Maturidade pulmonar fetal em gestações complicadas por diabete ou hiperglicemia leve

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Avaliação da atividade hipoglicemiante do extrato bruto de Bauhinia holophylla (Steud.) em camundongos diabéticos induzidos por estreptozotocina

Pós-graduação em Biologia Geral e Aplicada - IBB

Avaliação da atividade hipoglicemiante do extrato de Myrcia bella em camundongos diabéticos por estreptozotocina

Pós-graduação em Biologia Geral e Aplicada - IBB

Inflamação, homeostase do ferro e suplementação nutricional na cirurgia de derivação gástrica em Y de Roux em mulheres obesas

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Does hyperglycemia in pregnancy change fetal kidney growth?: a longitudinal prospective study

PURPOSE: To measure fetal renal volume in normoglycemic and hyperglycemic pregnancies. METHODS: A longitudinal prospective study was conducted and included 92 hyperglycemic and 339 normoglycemic pregnant women attended at the prenatal service of a hospital from Rio de Janeiro State. Ultrasound examinations were performed to estimate gestational age at baseline and the kidney volume was estimated using the prolate ellipsoid volume equation. RESULTS: Fetal kidney volume growth between normoglycemic and hyperglycemic pregnancies are significantly different. The fetal kidney volume growth in pregnancy is positively correlated with gestational age explained by these predictor equations, by group: normal renal volume = exp (6.186+0.09×gestational week); hyperglycemic renal volume = exp (6.978+0.071×gestational week) and an excessive growth pattern for hyperglycemic pregnancies may be established according to gestational age. CONCLUSION: This is important for early detection of abnormalities in pregnancy, particularly in diabetic mothers.

Efeitos do diabetes gestacional moderado e da reposição com insulina na lactação sobre a próstata ventral do rato Wistar

Pós-graduação em Biologia Geral e Aplicada - IBB

Estudo de fase clínica I utilizando membrana de quitosana dopada com hormônios derivados de plaquetas

Pós-graduação em Pesquisa e Desenvolvimento (Biotecnologia Médica) - FMB

Imunologia das interações materno-fetais no diabete e na hiperglicemia gestacional leve

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Heart rate variability in children with type 1 diabetes mellitus

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Gait stability in diabetic peripheral neuropathy

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Alterações da matriz extracelular causadas pelo diabetes: o impacto sobre a continência urinária

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Efeito do diabete induzido por streptozotocin na matriz extracelular e no músculo estriado uretral em ratas prenhes

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Spirulina e exercício físico no controle do metabolismo muscular da glicose em ratos diabéticos

O Diabetes mellitus é um problema de saúde pública mundial. Tal doença é caracterizada pela redução da secreção (Diabetes mellitus tipo1) ou da ação (Diabetes mellitus tipo2) da insulina, acarretando hiperglicemia, além de alterações no metabolismo das proteínas e dos lipídeos. As consequências para o organismo são variadas, incluindo hipertensão, nefropatias, retinopatias e cardiopatias. Atualmente existe grande interesse nas ervas medicinais, como hipoglicemiantes naturais, entre elas, a spirulina. A spirulina parece ser boa fonte protéica para a alimentação, tem boa aceitação e não apresenta efeitos tóxicos aparentes. Além disso, ela pode exercer efeitos benéficos no tratamento de algumas doenças como câncer, desnutrição, obesidade, hipercolesterolemia, hipertensão arterial, diabetes mellitus,entre outras. Tendo em vista a grande possibilidade utilizar a spirulina na dieta, o presente estudo visa analisar o metabolismo muscular da glicose em ratos diabéticos. Não foram encontradas diferenças significativas entre os grupos nas variáveis metabólicas estudadas

Manifestações oculares na leishmaniose

The Canine Visceral Leishmaniasis is a chronic disease of endemic character, caused by Leishmania Chagasi in Americas. The inoculation of the promastigote form in the individual triggers a local and widespread immune reaction with formation of inflammatory infiltrates and deposition of immune complexes in tissues. Initial clinical symptoms of the disease are: weight reduction, hepatomegaly, splenomegaly and, according to the disease chronicity, signs such as alopecia, erythema, onychogryphosis, arthropathies, renal diseases, pyoderma, seborrheic dermatitis, muscle atrophy and Ocular diseases. Ocular diseases are often reported and are result of the direct parasitism or immune-mediated mechanisms caused by the disease. The Leishmania spp have greater affinity for the anterior segment, so that anterior uveitis is one of the most frequently diagnosed injuries. Blepharitis diffuse and Keratoconjunctivitis also appear as important ocular changes. In histological section, inflammatory infiltrates and macrophages with amastigote form are observed in all ocular tissues, with the exception of the retina and optical nerve. In the clinical analysis and disease diagnosis, should be considered the differential diagnosis, such as Ehrlichiosis and systemic hypertension, because these may cause some ocular manifestations similar to those observed in leishmaniasis

Implementation of physiotherapeutic shares in the prevention of diabetes complications in a Family Health Strategy

Introduction In the Family Health Strategy (FHS), the treatment of Diabetes Mellitus (DM) includes education and lifestyle change strategies. Physiotherapists have a key role in this health setting. Objectives To implement actions of evaluation and guidelines for patients with type 2 DM who attend a Family Health Strategy (FHS), regarding diabetic foot and the practice of regular physical exercise in the control and prevention of the complications of Diabetes Mellitus. Methods 17 individuals from an FHS were evaluated, with the following procedures: clinical and anthropometric parameters, inspection, a questionnaire on diabetic neuropathy, tests of vibratory and tactile sensitivity, muscle function, range of motion, functional analysis, questions about exercise practice and guidance regarding controlling blood glucose and foot care. Results Deformities, dry skin, calluses, dehydration, ulceration, cracking and brittle nails were found. Peripheral neuropathy was not observed; tactile sensitivity was altered in the heel region and the vibratory sense was absent in 5% of individuals. A decrease in functionality of ankle movements was verified. Of the participants, 76% were sedentary, 24% knew about the benefits of practicing regular exercise, 25% had undergone a medical evaluation prior to performing physical exercise and, of these, 25% were supervised by a qualified professional. Discussion The implementation of physiotherapy actions in diabetics from an FHS was important for highlighting the presence of risk factors for diabetic complications. Conclusions Individuals attending the FHS need more information and programs for the prevention of diabetic complications.