libri VII.

Includes bibliographical references and index.

Rivista delle varie lezioni della Divina commedia : sinora avvisate col catalogo delle più importanti edizioni /

Mode of access: Internet.

Sieben bücher wider die heiden,

Mode of access: Internet.

Parnaso classico italiano : contenente Dante, Petrarca, Ariosto e Tasso.

Includes indexes.

Statistica della città e provincia di Padova : dettata /

Mode of access: Internet.

Arnobii Adversvs nationes libri VII : ex nova codicus Parisini collatione recensuit notas omnium editorium selectas adiecit perpetuis commentariis illustravit /

Mode of access: Internet.

Relazioni delle memorie lette nell' I.R. Accademia di scienze, lettere ed arti in Padova negli anni MDCCCXL-MDCCCXLI.

Port. of Gralilei.

Atmospheric Poaceae pollen frequencies and associations with meteorological parameters in Brisbane, Australia: a 5-year record, 1994-1999

Grass pollen is an important risk factor for allergic rhinitis and asthma in Australia and is the most prevalent pollen component of the aerospora of Brisbane, accounting for 71.6% of the annual airborne pollen load. A 5-year (June 1994-May 1999) monitoring program shows the grass pollen season to occur during the summer and autumn months (December-April), however the timing of onset and intensity of the season vary from year to year. During the pollen season, Poaceae counts exceeding 30 grains m(-3) were recorded on 244 days and coincided with maximum temperatures of 28.1 +/- 2.0degreesC. In this study, statistical associations between atmospheric grass pollen loads and several weather parameters, including maximum temperature, minimum temperature and precipitation, were investigated. Spearman's correlation analysis demonstrated that daily grass pollen counts were positively associated (P < 0.0001) with maximum and minimum temperature during each sampling year. Precipitation, although considered a less important daily factor (P < 0.05), was observed to remove pollen grains from the atmosphere during significant periods of rainfall. This study provides the first insight into the influence of meteorological variables, in particular temperature, on atmospheric Poaceae pollen counts in Brisbane. An awareness of these associations is critical for the prevention and management of allergy and asthma for atopic individuals within this region.