Maternal separation followed by isolation-housing differentially affects prepulse inhibition of the acoustic startle response in C57BL/6 mice

Exposure to chronic stress is associated with an increased incidence of neuropsychiatric dysfunction. The current study evaluated two competing hypotheses, the cumulative stress and the match/mismatch hypothesis of neuropsychiatric dysfunction, using two paradigms relating to exposure to “stress”: pre-weaning maternal separation and post-weaning isolation-housing. C57BL/6 offspring were reared under four conditions: typical animal facility rearing (AFR, control), early handling (EH, daily 15 min separation from dam), maternal separation (MS, daily 4 hr separation from dam), and maternal and peer separation (MPS, daily 4 hr separation from dam and from littermates). After weaning, mice were either housed socially (2–3/cage) or in isolation (1/cage) and then tested for prepulse inhibition in adulthood. Isolation-housed MPS subjects displayed greater deficits in prepulse inhibition relative to socially-housed MPS subjects while socially-housed AFR subjects displayed greater deficits in prepulse inhibition relative to isolation-housed AFR subjects. The results indicate that these treatment conditions represent a potentially valuable model for evaluating the match/mismatch hypothesis in regards to neuropsychiatric dysfunction.

A post project evaluation of the Columbus Alcohol Safety Action Program. Section IV - volume 2. Final report.

National Highway Traffic Safety Administration, Office of Driver and Pedestrian Programs, Washington, D.C.

An analysis of the post advertising telephone survey: 1975. Final report.

National Highway Traffic Safety Administration, Office of Alcohol Countermeasures, Washington, D.C.

Comparative estimates of post-consumer solid waste /

Includes bibliographical references (p. 18).

Collection of post-ASAP data and preparation of analytic studies for the Oregon ASAP. Final report.

National Highway Traffic Safety Administration, Washington, D.C.

Final post-ASAP progress report - Puerto Rico Alcohol Safety Action Project.

National Highway Traffic Safety Commission, Washington, D.C.

Post ASAP analysis of project impact on ultimate measures of performance, level III - analytic study one. 1975-1976 period. Final report.

National Highway Traffic Safety Administration, Office of Driver and Pedestrian Programs, Washington, D.C.

Civil service reform oversight--1980 : equal employment opportunity : hearing before the Subcommittee on the Civil Service of the Committee on Post Office and Civil Service, House of Representatives, Ninety-sixth Congress, second session, June 10, 1980.

Item 1022.

Minerals Separation, Ltd., et al., plaintiffs-petitioners, vs. Butte & Superior Mining Company, defendant-respondent. Brief for defendant-respondent. Thomas F. Sheridan [and others]

Cover-title.

Programs and schools.

"A supplement to the directory of postsecondary schools with occupational programs."

Illinois model pilot early childhood parental training programs : FY 90 summary report.

"April, 1991."

On the use of impact theory for slender configurations exhibiting flow separation /

Photocopy.

Evaluation of a Post Discharge Intervention on 30-Day Re-admission and Emergency Room Use in Patients with Diabetes A Pilot Program

Thesis (Master's)--University of Washington, 2016-06

A preliminary investigation of parenting attributes of Australian foster carers

Utilising a comparison research design of mothers involved in fostering (N= 28) and their peers (N =28), the major findings were that within the fostering group, those who had been fostering the longest had the lowest sense of efficacy, reflecting that the experience of providing foster care eroded parents' sense of their own skill. In terms of attachment to the children, the data suggested that foster carers may resist becoming too close to the children in their care in order to limit the emotional cost of subsequent separation. Importantly, there was no significant correlation between the length of time in providing foster care and marital satisfaction, which supports the notion that providing foster care does not, in itself cause marital stress. While formal support services were more utilised by foster carers there was some indication that this group is not well integrated into the broader community. Collectively, these findings demonstrate that over the long- term providing fostering care has some negative consequences for the carers in terms of their self-confidence. Agencies designated to work with carers need to consider proactive strategies to reduce this consequence.