Catalogue of a very select collection of books, English and foreign, offered at the low prices affixed by Henry G. Bohn.

Mode of access: Internet.

"A peep into the past": Brighton in the olden time, with glances at the present.

Mode of access: Internet.

[Works,

v.1. Riding recollections.--v.2. Katerfelto.--v.3. Uncle John.--v.4. Market Harborough. Inside the bar.--v.5. Contraband.--v.6. M. or N.--v.7. Tilbury Nogo.--v.8. Songs and verses. Bones and I.--v.9. Black but comely.--v.10. The Brookes of Bridlemere.--v.11. The white rose.--v.12. Roy's wife.--v.13. Satanella.--v.14. Digby Grand.--v.15. Sarchedon.--v.16. Sister Louis. Rosine.--v.17. Kate Coventry.--v.18. Cerise.--v.19. The queen's Maries.--v.20. Holmby house.--v.21. General Bounce.--v.22. The gladiators.--v.23. Good for nothing.--v.24. The interpreter.

Brief memoir of Major-Gen. Sir John Geo. Woodford; a paper read to the Keswick Literary and Scientific Society, March 20th, 1880.

Mode of access: Internet.

Anaximenea /

Vita.

Readings in the law of real property; an elementary collection of authorities for students,

Mode of access: Internet.

Select cases and other authorities on the law of mortgage,

Mode of access: Internet.

Noctes Ambrosianae,

"Christopher in the tent". and a poem "Metrieum symposium ambrosianum.

Poems by George Forester [pseud.]

Mode of access: Internet.

Athenae cantabrigienses.

Vol. 3 published by Bowes & Bowes, 1913.

The morning message; a selection for daily meditation, from the works of Rev. G. Campbell Morgan, D. D.

Mode of access: Internet.

Lynch syndrome-associated breast cancers: clinicopathologic characteristics of a case series from the colon cancer family registry

Purpose: The recognition of breast cancer as a spectrum tumor in Lynch syndrome remains controversial. The aim of this study was to explore features of breast cancers arising in Lynch syndrome families. Experimental Design: This observational study involved 107 cases of breast cancer identified from the Colorectal Cancer Family Registry (Colon CFR) from 90 families in which (a) both breast and colon cancer co-occurred, (b) families met either modified Amsterdam criteria, or had at least one early-onset (<50 years) colorectal cancer, and (c) breast tissue was available within the biospecimen repository for mismatch repair (MMR) testing. Eligibility criteria for enrollment in the Colon CFR are available online. Breast cancers were reviewed by one pathologist. Tumor sections were stained for MLH1, PMS2, MSH2, and MSH6, and underwent microsatellite instability testing. Results: Breast cancer arose in 35 mutation carriers, and of these, 18 (51%) showed immunohistochemical absence of MMR protein corresponding to the MMR gene mutation segregating the family. MMR-deficient breast cancers were more likely to be poorly differentiated (P = 0.005) with a high mitotic index (P = 0.002), steroid hormone receptor–negative (estrogen receptor, P = 0.031; progesterone receptor, P = 0.022), and to have peritumoral lymphocytes (P = 0.015), confluent necrosis (P = 0.002), and growth in solid sheets (P < 0.001) similar to their colorectal counterparts. No difference in age of onset was noted between the MMR-deficient and MMR-intact groups. Conclusions: MMR deficiency was identified in 51% of breast cancers arising in known mutation carriers. Breast cancer therefore may represent a valid tissue option for the detection of MMR deficiency in which spectrum tumors are lacking