Planets and people.

Suspended with July 1909.

Interim report to the majority leader, Illinois House of Representatives : DCFS Pilot Program : permanency and stability for children in the care of elderly/frail adoptive parents and subsidized guardians /

"December 2006"

The life of Lady Guion / written in French, by herself, now abridged, and translated into English. Exhibiting her eminent piety, charity, meekness, resignation, fortitude and stability; her labours, travels, sufferings and services, for the conversion of souls to God; and her great success, in some places, in that best of all employments on the earth. To which are added, accounts of the lives of worthy persons, whose memories were dear to Lady Guion.

"From an English edition, published at Bristol: with a few abridgements, etc."

Concerning the earths in our solar system, which are called planets, and concerning the earths in the starry heaven. Together with an account of their inhabitants, and also of the spirits and angels there : from what has been seen and heard /

Cf. J. Hyde. A bibliography of the works of Emanuel Swedenborg (no. 959).

The new American grammar of the elements of astronomy, on an improved plan: in three books. I. The use of the terrestrial globe in the solution of geographical and astronomical problems. II. The use of the celestial globe in the solution of problems, relative to the sun, planets, and fixed stars. III. The solar system, and the firmament of fixed stars. The whole systematically arranged and scientifically illustrated; with several cuts and engravings; and adapted to the instruction of youth in schools and academies.

Mode of access: Internet.

Astronomy, as it is known at the present day : to which is added,a supplement, containing an account of the nature and use of astronomical instruments, the manner of calculating the notes of the calendar, the distances and magnitudes of the planets, and a number of other useful and interesting calculations in astronomy /

Mode of access: Internet.

Observational patrol of the moon and planets and analysis of the nature of their markings; : final report.

"New Mexico State University Research Center ... AF 19(604)-5570. May 1961. Prepared for Geophysics Research Directorate, Air Force Cambridge Research Center, Air Research and Development Command, United States Air Force, Bedford, Massachusetts."

Policy for commercial agriculture : its relation to economic growth and stability /

"November 22, 1957."

A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability

Cyclotides are a fascinating family of plant-derived peptides characterized by their head-to-tail cyclized backbone and knotted arrangement of three disulfide bonds. This conserved structural architecture, termed the CCK (cyclic cystine knot), is responsible for their exceptional resistance to thermal, chemical and enzymatic degradation. Cyclotides have a variety of biological activities, but their insecticidal activities suggest that their primary function is in plant defence. In the present study, we determined the cyclotide content of the sweet violet Viola odorata, a member of the Violaceae family. We identified 30 cyclotides from the aerial parts and roots of this plant, 13 of which are novel sequences. The new sequences provide information about the natural diversity of cyclotides and the role of particular residues in defining structure and function. As many of the biological activities of cyclotides appear to be associated with membrane interactions, we used haemolytic activity as a marker of bioactivity for a selection of the new cyclotides. The new cyclotides were tested for their ability to resist proteolysis by a range of enzymes and, in common with other cyclotides, were completely resistant to trypsin, pepsin and thermolysin. The results show that while biological activity varies with the sequence, the proteolytic stability of the framework does not, and appears to be an inherent feature of the cyclotide framework. The structure of one of the new cyclotides, cycloviolacin O14, was determined and shown to contain the CCK motif. This study confirms that cyclotides may be regarded as a natural combinatorial template that displays a variety of peptide epitopes most likely targeted to a range of plant pests and pathogens.

Measurement and stability of FTY720 in human whole blood by high-performance liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry

We report here a validated method for the quantification of a new immunosuppressant drug FTY720, using HPLC-tandem mass spectrometry. Whole blood samples (500 mu l) were subjected to liquid-liquid extraction, in the presence of an internal standard (Y-32919). Mass spectrometric detection was by selected reaction monitoring with an atmospheric pressure chemical ionization source in positive ionization mode (FTY720: m/z 308.3 -> 255.3). The assay was linear from 0.2 to 25 mu g/l (r(2) > 0.997, n = 5). The inter- and intra-day analytical recovery and imprecision for quality control samples (0.5, 7 and 15 mu g/l) were 95.8-103.2 and < 5.5%, respectively. At the lower limit of quantification (0.2 mu g/l) the interand intra-day analytical recovery was 99.0-102.8% with imprecision of < 7.6% (n = 5). The assay had a mean relative recovery of 100.5 +/- 5.8% (n = 15). Extracted samples were stable for 16 h. IFTY720 quality control samples were stable at room temperature for 16 h at 4 degrees C for at least 8 days and when taken through at least three freeze-thaw cycles. In conclusion, the method described displays analytical performance characteristics that are suitable for pharmacokinetic studies in humans. (c) 2006 Elsevier B.V. All rights reserved.

Heritability and Stability of Resting Blood Pressure in Australian Twins

In Australian twins participating in three different studies (1979-1996), the contribution of genetic and environmental influences to variation in resting systolic (SBP) and diastolic blood pressure (DBP) was studied. The sample consisted of 368 monozygotic and 335 dizygotic twin pairs with measurements for both individuals. Blood pressure measurements in two studies were available for 115 complete twin pairs, and 49 twin pairs had measurements in three studies. This allowed assessment of blood pressure tracking over an average period of 12 years in the age range of 23 to 45 years. Multivariate analyses showed significant heritability (h(2)) of blood pressure in all studies (SBP h(2) = 19%-56%, DBP h(2) = 37%-52%). In addition, the analyses showed that the blood pressure tracking was explained by the same set of genetic factors. These results replicate an earlier finding in Dutch twins that also showed stability of the contribution of genetic factors to blood pressure tracking.