[La vie du Cardinal de Bérulle].

Mode of access: Internet.

Die englische Legation des Cardinals Guido Fulcodi, des spaeteren P. Clemens IV.

Thesis (doctoral)--Universitat Breslau.

History of the great civil war, 1642-1649.

Mode of access: Internet.

English dramatic companies, 1558-1642.

Bibliographical footnotes.

Regulation of trade in drugs: hearings, Ninety-first Congress, second session, on S. 1575, to regulate trade in drugs and devices by prohibiting the dispensing of drugs or devices by medical practitioners and their participation in profits from the dispensing of such products, except under certain circumstances, and for other purposes, June 16 and 17, 1970.

"Serial no. 91-81."

A history of Tasmania, from its discovery in 1642 to the present time.

Mode of access: Internet.

Reading Pitscottie's Cronicles: a case study on the history of literacy in Scotland, 1575-1814

This thesis addresses a range of research questions regarding literacy in early modern Scotland. Using the early modern manuscripts and printed editions of Robert Lindsay of Pitscottie’s late sixteenth-century 'Cronicles of Scotland' as a case study on literacy history, this thesis poses the complementary questions of how and why early modern Scottish reading communities were encountering Pitscottie’s 'Cronicles', and how features of the material page can be interpreted as indicators of contemporary literacy practices. The answers to these questions then provide the basis for the thesis to ask broader socio-cultural and theoretical questions regarding the overall literacy environment in Scotland between 1575 and 1814, and how theorists conceptualise the history of literacy. Positioned within the theoretical groundings of historical pragmatics and ‘new philology’ – and the related approach of pragmaphilology – this thesis returns to the earlier philological practice of close textual analysis, and engages with the theoretical concept of mouvance, in order to analyse how the changing ‘form’ of Pitscottie’s 'Cronicles', as it was reproduced in manuscript and print throughout the early modern period, indicates its changing ‘function’. More specifically, it suggests that the punctuation practices and paratextual features of individual witnesses of the text function to aid the highly-nuanced reading practices and purposes of the discrete reading communities for which they were produced. This thesis includes extensive descriptive material which presents previously unrecorded data regarding twenty manuscripts and printed witnesses of Pitscottie’s 'Cronicles', contributing to a gap in Scotland’s literary/historiographical canon. It then analyses this material using a transferable methodological framework which combines the quantitative analysis of micro-data with qualitative analysis of this data within its socio-cultural context, in order to conduct diachronic comparative analysis of copy-specific information. The principal findings of this thesis suggest that Pitscottie’s 'Cronicles' were being read for a combination of devotional and didactic purposes, and that multiple reading communities, employing highly nuanced reading practices, were encountering the text near-contemporaneously. This thesis further suggests that early modern literacy practices, and the specific reading communities which employ them, should be described as existing within a spectrum of available practices (i.e. more or less oral/aural or silent, and intensive or extensive in practice) rather than as dichotomous entities. As such, this thesis argues for the rejection of evolutionary theories of the history of literacy, suggesting that rather than being described antithetically, historical reading practices and purposes must be recognised as complex, coexisting socio-cultural practices, and the multiplicity of reading communities within a single society must be acknowledged and analysed as such, as opposed to being interpreted as universal entities.

Guido Bonato y "El Tratado de Forlivio sobre los más principales juicios de los astros"

En esta tesis doctoral pretendo aproximarme a la figura del famoso astrólogo Guido Bonato o Bonatus, así como a su obra, el Tratado de Forlivio sobre los más principales juicios de los astros, traducción castellana llevada a cabo por Auger Ferrer en el siglo XVII (1638) del voluminoso compendio latino Registrum Guidonis Bonati de Forliuio. Decem continens tractatus Astronomie (1491). Así pues, es mi intención, en primera instancia, hacer una extensa introducción a la Historia de la Astrología desde la Antigüedad hasta el Renacimiento, contexto este último en el cual se inscribe el autor de la traducción castellana de la obra del autor latino Bonatus. Me centraré, con especial atención, en los avatares científico-teológicoastrológicos del siglo XIII, siglo en el cual el astrólogo ejerce su labor intelectual. En segundo lugar, pretendo dedicar un espacio a la vida de Guido Bonato, dando una serie de detalles y apuntes biográficos. Asimismo, he de hablar de su extensa producción astrológica en la tercera parte: el Liber astronomicus, posteriormente nombrado como Registrum Guidonis Bonati de Forliuio (1491), Decem continens tractatus astronomie (1506) y De astronomia tractatus decem (1550). En cuarto lugar, intentaré introducir al lector al significado de la extensa y compleja obra latina del astrólogo nativo de Forlí. Por último, destinaré a la quinta y última parte de este trabajo el análisis pormenorizado del Tratado de Forlivio sobre los más principales juicios de los astros. Nuestra obra se adhiere a la corriente de la llamada astrología judiciaria, concretamente a la llamada astrología de interrogaciones o astrología horaria, que predomina en las obras de los astrólogos árabes medievales, según afirma Luis Miguel Vicente García en su obra Estrellas y astrólogos en la literatura medieval española1. De hecho, la parte original latina se intitula «De interrogationibus», «Tractatus interrogationibus seu questioniis guidonis bonati» o «Tractatus super precipuis iudiciis astrorum»...

Conversación con Guido Vargas, dirigente agrario y diputado costarricense

Introducción Antonieta Camacho y Tomás Saraví, de PERSPECTIVAS RURALES, mantuvieron un extenso dialogo con Guido Vargas, de larga trayectoria en la Unión Nacional de Pequeños y Medianos Productores (UPANACIONAL) y la Mesa Nacional Campesina de Costa Rica; actualmente es diputado por el Partido Acción Laborista Agrícola (PALA).

Las relaciones comerciales de Costa Rica en el Pacífico (1575-1821)

IntroducciónLos inicios de la colonización de Costa Rica y el comercio con Panamá En 1575 podemos situar los inicios de la sociedad colonial de Costa Rica y el fin del largo periodo de inestabilidad que caracterizó a la conquista. La colonización del interior del país se sustentó en el establecimiento del régimen de encomienda sobre la población indígena de gran parte de los habitantes originales del Valle Central del país, sobrevivientes a la catástrofe demográfica provocada por la conquista española…

Molecular architecture of the human sinus node: insights into the function of the cardiac pacemaker.

BACKGROUND: Although we know much about the molecular makeup of the sinus node (SN) in small mammals, little is known about it in humans. The aims of the present study were to investigate the expression of ion channels in the human SN and to use the data to predict electrical activity. METHODS AND RESULTS: Quantitative polymerase chain reaction, in situ hybridization, and immunofluorescence were used to analyze 6 human tissue samples. Messenger RNA (mRNA) for 120 ion channels (and some related proteins) was measured in the SN, a novel paranodal area, and the right atrium (RA). The results showed, for example, that in the SN compared with the RA, there was a lower expression of Na(v)1.5, K(v)4.3, K(v)1.5, ERG, K(ir)2.1, K(ir)6.2, RyR2, SERCA2a, Cx40, and Cx43 mRNAs but a higher expression of Ca(v)1.3, Ca(v)3.1, HCN1, and HCN4 mRNAs. The expression pattern of many ion channels in the paranodal area was intermediate between that of the SN and RA; however, compared with the SN and RA, the paranodal area showed greater expression of K(v)4.2, K(ir)6.1, TASK1, SK2, and MiRP2. Expression of ion channel proteins was in agreement with expression of the corresponding mRNAs. The levels of mRNA in the SN, as a percentage of those in the RA, were used to estimate conductances of key ionic currents as a percentage of those in a mathematical model of human atrial action potential. The resulting SN model successfully produced pacemaking. CONCLUSIONS: Ion channels show a complex and heterogeneous pattern of expression in the SN, paranodal area, and RA in humans, and the expression pattern is appropriate to explain pacemaking.