How two become one: HJURP dimerization drives CENP-A assembly

CENP‐A containing nucleosomes epigenetically specify centromere position on chromosomes. Deposition of CENP‐A into chromatin is mediated by HJURP, a specific CENP‐A chaperone. Paradoxically, HJURP binding sterically prevents dimerization of CENP‐A, which is critical to form functional centromeric nucleosomes. A recent publication in The EMBO Journal (Zasadzińska et al, 2013) demonstrates that HJURP itself dimerizes through a C‐terminal repeat region, which is essential for centromeric assembly of nascent CENP‐A.

Morphomechanical Innovation Drives Explosive Seed Dispersal

How mechanical and biological processes are coordinated across cells, tissues, and organs to produce complex traits is a key question in biology. Cardamine hirsuta, a relative of Arabidopsis thaliana, uses an explosive mechanism to disperse its seeds. We show that this trait evolved through morphomechanical innovations at different spatial scales. At the organ scale, tension within the fruit wall generates the elastic energy required for explosion. This tension is produced by differential contraction of fruit wall tissues through an active mechanism involving turgor pressure, cell geometry, and wall properties of the epidermis. Explosive release of this tension is controlled at the cellular scale by asymmetric lignin deposition within endocarp b cells-a striking pattern that is strictly associated with explosive pod shatter across the Brassicaceae plant family. By bridging these different scales, we present an integrated mechanism for explosive seed dispersal that links evolutionary novelty with complex trait innovation.

Study on hydrostatic drives for small AGT vehicles /

Mode of access: Internet.

How to see Edinburgh, the Trossachs, and the Burns and Scott country, conducted drives and day tours.

Mode of access: Internet.

Household hazardous materials and waste : public education, participation in collection drives, and amounts in homes /

"HWRIC RR-026."

Tests of the transmitting capacities of different pulleys in leather belt drives.

"A paper read before the National Association of Cotton Manufacturers at its Ninety-first Meeting, Manchester, Vermont, September 29, 1911."

Drives and walks; Chicago

W.A. Otis and E.H. Clark, architects. O.C. Simonds & Co., landscape gardeners. Unsigned. 70 cm. x 74 cm. Scale: 1"=100' [from photographic copy by Lance Burgharrdt]

Estate of Mr. W.V. Kelley. Plan of proposed improvement, showing building sites, drives, pond and property divisions

Red, black ink on linen; signed; 112 x 72 cm; Scale: 1" = 100' [from photographic copy by Lance Burgharrdt]

Plan of drives, drains and electric light conduit, grounds of Mr. H. B. Clow

Pencil, ink on linen; signed; 114 x 42 cm. Scale: 1"=50' [from photographic copy by Lance Burgharrdt]

Leçons sur l'intégration des équations aux dérivées partielles du premier ordre; faites à la Faculté des sciences de Paris aux candidats à l'agrégation.

Mode of access: Internet.

Leçons sur l'intégration des équations aux dérivées partielles du premier ordre; faites à la Faculté des sciences de Paris aux candidats à l'agrégation.

Mode of access: Internet.

Going global with assessment: what to do when the dominant culture's literacy drives assessment

This article explores how the dominant cultural literacy in a western context relies on a western template of knowledge that can inhibit internationalisation of the curricula unless it is identified, transformed, and broadened to become interculturally responsive. As Brian Street has said "literacies may be sites of negotiation and transform ation" (1994, p. 99). Drawing on the findings of an innovative website, Worldmarks , developed at Queensland University of Technology, as well as qualitative interviews with international students and staff, this article addresses the serious implications of assessment driven by the dominant culture's literacy. We identify how and why assessment driven by responsive cultural literacy enables all students to develop comprehensive intercultural communication skills and understandings as part of their lifelong learning in Australian universities.

Reinforcement drives rapid allopatric speciation

Allopatric speciation results from geographic isolation between populations. In the absence of gene flow, reproductive isolation arises gradually and incidentally as a result of mutation, genetic drift and the indirect effects of natural selection driving local adaptation(1-3). In contrast, speciation by reinforcement is driven directly by natural selection against maladaptive hybridization(1,4). This gives individuals that choose the traits of their own lineage greater fitness, potentially leading to rapid speciation between the lineages(1,4). Reinforcing natural selection on a population of one of the lineages in a mosaic contact zone could also result in divergence of the population from the allopatric range of its own lineage outside the zone(4-6). Here we test this with molecular data, experimental crosses, field measurements and mate choice experiments in a mosaic contact zone between two lineages of a rainforest frog. We show that reinforcing natural selection has resulted in significant premating isolation of a population in the contact zone not only from the other lineage but also, incidentally, from the closely related main range of its own lineage. Thus we show the potential for reinforcement to drive rapid allopatric speciation.