Avaliação nutricional pré-cirúrgica de crianças com lesão labial e/ou palatal

Pós-graduação em Pediatria - FMB

Avaliação por meio da tomografia computadorizada de feixes cônicos e radiografia cefalométrica lateral do espaço aéreo faríngeo em indivíduos submetidos à cirurgia ortognática

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Biomarcadores renais de lesão glomerular em pacientes submetidos à anestisia para cirurgia arterial

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação dos distúrbios metabólicos de pacientes obesas, grau III, antes e depois da cirurgia bariátrica

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Análise de fatores de dor intra-operatória na cirurgia ambulatorial no câncer de mama

Pós-graduação em Psicologia do Desenvolvimento e Aprendizagem - FC

Inflamação, homeostase do ferro e suplementação nutricional na cirurgia de derivação gástrica em Y de Roux em mulheres obesas

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Efeitos de intervenção psicológica preparatória à cirurgia, no processo de adaptação pós-operatório, em pacientes submetidos à cirurgia ortognática

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Considerações anestésicas para realização da cirurgia de facoemulsificação em cães

Cataract is the leading cause of blindness in dogs. It is defined as an opacity in the lens and is independent of resulting visual deficit. Although there are a growing number of studies related to drug therapy of cataract, the treatment is still considered exclusively surgical. Among the techniques used to remove cataract, phacoemulsification is the best performer. Anesthesia in intraocular surgery has several peculiarities, which are essential to successfully conduct phacoemulsification in dogs. In these patients, a safe and effective anesthesia requires the maintenance of intraocular pressure close to normal, preventing the activation of the oculo-cardiac reflex and complete immobilization of the eye. The appropriate conditions for such surgical procedures can be established through the use of drugs from different pharmacological groups for premedication, induction and maintenance of anesthesia, making a balanced anesthesia. This work was compiled from a careful review of the literature on anesthesia in cataract surgery. Considerations on the pre-medication, induction and maintenance of anesthesia are discussed, aiming to contribute to the phacoemulsification becomes more safe and suitable for the anesthesiologist and the surgeon as well as comfortable for dogs undergoing surgery

Geração de vacinas antitumorais de células dendríticas humanas sensibilizadas com RNA de células tumorais pré-tratadas com agentes antineoplásicos

O câncer colorretal (CCR) é a terceira causa mais comum de câncer no mundo em ambos os sexos e a segunda causa em países desenvolvidos. Seu tratamento convencional é baseado na cirurgia associada à radioterapia e à quimioterapia em dose máxima tolerável, para tentativa de eliminação massiva das células tumorais. Tal abordagem, no entanto, pode causar efeitos colaterais importantes, entre eles as alterações hematopoiéticas e a supressão da resposta imune. As vacinas de células dendríticas mostram-se como opção terapêutica promissora para muitos tipos de câncer, havendo diferentes protocolos de preparação e sensibilização dessas células para dirigir a resposta antitumoral específica. Alguns agentes antineoplásicos em doses ultrabaixas mostraram modular positivamente as células dendríticas (DCs) e, na célula tumoral, promover alterações na transcrição de vários genes imunologicamente relevantes. Considerando que, em estudos prévios, tais mudanças transcricionais resultaram em aumento de imunogenicidade das células tumorais, hipotetizamos que o RNA das células pré-tratadas deve ser mais eficiente do que o RNA das células originais para preparação de vacinas de células dendríticas. Assim, objetivamos avaliar se o tratamento de células do tumor de cólon humano (HT-29) com PAC ou 5-FU/LEUCO torna seu RNA mais eficiente para preparação dessas vacinas. Para essa investigação, DCs humanas geradas a partir de monócitos de sangue periférico foram transfectadas com RNA total das células tumorais pré-tratadas e, a seguir, testadas quanto à capacidade de apresentação de antígenos e indução de células T citolíticas específicas. Apesar da baixa viabilidade celular pós eletroporação, os resultados obtidos sugerem que o tratamento de células tumorais com concentrações não tóxicas de 5-FU ou PAC promove alteração de expressão... (Resumo completo, clicar acesso eletrônico abaixo)

Mensuração e análise do ph salivar em pacientes com hiperidrose submetidos a cirurgia de simpatectomia videotoracoscópica

The study was performed to verify if there are changes in salivary pH in patients with hyperhidrosis who were treated by Videothoracoscopic Sympathectomy. Twelve patients underwent sympathectomy with clamping the sympathetic chain along the vertebrae T2, T3 and T4, under inhalation and intravenous general anesthesia and with drainage of pneumothorax through probe N° 16. These patients had their saliva collected 1 day before and 7 days after surgery for measurement of pH by the colorimetric method with indicator paper. All patients showed no sign or symptom of hyperhidrosis in the immediate postoperative period, which demonstrates the success of sympathetic denervation on these levels. No patient had compensatory sweating and there was no post-operatively surgical complication. No drug or substance has been administered to patients for the study. The pH results obtained were analyzed using test ´´t´´ Student. Although the average pH in samples obtained after surgery was lower than the preoperative, the test revealed no statistically significant difference (p = 0.181). It is concluded that sympathectomy, an excellent therapeutic and definitive method for hyperhidrosis, does not alter the salivary pH, and so, did not influence the cariogenic process

Estabilidade sagital da condiloplastia associada à cirurgia ortognática para o tratamento do osteocondroma mandibular

The aim of this study was to evaluate the stability of the conservative condylectomy technique and articular disc repositioning as the surgical treatment approach for management of mandibular condylar osteochondroma, with appropriate Orthognathic surgery. Fifteen patients (12 females and 3 males), average age of 32.3 years (range, 13 to 56 years), with unilateral active osteochondroma of the mandibular condyle were analyzed. All patients underwent conservative condylectomy, recontouring of the remaining condylar neck stump and articular disc repositioned and indicated orthognatic surgical procedures. Average post surgical follow-up was 19 months. Each patient's lateral cephalograms were traced at 3 intervals (presurgery, immediate post surgery and long-term follow-up). Immediate after surgery the oclusal plane angle decreased -2.8 ± 4.5o, the maxillomandibular complex rotated counter-clockwise with advancement at menton 5.3 ± 5.6 mm, pogonion 5.0 ± 5.1 mm, B point 3.4 ± 4.2 mm and A point 1.0 ± 1.5 mm. The long-term follow-up showed significant changes in overbite (-0.6 ± 0.5 mm) and SNGoMe (0,93° ± 1,53°). Horizontally and vertically small instabilities occurred in Me (-1.21 ± 1.94 mm) and PNS (-1.48 ± 1.67 mm) respectively. The treatment protocol studied produced counterclockwise rotation and maxillofacial mandibular advancement. The long-term follow-up showed solid dental and skeletal stability with horizontal instability of Me and PNS in the vertical direction.

Prevalência de alterações sistêmicas em pacientes atendidos na disciplina de cirurgia e traumatologia bucomaxilofacial do curso de Odontologia da UNIARA

Introduction: pre-operative assessment is of fundamental importance for the prevention of transoperative and of postoperative complications. Objective: to identify the prevalence of diseases and systemic conditions in patients undergoing surgical treatment in the discipline of surgery and Traumatology of University Center of Araraquara, in the period of 2004 to 2009. Material and method: for the development of this study, a survey in medical records of patients was performed and the factors considered included: age, sex, presence of vices, and systemic conditions that affect the world’s population. The data obtained were analyzed quantitatively and recorded in a table. Result:  Considering all patient records analyzed (693), 340 affirmative responses were detected (49,06%) to one or more diseases. Cardiovascular diseases were the most prevalent (22,34%). Considering the prevalence of diseases related to age, the age of less than 20 years represented 16,32%; of 20-29 years, 43,06%; 30-39 years, 45,16%; 40-44 years, 48,64%; 45-49 years, 56,25%; 50-54 years, 58,33%; 55-59 years, 57,74%; 60-64 years, 70,37%; 65-69 years, 66,66%; and 70 years or more, 68,75%. Conclusion: diseases and systemic alterations with higher prevalence were cardiovascular diseases, anemia, sinusitis and diabetes. The frequency of affirmative answers to systemic conditions was age-dependent and there was a predominance of females. The tobacco addiction was the most frequent. Thus, it was found that the preoperative assessment of the health of patients who will undergo surgical dental treatment is of fundamental importance.

Estudo microbiológico comparativo entre sabão de clorexidina 2% e um novo sabão antisséptico para lavagem pré-operatória das mãos

Objective: To evaluate, by means of a microbiologic study, two kinds of soaps suggested by surgeons for presurgical handwashing, comparing a well-known antibacterial soap with a new soap formulated from vegetable oils. Materials and methods: Ten volunteers performed handwashing according to previously established protocols for routine antisepsis in operating rooms using 3 different soaps: a common, commercially marketed soap, serving as the control group (Group 1), with no antibacterial characteristics; a soap with 2% chlorhexidine (Group II); and a new soap formulated from vegetable oils at a concentration of 20%, known as surfactant, which was designed by the Chemistry Institute (Unesp/Araraquara – Grupo de Materiais Fotônicos) (Group III). The microbiological samples were collected immediately before and after handwashing and one hour later with the volunteer wearing surgical gloves. Results: ANOVA revealed that the following significant differences are found in the number of bacterial colonies: between soap types (a smaller number of colonies in the Group II soap), between periods (reduction in the number of colonies in the Group II soap), and the significant effect of the soap versus time interaction. Conclusion: The 2% chlorhexidine soap performed better in reducing the number of bacterial colonies on the hands immediately after handwashing and after one hour with the use of surgical gloves, when compared to the 20% surfactant soap.

Uma experiência terapêutica pré-cirurgica:o uso do desenho como mediador lúdico

Hospitalization is usually steeped in fantasies that generate high levels of anxiety, especially for children. Therefore, the hospital psychotherapeutic process must propose actions to enable them to develop internal resources to cope with situation that causes anxiety. This article aims to demonstrate the importance of psychological intervention through drawings as mediators in the pre-surgical context of orthopedic correction in the hospital. This patient made seven drawings that at first expressed her anguish towards the surgery and at the end showed her attempt to elaborate. We conclude that drawing is an important therapeutic tool in the hospital.

Avaliação algimétrica por estímulo nociceptivo térmico e pressórico em cães pré-tratados com levomepromazina, midazolam e quetamina associados ou não ao butorfanol ou buprenorfina

This study aimed at quantifies the pain in dogs under dissociative anesthesia, across thermal and pressoric stimulus and quantify the reasonable period between two different opioids analgesics. In this study, 30 dogs were used and, divided into three groups of 10 animals each, in which the animals of GI received methotrimeprazine and midazolam put on the same syringe with ketamine. The animals of GII received the same treatment of GI but associated with butorphanol and finally the animals of GIII received the same treatment of GI but associated with buprenorphine. The routine parametric evaluations has been proceeded, although using the thermo algimetry measured in degrees C with the average of 52 degrees C and the pressoric algimetry in Kg. In the thermo algimetry, there has been significant difference in GI at the moments M0, M1, M4 and M5; in GII it was found at M0, M1, M5 and M6 and in GIII it was observed the significant at M0 and M1. It has also been shown in pressoric algimetry significant difference in GI at the moments M0, M2 and M3. Among GII it has observed significant difference at all moments and it has found at M0, M9 in GIII. Thus, it has observed significant differences between all groups; for such the M2 of GII smaller than the others; and M4, M5 of GIII bigger than GI and GII. In the assessment of all periods it was observed significant latent period bigger in GI, however, with reasonable period and short recovery in GII and GIII. In the order hand, the postural tonus recovery it was longer in GIII, followed by GII and finally GI. The used method for the measurement of algic stimulus was efficient, noticing a reasonable analgesic period of 3 hours for butorphanol and 6 hours for buprenorphine.