The longitudinal course of gross motor activity in schizophrenia - within and between episodes

Schizophrenia is associated with heterogeneous course of positive and negative symptoms. In addition, reduced motor activity as measured by wrist actigraphy has been reported. However, longitudinal studies of spontaneous motor activity are missing. We aimed to explore whether activity levels were stable within and between psychotic episodes. Furthermore, we investigated the association with the course of negative symptoms. In 45 medicated patients, we investigated motor behavior within a psychotic episode. In addition, we followed 18 medicated patients across 2 episodes. Wrist actigraphy and psychopathological ratings were applied. Within an episode symptoms changed but activity levels did not vary systematically. Activity at baseline predicted the course of negative symptoms. Between two episodes activity recordings were much more stable. Again, activity at the index episode predicted the outcome of negative symptoms. In sum, spontaneous motor activity shares trait and state characteristics, the latter are associated with negative symptom course. Actigraphy may therefore become an important ambulatory instrument to monitor negative symptoms and treatment outcome in schizophrenia.

Wie sie gross und reich wurden : Lebensbilder erfolgreicher Männer

von Morus [[Elektronische Ressource]]

"Gross"- und "Klein"-Kolonisation

Selig Eugen Soskin

"Gross"- und "Klein"-Kolonisation

Selig Eugen Soskin

Dr. Heinrich Gross [Illustration] : (Porträt)

Scan von Monochrom-Mikroform

Glossen zu Gross' Gallia Judaica

Abraham Epstein

Fritz Gross

Georg Merkel

Systematisches Verzeichnis der Lepidopteren von Gross Pallubin und Umgegend im Kreise Berent

von Leop. Eichmann

Ferdinand Gross, Brustbild

Signatur des Originals: S 36/F00599

Franz Gross als Ollendorf, Rollenbild, in: Karl Millöcker: Der Bettelstudent

Signatur des Originals: S 36/F04255

Carl Gross, Brustbild

Signatur des Originals: S 36/F04256

Ferdinand Gross, Kniestück

Signatur des Originals: S 36/F08700

Jenny Gross, Rollenbild, Brustbild

Signatur des Originals: S 36/F08701

Jenny Gross als Marie Theresia, Rollenbild, Brustbild

Signatur des Originals: S 36/F08702