Offshore coho salmon populations near the Pacific Northwest and large-scale atmospheric events

EXTRACT (SEE PDF FOR FULL ABSTRACT): Catch of coho salmon off the coast of Washington and Oregon since 1925 appears to be related to large-scale events in the atmosphere, which in turn affect ocean currents and coastal upwelling intensities in the northeastern Pacific. At least two time scales of variations can be identified. The first is that of the El Nino/Southern Oscillation phenomenon giving rise to an irregular cycle of between 3 to 7 years. ... The second time scale of variation seems to have a periodicity of about 20 years, although this is based on a limited dataset. ... This paper endeavors to describe how, if real, these atmospheric/oceanic effects are integrated and might affect the salmon catch. The possibility must also be considered that the atmospheric events are symbiotically related to the oceanic events and, further, that both may be enmeshed in even longer-term variability of climate.

Chronological records of climate-related events and societal consequences [abstract]

EXTRACT (SEE PDF FOR FULL ABSTRACT): A chronology of documented regional and global warm and cold event records is collated along with documented ecosystem response records and health threat/sequellae records for the historical period. Patterns of societal response to cold periods punctuated by warm periods have been associated with considerable human health impacts, stimulated by blooms in disease vectors such as rodents and insects.

Population phylogenomic analysis of mitochondrial DNA in wild boars and domestic pigs revealed multiple domestication events in East Asia

Background: Previously reported evidence indicates that pigs were independently domesticated in multiple places throughout the world. However, a detailed picture of the origin and dispersal of domestic pigs in East Asia has not yet been reported. Results:

Reinforcement-related neurons in the primate basal forebrain respond to the learned significance of task events rather than to the hedonic attributes of reward

The objective of this study was to determine if the responses of basal forebrain neurons are related to the cognitive processes necessary for the performance of behavioural tasks, or to the hedonic attributes of the reinforcers delivered to the monkey as

The Bayesian view of extreme events

The Bayesian perspective of designing for the consequences of hazard is discussed. Structural engineers should be educated in Bayesian theory and its underlying philosophy, and about the centrality to the prediction problem of the predictive distribution. The primary contribution that Bayesianism can make to the debate about extreme possibilities is its clarification of the language of and thinking about risk. Frequentist methodologies are the wrong approach to the decisions that engineers need to make, decisions that involve assessments of abstract future possibilities based on incomplete and abstract information.

Neural activity associated with the passive prediction of ambiguity and risk for aversive events.

In economic decision making, outcomes are described in terms of risk (uncertain outcomes with certain probabilities) and ambiguity (uncertain outcomes with uncertain probabilities). Humans are more averse to ambiguity than to risk, with a distinct neural system suggested as mediating this effect. However, there has been no clear disambiguation of activity related to decisions themselves from perceptual processing of ambiguity. In a functional magnetic resonance imaging (fMRI) experiment, we contrasted ambiguity, defined as a lack of information about outcome probabilities, to risk, where outcome probabilities are known, or ignorance, where outcomes are completely unknown and unknowable. We modified previously learned pavlovian CS+ stimuli such that they became an ambiguous cue and contrasted evoked brain activity both with an unmodified predictive CS+ (risky cue), and a cue that conveyed no information about outcome probabilities (ignorance cue). Compared with risk, ambiguous cues elicited activity in posterior inferior frontal gyrus and posterior parietal cortex during outcome anticipation. Furthermore, a similar set of regions was activated when ambiguous cues were compared with ignorance cues. Thus, regions previously shown to be engaged by decisions about ambiguous rewarding outcomes are also engaged by ambiguous outcome prediction in the context of aversive outcomes. Moreover, activation in these regions was seen even when no actual decision is made. Our findings suggest that these regions subserve a general function of contextual analysis when search for hidden information during outcome anticipation is both necessary and meaningful.

Towards manipulation of post-biosynthetic events in secondary metabolism of plant cell cultures

Plant cell cultures have been suggested as a feasible technology for the production of a myriad of plant-derived metabolites. However, commercial application of plant cell culture has met limited success with only a handful of metabolites produced at the pilot- and commercial-scales. To improve the production of secondary metabolites in plant cell cultures, efforts have been devoted predominantly to the optimization of biosynthetic pathways by both process and genetic engineering approaches. Given that secondary metabolism includes-the synthesis. metabolism and catabolism of endogenous compounds by the specialized proteins, this review intends to draw attention to the manipulation and optimization of post-biosynthetic events that follow the formation of core metabolite structures in biosynthetic pathways. These post-biosynthetic events-the chemical and enzymatic modifications, transport, storage/secretion and catabolism/degradation have been largely unexplored in the past. Potential areas are identified where further research is needed to answer fundamental questions that have implications for advanced bioprocess design. Anthocyanin production by plant cell cultures is used as a case study for this discussion, as it presents a good example of compounds for which there are extensive research publications but still no commercial bioprocess. It is perceived that research on post-biosynthetic processes may lead to future opportunities for significant advances in commercial plant cell cultures. (C) 2002 Elsevier Science Inc. All rights reserved.