Treatment of adriamycin-induced nephropathy with erythropoietin and G-CSF

Background: Granulocyte colony-stimulating factor (G-CSF) and Erythropoietin (EPO) are known to stimulate the growth and differentiation of progenitor cells to prevent acute renal injury. This study aimed to assess the use of growth factors to mobilize stem cell in a mouse model of adriamycin-induced chronic kidney disease. Methods: All animals were injected with adriamycin for kidney injury and allocated into three treatment groups (G-CSF, EPO and G-CSF + EPO), and a control group (adriamycin alone). Results: Number of atrophic sites, glomerulosclerosis rate and interstitial fibrosis severity score were assessed in all groups. In all treatment groups, histologic parameters did not significantly differ, but were lower than in the control group (P<.001). Scal and CD34 expressions among treatment groups showed no statistically significant difference, but were higher than in the control group (P<.0001). CD105 expression was higher in EPO and G+EPO as compared to G-CSF and the control group (P<.0001), with no statistically significant difference between the latter two groups (P = NS). Conclusion: G-CSF and EPO had a histologic protective effect, while treatment with EPO + G-CSF had no additive effects in a model of adriamycin-induced chronic kidney disease. © 2013 Societá Italiana di Nefrologia.

Quasi-homologous spherically symmetric branes and their symmetry breaking

We revisit the dynamical system-based approach of spherically symmetric vacuum braneworlds, pointing out and studying the existence of a transcritical bifurcation as the dark pressure parameter changes its sign, we analyze some consequences of not discard the brane cosmological constant. For instance, it is noteworthy that the existence of an isothermal state equation between the dark fluid parameters cannot be obtained via the requirement of a quasi-homologous symmetry of the vacuum. © 2013 Springer-Verlag Berlin Heidelberg and Società Italiana di Fisica.

Consórcio de exportação e a internacionalização das pequenas e médias empresas segundo a experiência italiana: um modelo para o Brasil. -

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Memórias Póstumas de Brás Cubas e a Consciência de Zeno: representações históricas das sociedades brasileira e italiana

Pós-graduação em Letras - IBILCE

Os territórios da imigração alemã e italiana no Rio Grande do Sul

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Arte e cultura, política e filosofia: a crítica do contemporâneo nas crônicas de Umberto Eco

Pós-graduação em Letras - FCLAS

Percurso para a elaboração de um teste para avaliação da compreensão em língua italiana de (futuros) professores

Pós-graduação em Estudos Linguísticos - IBILCE

O processo de securitização e despolitização do imigrante: a política migratória italiana nos anos 1990-2000

Pós-graduação em Relações Internacionais (UNESP - UNICAMP - PUC-SP) - FFC

Ciência e tecnologia na literatura italiana de Dante a Leopardi

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

O olhar feminino na narrativa italiana do século XX

This essay will describe the italian women who dedicated their novels and tales in the nineth Century to the people and the brazilian culture. I intend to remark the female point of view of these writers, very different of the others writers which novels and tales described only the exotic and pitoresc. Keywords Italian writers; Brazilian characters; female point of view; Italian novels of the 20th century.

Passageiros de terceira classe: o transporte de emigrantes na história econômica da Navigazione Generale Italiana

From the 1860s, the Italian emigration reached many entily, becoming on national problem and a source of revenue for shipping companies operating in the Atlantic. In Italy, the resources were fundamental in financing the replacement of the old sailboats by more modern steamers. Established in 1881, the Navigazione Generale Italiana (NGI) had not scoped to carry passengers. It acted in trade of goods conjugated with postal services widely subsidized by the state. By incorporating that transported immigrants, in a concentration process that would transform it in the largest shipping company in Italy, the NGI opened the thriving business of emigration to the Americas. Based on reports and Balance Exercises Financial of the company between the years 1881 and 1915, papers relating to merchant shipping and emigration legislation (laws of 1888 and 1901), this paper aims to present some results of research on the importance trafficking of Italian emigrants Navigazione Generale Italiana for marking the specialization process of its fleet this kind of service.

Imprensa italiana em São Paulo e o fascismo: o Fanfulla (1921-1942)

This article intends to verify the Fanfulla's action in the dynamic of the political propaganda, as well as the cultural exchanges established with the fascism during 1922-1924. The leading question is insert on the political culture studies concerned with the significance of the fascism spread among the Italian immigrants and his descendants located on the Sao Paulo State. It unfold in others questions: the reason of the Mussolini government pledge to publish those ideas, the themes approached in this propaganda, the reactions it rise, as well on the Italian community, the Brazilian government and political movements. On this issue is included the position of the Brazilian government, on the Brazilian diplomacy or in the repressive agencies toward fascist Italy and the supporters of the fascism. The choice of the newspaper Fanfulla is justified for its position in the historiography, considered the most expressive source for this study, due its longevity, relations with the fascist regime and diffusion on Sao Paulo State.

Neutron-proton mass difference in nuclei in a relativistic harmonic quark model

The nuclear dependence of the neutron-proton mass difference is examined in a relativistic harmonic quark model with the assumption of a swelling of the individual nucleon originated by a decrease of the spring constant inside the nuclear medium. A decrease of the neutron-proton mass difference is obtained which is reasonably small and in the right direction to cope with the Nollen-Schiffer anomaly in mirror nuclei. © 1992 Società Italiana di Fisica.

Spin coherent states in NMR quadrupolar system: experimental and theoretical applications

Working with nuclear magnetic resonance (NMR) in quadrupolar spin systems, in this paper we transfer the concept of atomic coherent state to the nuclear spin context, where it is referred to as pseudonuclear spin coherent state (pseudo-NSCS). Experimentally, we discuss the initialization of the pseudo- NSCSs and also their quantum control, implemented by polar and azimuthal rotations. Theoretically, we compute the geometric phases acquired by an initial pseudo-NSCS on undergoing three distinct cyclic evolutions: (i) the free evolution of the NMR quadrupolar system and, by analogy with the evolution of the NMR quadrupolar system, that of (ii) single-mode and (iii) two-mode Bose-Einstein Condensate like system. By means of these analogies, we derive, through spin angular momentum operators, results equivalent to those presented in the literature for orbital angular momentum operators. The pseudo-NSCS description is a starting point to introduce the spin squeezed state and quantum metrology into nuclear spin systems of liquid crystal or solid matter.