940 resultados para Doença Mental Grave


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Pós-graduação em Saúde Coletiva - FMB

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Currently , as a result of the significant increase in the number of elderly, one can observe an increase in the number of chronic diseases , among them Alzheimer's disease (AD) , which affects both patients and their caregivers , that due care with the patient , just overwhelmed , anxious and depressed. Therefore, this study aims to draw a profile of caregivers of Alzheimer's patients, correlating the physical activity of patients with levels of overload, anxiety, depression caregivers. For both sample consisted of 40 patients with AD to characterize the physical activity levels and perform activities of daily living. In addition, we evaluated 40 caregivers. Patient assessment was made through a medical history, beyond the score Clinical Dementia Rating (CDR), Mini - Mental State Examination (MMSE), Modified Baecke Questionnaire for Older Adults (MBQ) , Functional Activities Questionnaire PFEFFER (QAFP) , and the Self Perception Performance in Activities of Daily Living (EAPAVD). For assessing the caregiver was also used an interview, then the Neuropsychiatric Inventory (NPI), anxiety and depression scale (HAD) Scale and the Zarit caregiver burden (Zarit). The data were processed using descriptive procedures for the analysis of characterization of samples, such as cognitive screening and physical activity level and profile of caregivers. There was a normal distribution of the data using the Shapiro Wilk, For data with normal distribution were used parametric descriptive procedures using One Way ANOVA to compare groups and applying a post hoc Bonferroni. As for the data that showed the destruction not normal was used to standardize the test by Z -score , and then treated by means of parametric statistical procedures , as presented earlier . The Pearson correlation was used to identify possible associations between variables. It was assumed significance level of 5 % (p ≤ 0.05) for all analyzes. Given these results, we conclude that...

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A doença de Parkinson (DP) é uma doença neurodegenerativa que afeta principalmente o controle motor com reflexos negativos no desempenho funcional de seus pacientes. Alterações no equilíbrio podem levar à diminuição da independência e funcionalidade. Alguns estudos evidenciam os benefícios do exercício físico, como alternativa nãofarmacológica para esses pacientes. Objetivo: O presente trabalho analisou e comparou os efeitos de dois programas de atividade física sobre o risco de quedas e o equilíbrio funcional em pacientes com doença de Parkinson. O presente estudo também teve como objetivo verificar a associação entre as variáveis clínicas e comportamentais. Método: Participaram do estudo 30 pacientes com DP idiopática entre os estágios I a III na escala de estagiamento clínico de Hoehn & Yahr, sendo distribuídos em três grupos: grupo de treinamento com pesos (GTP), atividade física generalizada (GAFG) e o grupo controle (GC). O período de intervenção para o GTP e o GAFG foi de quatro meses. As avaliações foram realizadas com os participantes na fase “on” da medicação. Para avaliar o equilíbrio dinâmico juntamente com o risco de quedas foi utilizado o teste Timed Up and Go (TUG) e, para analisar o risco de quedas foi utilizada a Escala de Equilíbrio Funcional de Berg (EEFB). As avaliações clínicas foram realizadas por meio da Unified Parkinson’s Disease Rating Scale (sub-escalas funcional e motora), escala de nível de gravidade da doença de Hohen & Yahr e Mini-Exame do Estado Mental (MEEM). O teste U de Mann-Whitney foi utilizado para comparação das variáveis analisadas entre os três grupos separadamente por momento do treinamento. Resultados: Apenas em relação à EEFB foram encontradas diferenças significativas entre os grupos, com pior desempenho para o grupo controle (GC). Conclusão: Foi possível observar que: os pacientes... (Resumo completo, clicar acesso eletrônico abaixo)

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The Alzheimer's disease (AD) is a neurodegenerative and progressive disease, mostly seen in elderly people, characterized by memory loss. This commitment leads causes deficits in functional capacity, compromising the individual in execution of activities of daily living, like dressing and bathing. This study, with a longitudinal character, aimed analyze the effects of a protocol of weights training (WT) in global cognitive status and realization of activities of daily living (ADL´s) basic and instrumental in AD patients, comparing the effects of four months of WT in the performance of ADL´s in global cognitive status. And also aimed to verify the possible relations between ADL's and global cognitive status of patients before and after the experimental period. The study included 24 patients with clinical diagnosis of AD, divided into two groups: a) training group (TG) consisted of 13 patients who underwent a protocol of WT b) Social Gathering Group (SCG) consists of 11 patients participating in a protocol of social gathering not systematized with activities of reading, writing and walking. Both protocols lasted four months, being developed in three non-consecutive weekly sessions, lasting 60 minutes each. To quantify global cognitive status and the basic and instrumental ADLs were used, respectively, the Mini-Mental State Examination and the Self Perception of Performance in Activities of Daily Living, along with the battery of tests of Activities of Daily Life of Andreotti and Okuma (1999). To analyze the results where complied the nature of the data, using analysis of variance for repeated measures ANOVA two-way and Pearson correlation for continuous data and tests of U Mann Whitney, Wilcoxon and Spearman correlation for non-continuous data, assuming level significance of 5% for all analysis. After analysis it´s possible... (Complete abstract click electronic access below)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Currently it is clear that there are several factors that can act as modifiers of diseases, without causing them directly, but having the potential to make these conditions to progress faster and more severe. There is a growing number of studies investigating the relationship between Diabetes Mellitus (DM) and Periodontal Disease (PD), including some studies focusing on the influence of genetic factors in this process. The aim of this study was to verify through a literature review, the influence of genetic polymorphisms in the development of PD in patients with DM. PubMed and BIREME were used as databases and the terms Periodontitis or Periodontal Disease, Polymorphism, Diabetes Mellitus were searched. After a refinement in the literature, five studies were selected and they were related to chronic PD with DM and polymorphisms in cytokine genes, especially interleukin 1 (IL1) e IL6. Polymorphisms were associated with a higher concentration of pro-inflammatory cytokines in the gingival crevicular fluid of diabetic patients when compared to non-diabetic. In conclusion, it is necessary to confirm this association with longitudinal studies that must investigate a larger number of cytokine genes in order to understand the cause-effect relationship between genetic polymorphisms, DM and PD.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Pós-graduação em Serviço Social - FCHS

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)