Políticas de desenvolvimento urbano em espaços segregados: uma análise do PDSA na cidade de Macapá (AP)

O estudo ora apresentado evidencia o debate sobre o tema das políticas públicas voltadas para espaços segregados na cidade de Macapá (AP) sob a gestão do Programa de Desenvolimento Sustentável do Amapá (PDSA). Busca compreender a inter-relação entre as políticas públicas pautadas no discurso do desenvolvimento sustentável e o desenvolvimento urbano da cidade ao longo de dois mandatos governamentais em nível estadual pelo Partido Socialista Brasileiro (PSB) com uma proposta de desenvolvimento pautada na Agenda 21. Procura-se entender o discurso do desenvolvimento sustentável e sua aplicação como programa de governo, de modo a entender seus esforços em aplicar na cidade as diretrizes estabelecidas no âmbito estadual. Os principais resultados da investigação apresentam a dificuldade em ajustar para o espaço urbano um discurso voltado para a preservação dos recursos ambientais, bem como suas limitações às políticas urbanas em áreas segregadas, destacando-se a visão das lideranças comunitárias e do governo acerca do PDSA e de sua relação com o desenvolvimento urbano.

Políticas públicas de ecoturismo e participação: a trajetória do PROECOTUR no Pólo Belém/Costa Atlântica

O objetivo desta dissertação é analisar a implementação da política pública de ecoturismo para a região amazônica, com recorte no Programa de Desenvolvimento do Ecoturismo na Amazônia Legal (PROECOTUR), no pólo Belém/Costa Atlântica. Objetiva-se, ainda, analisar a participação dos atores sociais neste processo bem como a contribuição do Programa para o desenvolvimento sustentável na área em questão. Este estudo tem por base levantamentos bibliográficos, documentais incluindo fotografias e mapas e pesquisa de campo para a coleta de dados. Com base nestes procedimentos, descreve-se o processo de implementação deste Programa e os fatores que contribuíram para sua descontinuidade. A análise de políticas públicas de turismo, notadamente de ecoturismo, revela que estes são realidades raramente analisadas. Procura-se, então, contribuir para a ampliação dos conhecimentos sobre as mesmas. E, também, colaborar para que os atores sociais envolvidos compreendam a importância de sua participação no processo de implementação destas políticas, de tal sorte que se possa promover o desenvolvimento sustentável tão almejado.

Uma modalidade de ensino na educação: educação à distância

Pós-graduação em Serviço Social - FCHS

Análise dos processos e instrumentos de ordenação do território: comparação entre Brasil e Portugal

Pós-graduação em Geografia - IGCE

Prevalence of excessive daytime sleepiness and associated factors in women aged 35-49 years from the "Pindamonhangaba Health Project" (PROSAPIN)

OBJETIVO: Estimar a prevalência da sonolência diurna excessiva (SDE) e identificar os fatores associados em mulheres de 35 a 49 anos de idade do "Projeto de Saúde de Pindamonhangaba" (PROSAPIN). MÉTODOS: O estudo foi observacional transversal com 372 mulheres com idade entre 35 e 49 anos selecionadas aleatoriamente da Estratégia Saúde da Família (ESF) do município de Pindamonhangaba, São Paulo, onde é desenvolvido o "Projeto de Saúde de Pindamonhangaba" (PROSAPIN). A SDE foi avaliada por entrevista utilizando a Escala de Sonolência de Epworth e os fatores associados por meio de questões que investigaram as características sócio-demográficas, a história ginecológica, a presença de comorbidades, o estilo de vida, a rotina de sono e o uso de medicamentos capazes de alterar o estado de alerta, além de mensuradas as variáveis antropométricas. Estimou-se a prevalência da SDE com intervalo de confiança de 95% (IC 95%) e foram identificados os fatores associados por meio de um modelo de regressão logística múltipla realizado no Programa Stata, versão 10.0. RESULTADOS: A prevalência da SDE foi de 18,5% (IC 95%: 14,7- 22,9) e os fatores associados foram: profissão relacionada a serviços domésticos (OR = 2,2; IC 95%: 1,1-4,3), nível de atividade física acima da média da população estudada (OR = 1,9; IC 95%: 1,1-3,4); e a presença de características sugestivas de ansiedade (OR = 1,9; IC 95%: 1,1-3,4). CONCLUSÃO: A prevalência da SDE em mulheres de 35 a 49 anos do PROSAPIN foi elevada e associada à característica sociodemográfica, à presença de comorbidades e ao estilo de vida.

Metabolic engineering of beta-oxidation in Penicillium chrysogenum for improved semi-synthetic cephalosporin biosynthesis

Industrial production of semi-synthetic cephalosporins by Penicillium chrysogenum requires supplementation of the growth media with the side-chain precursor adipic acid. In glucose-limited chemostat cultures of P. chrysogenum, up to 88% of the consumed adipic acid was not recovered in cephalosporinrelated products, but used as an additional carbon and energy source for growth. This low efficiency of side-chain precursor incorporation provides an economic incentive for studying and engineering the metabolism of adipic acid in P. cluysogenum. Chemostat-based transcriptome analysis in the presence and absence of adipic acid confirmed that adipic acid metabolism in this fungus occurs via beta-oxidation. A set of 52 adipate-responsive genes included six putative genes for acyl-CoA oxidases and dehydrogenases, enzymes responsible for the first step of beta-oxidation. Subcellular localization of the differentially expressed acyl-CoA oxidases and dehydrogenases revealed that the oxidases were exclusively targeted to peroxisomes, while the dehydrogenases were found either in peroxisomes or in mitochondria. Deletion of the genes encoding the peroxisomal acyl-CoA oxidase Pc20g01800 and the mitochondrial acyl-CoA dehydrogenase Pc20g07920 resulted in a 1.6- and 3.7-fold increase in the production of the semi-synthetic cephalosporin intermediate adipoyl-6-APA, respectively. The deletion strains also showed reduced adipate consumption compared to the reference strain, indicating that engineering of the first step of beta-oxidation successfully redirected a larger fraction of adipic acid towards cephalosporin biosynthesis. (C) 2012 Elsevier Inc. All rights reserved.

THE RELATIONSHIP BETWEEN SERUM CHOLESTEROL AND CANCER INCIDENCE IN THE POPULATION OF THE HYPERTENSION DETECTION AND FOLLOW-UP PROGRAM

The relationship between serum cholesterol and cancer incidence was investigated in the population of the Hypertension Detection and Follow-up Program (HDFP). The HDFP was a multi-center trial designed to test the effectiveness of a stepped program of medication in reducing mortality associated with hypertension. Over 10,000 participants, ages 30-69, were followed with clinic and home visits for a minimum of five years. Cancer incidence was ascertained from existing study documents, which included hospitalization records, autopsy reports and death certificates. During the five years of follow-up, 286 new cancer cases were documented. The distribution of sites and total number of cases were similar to those predicted using rates from the Third National Cancer Survey. A non-fasting baseline serum cholesterol level was available for most participants. Age, sex, and race specific five-year cancer incidence rates were computed for each cholesterol quartile. Rates were also computed by smoking status, education status, and percent ideal weight quartiles. In addition, these and other factors were investigated with the use of the multiple logistic model.^ For all cancers combined, a significant inverse relationship existed between baseline serum cholesterol levels and cancer incidence. Previously documented associations between smoking, education and cancer were also demonstrated but did not account for the relationship between serum cholesterol and cancer. The relationship was more evident in males than females but this was felt to represent the different distribution of occurrence of specific cancer sites in the two sexes. The inverse relationship existed for all specific sites investigated (except breast) although a level of statistical significance was reached only for prostate carcinoma. Analyses after exclusion of cases diagnosed during the first two years of follow-up still yielded an inverse relationship. Life table analysis indicated that competing risks during the period of follow-up did not account for the existence of an inverse relationship. It is concluded that a weak inverse relationship does exist between serum cholesterol for many but not all cancer sites. This relationship is not due to confounding by other known cancer risk factors, competing risks or persons entering the study with undiagnosed cancer. Not enough information is available at the present time to determine whether this relationship is causal and further research is suggested. ^

Reauthorization of GSA and multiple award program : hearing before the Committee on Governmental Affairs, United States Senate, One Hundred Second Congress, second session, on S. 1958 ... and S. 2619 ... June 11, 1992.

"S. 1958, to authorize functions and activities under the Federal Property and Administrative Services Act of 1949, to amend laws relating to federal procurement, and for other purposes and S. 2619, to amend the Federal Property and Amdinistrative Services Act of 1949 to enact provisions governing the negotiation and award of contracts under the multiple award schedule program of the Feneral Services Administration"

An analysis of the rehabilitation system. Analytic study no. 6.

National Highway Traffic Safety Administration, Washington, D.C.

Report concerning the billing practices of public utilities providing gas service to consumers in Illinois /

Pursuant to HR 102, this report contains information pertaining to the guidelines that govern the practice of using estimates in issuing utility bills, the methodologies used by utilities in estimating usage, and standards for accuracy of metering devices.

Civilian Health and Medical Program, Department of Veterans Affairs : beneficiary information booklet.

Mode of access: Internet.

Defense Department's CHAMPUS program : hearings before the Permanent Subcommittee on Investigations of the Committee on Government Operations, United States Senate, Ninety-third Congress, second session ...

Hearing held June 9, 1976, pursuant to section 5, Senate resolution 363, 94th Congress.

Privacy in the Smart City: Implications of Sensor Network Design, Law, and Policy for Locational Privacy

Thesis (Master's)--University of Washington, 2016-06

Colorectal cancer screening in Australia: an economic evaluation of a potential biennial screening program using faecal occult blood tests

Objective: To evaluate whether the introduction of a national, co-ordinated screening program using the faecal occult blood test represents 'value-for-money' from the perspective of the Australian Government as third-party funder. Methods: The annual equivalent costs and consequences of a biennial screening program in 'steady-state' operation were estimated for the Australian population using 1996 as the reference year. Disability-adjusted life years (DALYs) and the years of life lost (YLLs) averted, and the health service costs were modelled, based on the epidemiology and the costs of colorectal cancer in Australia together with the mortality reduction achieved in randomised controlled trials. Uncertainty in the model was examined using Monte Carlo simulation methods. Results: We estimate a minimum or 'base program' of screening those aged 55 to 69 years could avert 250 deaths per annum (95% uncertainty interval 99-400), at a gross cost of $A55 million (95% UI $A46 million to $A96 million) and a gross incremental cost-effectiveness ratio of $A17,000/DALY (95% UI $A13,000/DALY to $A52,000/DALY). Extending the program to include 70 to 74-year-olds is a more effective option (cheaper and higher health gain) than including the 50 to 54-year-olds. Conclusions: The findings of this study support the case for a national program directed at the 55 to 69-year-old age group with extension to 70 to 74-year-olds if there are sufficient resources. The pilot tests recently announced in Australia provide an important opportunity to consider the age range for screening and the sources of uncertainty, identified in the modelled evaluation, to assist decisions on implementing a full national program.