Terapia do diabetes mellitus em cães

Diabetes Mellitus is caracterized by a disturbance on endocrine pâncreas with reduction in serum levels of insulin. The deficiency or absence of insulin promotes alterations in the metabolism of carbohydrates, lipidis and proteins. The most common clinical signs of disease are polyuria, polydipsia, polyphagia and loses of weight. The diagnosis is made based on clinical symptoms, with laboratory confirmation through persistent hyperglycemia on fasting and glycosuria. Treatment includes insulin therapy, diet, exercise and oral hypoglycemic agents in an attempt to reverse the catabolic effects associated with deficiency or antagonism of insulin and restore normal homeostasis of the metabolism of proteins, lipids and carbohydrates

Doenças osteoarticulares em pequenos animais

Osteoarticular diseases are very frequent in small animals, especially dogs. Osteoarthritis is the most common degenerative arthropathy in cats and dogs. It is one of the most important skeletal disease in small animals and it is divided into two broad classes: secondary and genetics. The secondary is originated from situations that can cause joint instability like as trauma, ligament problems and obesity among others. The gene for osteoarthritis comes from hereditary problems such as hip dysplasia, elbow dysplasia and other diseases that can cause articular instability. The hereditary osteoarticular diseases are important only because they can result in the osteoarthritis. It is important to prevent the joint instability and consequently the clinical signs that affect the quality of life of the animals. The most common clinical signs are intermittent claudication, a decrease in performance, reluctance to jump and climb ladders among others. To prevent the clinical signs or mitigate them, the treatments need to be focused on pain control and especially restoration of the affected joint. The treatments most used are the medical and surgery. Anti-inflammatory and analgesics are used in large scale for pain control and to inhibit inflammatory mediators. Furthermore, medical treatment includes weight reduction, physiotherapy and proper nutrition along with anti-inflammatory and analgesics. Surgical treatments are indicated if there is an inadequate response to medical treatment. Physiotherapy is often used in conjunction with other treatments. Besides the reduction of weight is essential and obesity is unacceptable. Cats also suffer from osteoarthritis, but the diagnosis is rarer than in dogs. Usually the cat’s owners relate the reluctance to jump and drop in performance with senility, and when the disease is diagnosed is already in... (Complete abstract click electronic access below)

Insuficiência renal crônica em cães

The kidneys, for his anatomical and functional characteristics, are sensitive to affections that take the liberation of renal toxins or the blood supply, causing irreversible injuries to his renoparenchymal tissue that is substituted by fibrous tissue. Even after the resolution of the basic cause, there will be the loss of a significant number of his functional unity, renal adaptations will take place in the attempt of maintaining the renal function. These adaptations produce additional injuries, perpetuating to loss of renoparenchymal tissue and the reduction of the renal function. The renal insufficiency (IR) takes place after the loss of 3/4 of the number of his functional unities. Before the progression to the phase of IR, the animal shows up practically without symptoms, but for the gradual increase of the urinary and of the ingestion of water. The reduction of the degree of renal function leads to alterations system compensatory for the accumulation of substances that would suffer renal excretion. The progression of IR leads to the phase of the syndrome urêmica. In this phase the animal presents innumerable clinical signs that can take it to the death. The treatment is symptomatic and dietetic, but depending on the phase not much efficient. Because of being progressive and insidious, the IRC demands the preparation of campaigns and programs of explanation for the veterinary doctors who aim for the consciousness and/or sensibility of the owners to carry out periodic examinations of selection that precociously detect the renal dysfunction. The diagnosis in the beginning IR enables the efficiency of the treatment in stop or slowing his progression, extending the time and quality of life of the patient

Pressão arterial em cães: uma revisão

The evaluation of blood pressure is an essential tool for veterinarian clinical practice and for monitoring anesthetized patients or patients in intensive care, because of its usefulness in diagnostics, treatment and monitoring of several diseases. Apart from the pathological factor, the blood pressure also suffers the influence of different variables, such as age, breed, gender, temperament (anxiety and stress especially during the treatment, “white coat syndrome”), disease state, physical activity and, with lower intensity, animal’s diet. One of the main indications of the evaluation of blood pressure is the observation of clinical changes resulting from hypertension in animals, which one is characterized by lesions in the nervous and cardiovascular systems, kidneys and eyes. Not least important, the evaluation of blood pressure is also essential in hypotensive states, which represent an imminent risk of death. The techniques used in measuring blood pressure correspond to invasive forms (direct) or non invasive (indirect), whose correlation has been the subject of study and improvement within the small animal clinic. Thus, the purpose of this review is emphasize the importance of measuring blood pressure within the veterinary clinic routine, studying the influence of variables associated or not with elevated blood pressure, comparing the different methods used to obtain the blood pressure

Pênfigo Foliáceo em cães

Pemphigus complex in animals is considered rare, but not so when compared with the occurrence of other autoimmune diseases. Pemphigus Foliaceus in dogs is the most common varieties of pemphigus and is characterized clinically by intraepidermal pustules, starting on the face and ears, pads, groin, and may become multifocal or generalized in six months. As the pustules are very fragile, the lesions usually found are secondary, which may range from dry to collarettes epidermal crusting, and nasal depigmentation. The diagnosis is difficult because presents sintomatology similar to other diseases and laboratory diagnosis more precise through the histopathological examination of pustules integrate (biopsy), which are rarely found. The treatment, although of the individual treatment regimen, is based on treating opportunistic diseases and immunosuppressing the animal in order to decrease the production of autoantibodies. The drugs of choice depend on the clinical presentation, however is usually oral prednisone and azathioprine in the dog and combined immunosuppressive therapy. Should make use daily until the disease is inactive and gradually decrease the dose until have the minimum effective dose, preferably on alternate days for the remission of the disease. Prognosis of pemphigus varies according to disease stage and treatment established. Pemphigus foliaceus is less serious nonetheless might be fatal without treatment

Alterações hepáticas em cães intoxicados experimentalmente por sementes de Crotalaria spectabilis

Pós-graduação em Medicina Veterinária - FCAV

Mensuração do volume atrial esquerdo pelo método biplanar de Simpson em cães portadores da doença mixomatosa da válvula mitral

Pós-graduação em Medicina Veterinária - FCAV

Células T reguladoras em sangue periférico de cães portadores de mastocitoma cutâneo

Pós-graduação em Medicina Veterinária - FCAV

Identificação de DNA de Leishmania sp. no encéfalo de cães com Leishmaniose visceral

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Parâmetros clínicos e laboratoriais relacionados ao prognóstico em cães com gastroenterite hospitalizados

Pós-graduação em Cirurgia Veterinária - FCAV

Prostaglandina E2 em cães portadores de linfoma multicêntrico submetidos ao protocolo quimioterápico de Madison-Wisconsin associado ou não a um inibidor de COX-2

Pós-graduação em Medicina Veterinária - FCAV

Compartimentalização da resposta imune e sua relação com o perfil de citocinas em diferentes órgãos de cães leishmaniose visceral

Pós-graduação em Medicina Veterinária - FCAV

Quantificação imunofenotípica de células T reguladoras em cães acometidos por linfoma multicêntrico submetidos ao protocolo quimioterápico chop associado ou não a um firocoxib

Pós-graduação em Medicina Veterinária - FCAV

Fator de crescimento do endotélio vascular e do transportador de glicose 1 em cães com ceratose actínica e carcinoma de células escamosas

Pós-graduação em Medicina Veterinária - FCAV

Classificação morfológica e imunostoquímica em microarranjo de tecido (TMA) de linfomas não-Hodgkin em cães conforme os critérios da Histological Classification od Hematopoietic Tumors of Domestic Animals (WHO)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)